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The machine learning technique of persistent homology classifies complex systems or datasets by computing their topological features over a range of characteristic scales. There is growing interest in applying persistent homology to…

Optics · Physics 2021-03-03 Daniel Leykam , Dimitris G Angelakis

Dermatologists often diagnose or rule out early melanoma by evaluating the follow-up dermoscopic images of skin lesions. However, existing algorithms for early melanoma diagnosis are developed using single time-point images of lesions.…

Image and Video Processing · Electrical Eng. & Systems 2021-10-13 Zhen Yu , Jennifer Nguyen , Toan D Nguyen , John Kelly , Catriona Mclean , Paul Bonnington , Lei Zhang , Victoria Mar , Zongyuan Ge

In medical image analysis, feature engineering plays an important role in the design and performance of machine learning models. Persistent homology (PH), from the field of topological data analysis (TDA), demonstrates robustness and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Dashti A. Ali , Richard K. G. Do , William R. Jarnagin , Aras T. Asaad , Amber L. Simpson

We describe and analyze a numerical algorithm for computing the homology (Betti numbers and torsion coefficients) of real projective varieties. Here numerical means that the algorithm is numerically stable (in a sense to be made precise).…

Algebraic Geometry · Mathematics 2017-05-16 Felipe Cucker , Teresa Krick , Michael Shub

Proteins are the most important biomolecules for living organisms. The understanding of protein structure, function, dynamics and transport is one of most challenging tasks in biological science. In the present work, persistent homology is,…

Biomolecules · Quantitative Biology 2014-12-10 Kelin Xia , Guo-Wei Wei

Persistent homology (PH) is one of the most popular methods in Topological Data Analysis. Even though PH has been used in many different types of applications, the reasons behind its success remain elusive; in particular, it is not known…

Algebraic Topology · Mathematics 2023-01-18 Renata Turkeš , Guido Montúfar , Nina Otter

Automation and reliability are the two main requirements when computers are applied in Life Sciences. In this paper we report on an application to neuron recognition, an important step in our long-term project of providing software systems…

Computer Vision and Pattern Recognition · Computer Science 2015-09-16 Jónathan Heras , Gadea Mata , Germán Cuesto , Julio Rubio , Miguel Morales

We propose a unified framework based on persistent homology (PH) to characterize both local and global structures in disordered systems. It can simultaneously generate local and global descriptors using the same algorithm and data…

Disordered Systems and Neural Networks · Physics 2025-11-03 An Wang , Li Zou

We introduce a consistent estimator for the homology (an algebraic structure representing connected components and cycles) of level sets of both density and regression functions. Our method is based on kernel estimation. We apply this…

Statistics Theory · Mathematics 2016-09-30 Omer Bobrowski , Sayan Mukherjee , Jonathan E. Taylor

A multicomplex structure is defined from an ordered lattice of multigraphs. This structure will help us to observe the features of Persistent Homology in this context, its interaction with the ordering and the repercussions of the process…

Algebraic Topology · Mathematics 2025-02-05 Joaquin Diaz Boils

We present a parallelizable algorithm for computing the persistent homology of a filtered chain complex. Our approach differs from the commonly used reduction algorithm by first computing persistence pairs within local chunks, then…

Algebraic Topology · Mathematics 2013-03-05 Ulrich Bauer , Michael Kerber , Jan Reininghaus

Persistent homology provides information about the lifetime of homology classes along a filtration of cell complexes. Persistence barcode is a graphical representation of such information. A filtration might be determined by time in a set…

Computer Vision and Pattern Recognition · Computer Science 2018-01-04 Rocio Gonzalez-Diaz , Maria-Jose Jimenez , Belen Medrano

Graph-based representations of point-cloud data are widely used in data science and machine learning, including epsilon-graphs that contain edges between pairs of data points that are nearer than epsilon and kNN-graphs that connect each…

Algebraic Topology · Mathematics 2022-06-13 Minh Quang Le , Dane Taylor

Topological accuracy in medical image segmentation is a highly important property for downstream applications such as network analysis and flow modeling in vessels or cell counting. Recently, significant methodological advancements have…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Alexander H. Berger , Nico Stucki , Laurin Lux , Vincent Buergin , Suprosanna Shit , Anna Banaszak , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

Through the use of examples, we explain one way in which applied topology has evolved since the birth of persistent homology in the early 2000s. The first applications of topology to data emphasized the global shape of a dataset, such as…

Algebraic Topology · Mathematics 2021-04-23 Henry Adams , Michael Moy

This work introduces a number of algebraic topology approaches, such as multicomponent persistent homology, multi-level persistent homology and electrostatic persistence for the representation, characterization, and description of small…

Quantitative Methods · Quantitative Biology 2018-02-07 Zixuan Cang , Lin Mu , Guowei Wei

Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Bo Wen , Haochen Zhang , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

We study the global and local topological properties of multi-lepton patterns reconstructed at the detectors. We investigate the sensitivity of Forman Ricci curvature distributions and persistent homology features to kinematic cuts,…

High Energy Physics - Phenomenology · Physics 2024-08-01 Jyotiranjan Beuria

Persistent homology is a methodology central to topological data analysis that extracts and summarizes the topological features within a dataset as a persistence diagram; it has recently gained much popularity from its myriad successful…

Applications · Statistics 2023-11-28 Yueqi Cao , Prudence Leung , Anthea Monod

The theory of multidimensional persistent homology was initially developed in the discrete setting, and involved the study of simplicial complexes filtered through an ordering of the simplices. Later, stability properties of…

Computational Geometry · Computer Science 2013-03-28 Niccolò Cavazza , Marc Ethier , Patrizio Frosini , Tomasz Kaczynski , Claudia Landi
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