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To understand biological intelligence we need to map neuronal networks in vertebrate brains. Mapping mesoscale neural circuitry is done using injections of tracers that label groups of neurons whose axons project to different brain regions.…

Neurons and Cognition · Quantitative Biology 2025-05-13 Samik Banerjee , Caleb Stam , Daniel J. Tward , Steven Savoia , Yusu Wang , Partha P. Mitra

Recent medical imaging studies have given rise to distinct but inter-related datasets corresponding to multiple experimental tasks or longitudinal visits. Standard scalar-on-image regression models that fit each dataset separately are not…

Methodology · Statistics 2022-01-21 Xin Ma , Suprateek Kundu

Data produced by resting-state functional Magnetic Resonance Imaging are widely used to infer brain functional connectivity networks. Such networks correlate neural signals to connect brain regions, which consist in groups of dependent…

Methodology · Statistics 2023-12-05 Hanâ Lbath , Alexander Petersen , Sophie Achard

Large-scale medical biobanks provide imaging data complemented by extensive tabular information, such as clinical measurements or demographics. However, this abundance of tabular attributes does not reflect real-world datasets, where only a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Marta Hasny , Laura Daza , Keno Bressem , Maxime Di Folco , Julia Schnabel

We study the intriguing connection between visual data, deep networks, and the brain. Our method creates a universal channel alignment by using brain voxel fMRI response prediction as the training objective. We discover that deep networks,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Huzheng Yang , James Gee , Jianbo Shi

Delineating the associations between images and a vector of covariates is of central interest in medical imaging studies. To tackle this problem of image response regression, we propose a novel nonparametric approach in the framework of…

Machine Learning · Statistics 2022-03-04 Daiwei Zhang , Lexin Li , Chandra Sripada , Jian Kang

Fully convolutional deep neural networks have been asserted to be fast and precise frameworks with great potential in image segmentation. One of the major challenges in training such networks raises when data is unbalanced, which is common…

Computer Vision and Pattern Recognition · Computer Science 2018-12-17 Seyed Raein Hashemi , Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Sanjay P. Prabhu , Simon K. Warfield , Ali Gholipour

Resting-state brain functional connectivity quantifies the synchrony between activity patterns of different brain regions. In functional magnetic resonance imaging (fMRI), each region comprises a set of spatially contiguous voxels at which…

Methodology · Statistics 2025-11-07 Ruobin Liu , Chao Zhang , Chau Tran , Sophie Achard , Wendy Meiring , Alexander Petersen

Foundation models are emerging as a powerful paradigm for fMRI analysis, but current approaches face a dual bottleneck of data- and training-efficiency. Atlas-based methods aggregate voxel signals into fixed regions of interest, reducing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Mo Wang , Junfeng Xia , Wenhao Ye , Enyu Liu , Kaining Peng , Jianfeng Feng , Quanying Liu , Hongkai Wen

Representational similarity metrics typically force all units to be matched, making them susceptible to noise and outliers common in neural representations. We extend the soft-matching distance to a partial optimal transport setting that…

Machine Learning · Computer Science 2026-02-24 Chaitanya Kapoor , Alex H. Williams , Meenakshi Khosla

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

Connectivity information derived from diffusion-weighted magnetic resonance images~(DW-MRIs) plays an important role in studying human subcortical gray matter structures. However, due to the $O(N^2)$ complexity of computing the connectivity…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Zhangxing Bian , Muhan Shao , Jiachen Zhuo , Rao P. Gullapalli , Aaron Carass , Jerry L. Prince

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

Automatic 3D neuron reconstruction is critical for analysing the morphology and functionality of neurons in brain circuit activities. However, the performance of existing tracing algorithms is hinged by the low image quality. Recently, a…

Image and Video Processing · Electrical Eng. & Systems 2021-09-17 Heng Wang , Chaoyi Zhang , Jianhui Yu , Yang Song , Siqi Liu , Wojciech Chrzanowski , Weidong Cai

In the setting of clinical imaging, differences in between vendors, hospitals and sequences can yield highly inhomogeneous imaging data. In MRI in particular, voxel dimension, slice spacing and acquisition plane can vary substantially. For…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Ivan Diaz , Florin Scherer , Yanik Berli , Roland Wiest , Helly Hammer , Robert Hoepner , Alejandro Leon Betancourt , Piotr Radojewski , Richard McKinley

Voxel-based lesion-symptom mapping (VLSM) is a major method for studying brain-behavior relationships that leverages modern neuroimaging analysis techniques to build on the classic approach of examining the relationship between location of…

Applications · Statistics 2016-06-03 Daniel Mirman , Jon-Frederick Landrigan , Spiro Kokolis , Sean Verillo , Casey Ferrara

Visual saliency is a fundamental problem in both cognitive and computational sciences, including computer vision. In this CVPR 2015 paper, we discover that a high-quality visual saliency model can be trained with multiscale features…

Computer Vision and Pattern Recognition · Computer Science 2015-04-13 Guanbin Li , Yizhou Yu

Attributed network embedding aims to learn low-dimensional vector representations for nodes in a network, where each node contains rich attributes/features describing node content. Because network topology structure and node attributes…

Social and Information Networks · Computer Science 2018-10-17 Daokun Zhang , Jie Yin , Xingquan Zhu , Chengqi Zhang

One of the fundamental challenges in supervised learning for multimodal image registration is the lack of ground-truth for voxel-level spatial correspondence. This work describes a method to infer voxel-level transformation from…