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In a previous study, dissipative particle dynamics simulation was used to qualitatively clarify the phase diagram of the amphiphilic molecule hexaethylene glycol dodecyl ether (C12E6). In the present study, the hydrophilicity dependence of…

Soft Condensed Matter · Physics 2015-06-25 Hiroaki Nakamura , Yuichi Tamura

The nature of electrostatic interactions involving polyanions modulate the properties of both synthetic and biological macromolecules. Although intensely studied for decades the interplay of many length scales has prevented a complete…

Soft Condensed Matter · Physics 2011-03-11 Ngo Minh Toan , Bae-Yeun Ha , D. Thirumalai

We propose a framework to study the spatio-temporal evolution of liquid-liquid phase separation of weak polyelectrolytes in ionic solutions. Unlike strong polyelectrolytes, which carry a fixed charge, the charge state of weak…

Soft Condensed Matter · Physics 2025-03-19 Giulia Laura Celora , Ralf Blossey , Andreas Munch , Barbara Wagner

Phase separation drives the formation of biomolecular condensates in cells, which comprise many components and sometimes possess multiple phases. The equilibrium physics of phase separation is well understood, but many components in…

Soft Condensed Matter · Physics 2025-08-14 Yicheng Qiang , Chengjie Luo , David Zwicker

Phase separations in strongly coupled fine particles in plasmas are discussed and two-component mixtures are simulated by molecular dynamics with the background plasma being treated as continuum. The system size of laboratory experiments is…

Plasma Physics · Physics 2024-05-24 Hiroo Totsuji

The formation of coacervates through phase separation of oppositely charged polyelectrolytes (PEs) is critical for understanding biological condensates and developing responsive materials. Traditionally, coacervates are viewed as spherical…

Soft Condensed Matter · Physics 2024-12-23 Jiaxing Yuan , Hajime Tanaka

Understanding the behavior of charged complex fluids is crucial for a plethora of important industrial, technological, and medical applications. Using coarse-grained molecular dynamics simulations, here we investigate the properties of a…

Soft Condensed Matter · Physics 2022-08-04 Debarshee Bagchi

We investigated the effect of charge on the membrane morphology of giant unilamellar vesicles (GUVs) composed of various mixtures containing charged lipids. We observed the membrane morphologies by fluorescent and confocal laser microscopy…

Soft Condensed Matter · Physics 2016-01-08 Hiroki Himeno , Hiroaki Ito , Yuji Higuchi , Tsutomu Hamada , Naofumi Shimokawa , Masahiro Takagi

Phase separation plays an role in determining the self-assembly of biological and soft-matter systems. In biological systems, liquid-liquid phase separation inside a cell leads to the formation of various macromolecular aggregates. The…

Soft Condensed Matter · Physics 2024-03-26 Tanmay Biswas , Gerhard Kahl , Gaurav P. Shrivastav

Accurate identification of chemical phases associated with the electrode and solid electrolyte interphase (SEI) is critical for understanding and controlling interfacial degradation mechanisms in lithium containing battery systems. To study…

Materials Science · Physics 2018-09-19 Kevin N. Wood , Glenn Teeter

Demixing of multicomponent biomolecular systems via liquid-liquid phase separation (LLPS) has emerged as a potentially unifying mechanism governing the formation of several membrane-less intracellular organelles ("condensates"), both in the…

Soft Condensed Matter · Physics 2022-10-04 Pierre Ronceray , Sheng Mao , Andrej Košmrlj , Mikko P. Haataja

Biomolecular condensates in cells are often rich in catalytically-active enzymes. This is particularly true in the case of the large enzymatic complexes known as metabolons, which contain different enzymes that participate in the same…

Subcellular Processes · Quantitative Biology 2021-10-20 Vincent Ouazan-Reboul , Jaime Agudo-Canalejo , Ramin Golestanian

We propose a model describing the phase behavior of two-component membranes consisting of binary mixtures of electrically charged and neutral lipids. We take into account the structural phase transition (main-transition) of the hydrocarbon…

Soft Condensed Matter · Physics 2016-07-11 Naofumi Shimokawa , Hiroki Himeno , Tsutomu Hamada , Masahiro Takagi , Shigeyuki Komura , David Andelman

Differences in activities in colloidal particles are sufficient to drive phase separation between active and passive (or less active) particles, even if they have only excluded volume interactions. In this paper, we study the phase…

Soft Condensed Matter · Physics 2020-05-27 Efe Ilker , Jean-François Joanny

We study numerically a model of non-aligning self-propelled particles interacting through steric repulsion, which was recently shown to exhibit active phase separation in two dimensions in the absence of any attractive interaction or…

Soft Condensed Matter · Physics 2014-06-03 Yaouen Fily , Silke Henkes , M. Cristina Marchetti

Much work has been devoted to analysing thermodynamic models for solid dispersions with a view to identifying regions in the phase diagram where amorphous phase separation or drug recrystallization can occur. However, detailed partial…

Soft Condensed Matter · Physics 2020-06-26 Martin Meere , Giuseppe Pontrelli , Sean McGinty

Phase separation of multicomponent liquid mixtures plays an integral part in many processes ranging from industry to cellular biology. In many cases the morphology of coexisting phases is crucially linked to the function of the separated…

Soft Condensed Matter · Physics 2020-11-25 Sheng Mao , Milena S. Chakraverti-Wuerthwein , Hunter Gaudio , Andrej Kosmrlj

Many materials containing colloids or polymers are polydisperse: They comprise particles with properties (such as particle diameter, charge, or polymer chain length) that depend continuously on one or several parameters. This review…

Soft Condensed Matter · Physics 2007-05-23 Peter Sollich

Cells and cellular organelles are encapsulated by nanometrically thin membranes whose main component is a lipid bilayer. In the presence of electric fields, the ion-impermeable lipid bilayer acts as a capacitor and supports a potential…

Soft Condensed Matter · Physics 2025-02-18 Shuozhen Zhao , Bhavya Balu , Zongxin Yu , Michael J. Miksis , Petia M. Vlahovska

Phase separation is the thermodynamic process that explains how droplets form in multicomponent fluids. These droplets can provide controlled compartments to localize chemical reactions, and reactions can also affect the droplets' dynamics.…

Soft Condensed Matter · Physics 2022-09-02 David Zwicker
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