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Both evolution and ecology have long been concerned with the impact of variable environmental conditions on observed levels of genetic diversity within and between species. We model the evolution of a quantitative trait under selection that…

Populations and Evolution · Quantitative Biology 2014-11-17 Hannes Svardal , Claus Rueffler , Joachim Hermisson

We study the fixation and stationary behavior of the Lambda-Wright-Fisher process with parent-independent mutation and finitely many types, a jump-diffusion model for allele frequency dynamics in large populations with potentially large…

Probability · Mathematics 2025-09-19 Airam Blancas , Adrián González Casanova , Sebastian Hummel , Sandra Palau

We introduce a new Wright-Fisher type model for seed banks incorporating "simultaneous switching", which is motivated by recent work on microbial dormancy. We show that the simultaneous switching mechanism leads to a new jump-diffusion…

Populations and Evolution · Quantitative Biology 2018-12-24 Jochen Blath , Adrián González Casanova , Noemi Kurt , Maite Wilke-Berenguer

Consider a two-type Moran population of size $N$ with selection and mutation, where the selective advantage of the fit individuals is amplified at extreme environmental conditions. Assume selection and mutation are weak with respect to $N$,…

Probability · Mathematics 2023-04-26 Fernando Cordero , Grégoire Véchambre

We study the long-time behavior of solutions to a model of sexual populations structured in phenotypes. The model features a nonlinear integral reproduction operator derived from the Fisher infinitesimal operator and a trait-dependent…

Analysis of PDEs · Mathematics 2024-12-24 Amic Frouvelle , Cécile Taing

A question in evolutionary biology is why the number of males is approximately equal to that of females in many species, and Fisher's theory of equal investment answers that it is the evolutionarily stable state. The Fisherian mechanism can…

Populations and Evolution · Quantitative Biology 2019-02-05 Minjae Kim , Hyeong-Chai Jeong , Seung Ki Baek

The purpose of this Note is twofold: First, we introduce the general formalism of evolutionary genetics dynamics involving fitnesses, under both the deterministic and stochastic setups, and chiefly in discrete-time. In the process, we…

Quantitative Methods · Quantitative Biology 2015-05-14 Thierry Huillet

Genetically identical cells in the same population can take on phenotypically variable states, leading to differentiated responses to external signals, such as nutrients and drug-induced stress. Many models and experiments have focused on a…

Molecular Networks · Quantitative Biology 2015-04-28 Thierry Mora , Aleksandra M. Walczak

This article is a presentation of specific recent results describing scaling limits of individual-based models. Thanks to them, we wish to relate the time-scales typical of demographic dynamics and natural selection to the parameters of the…

Probability · Mathematics 2023-08-01 Aurélien Velleret

We introduce a new class of stochastic partial differential equations (SPDEs) with seed bank modeling the spread of a beneficial allele in a spatial population where individuals may switch between an active and a dormant state.…

Probability · Mathematics 2021-11-12 Jochen Blath , Matthias Hammer , Florian Nie

More than 95% of the crop genetic erosion articles analyzed in [9] reported changes in diversity, with nearly 80% providing evidence of loss. The lack of diversity presents a severe risk to the security of global food systems. Without seed…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-11 Andrea Vitaletti

Fisher's fundamental theorem of natural selection states that the rate of change in a population's mean fitness equals its additive genetic variance in fitness. This implies that mean fitness should not decline in a constant environment,…

Populations and Evolution · Quantitative Biology 2025-08-18 Yun-Yun Yu , Cang Hui , Tian-Jiao Feng , Cong Li , Chao Wang , Yi Tao , Rui-Wu Wang

$\Lambda$-Wright--Fisher processes provide a robust framework to describe the type-frequency evolution of an infinite neutral population. We add a polynomial drift to the corresponding stochastic differential equation to incorporate…

Probability · Mathematics 2023-04-26 Fernando Cordero , Sebastian Hummel , Emmanuel Schertzer

Diffusion theory is a central tool of modern population genetics, yielding simple expressions for fixation probabilities and other quantities that are not easily derived from the underlying Wright-Fisher model. Unfortunately, the textbook…

Populations and Evolution · Quantitative Biology 2022-12-19 Camila Bräutigam , Matteo Smerlak

Evolutionary models for populations of constant size are frequently studied using the Moran model, the Wright-Fisher model, or their diffusion limits. When evolution is neutral, a random genealogy given through Kingman's coalescent is used…

Populations and Evolution · Quantitative Biology 2012-07-31 Peter Pfaffelhuber , Benedikt Vogt

We present a model for growth in a multi-species population. We consider two types evolving as a logistic branching process with mutation, where one of the types has a selective advantage, and are interested in the regime in which the…

Probability · Mathematics 2025-07-18 Marta Dai Pra , Julian Kern

Biological organisms have to cope with stochastic variations in both the external environment and the internal population dynamics. Theoretical studies and laboratory experiments suggest that population diversification could be an effective…

Populations and Evolution · Quantitative Biology 2017-09-13 BingKan Xue , Stanislas Leibler

Score-based diffusion models currently constitute the state of the art in continuous generative modeling. These methods are typically formulated via overdamped or underdamped Ornstein--Uhlenbeck-type stochastic differential equations, in…

Machine Learning · Computer Science 2025-12-22 Herlock Rahimi

A number of discrete time, finite population size models in genetics describing the dynamics of allele frequencies are known to converge (subject to suitable scaling) to a diffusion process in the infinite population limit, termed the…

Probability · Mathematics 2021-09-14 Jaromir Sant , Paul A. Jenkins , Jere Koskela , Dario Spano

A probability model is presented for the dynamics of mutation-selection balance in a haploid infinite-population infinite-sites setting sufficiently general to cover mutation-driven changes in full age-specific demographic schedules. The…

Populations and Evolution · Quantitative Biology 2007-05-23 David Steinsaltz , Steven N. Evans , Kenneth W. Wachter