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Recent advances in both theory and methods have created opportunities to simulate biomolecular processes more efficiently using adaptive ensemble simulations. Ensemble-based simulations are used widely to compute a number of individual…

Computational Engineering, Finance, and Science · Computer Science 2020-09-14 Vivek Balasubramanian , Travis Jensen , Matteo Turilli , Peter Kasson , Michael Shirts , Shantenu Jha

Biological impedance (BioZ) is an information-packed modality that allows for non-invasive monitoring of health and emotional state. Currently, most research involving tissue impedance is based on bulky or fixed-purpose hardware, which…

Extracellular matrix (ECM) remodeling is central to a wide variety of healthy and diseased tissue processes. Unfortunately, predicting ECM remodeling under various chemical and mechanical conditions has proven to be excessively challenging,…

Molecular Networks · Quantitative Biology 2026-05-26 Hasi Hays , William J. Richardson

Research on fetal phonocardiogram (fPCG) is challenged by the limited number of abdominal recordings, substantial maternal interference, and marked transmissioninduced signal attenuation that complicate reproducible benchmarking. We present…

Signal Processing · Electrical Eng. & Systems 2026-01-26 Yingtong Zhou , Yiang Zhou , Zhengxian Qu , Kang Liu , Ting Tan

Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Fanwei Kong , Aaron Brown , Michael Loecher , Perry S. Choi , Lei Shi , Michael Ma , Daniel B. Ennis , Alison Marsden

WavePacket is an open-source program package for numerical simulations in quantum dynamics. Building on the previous Part I [Comp. Phys. Comm. 213, 223-234 (2017)] and Part II [Comp. Phys. Comm. 228, 229-244 (2018)] which dealt with quantum…

Computational Physics · Physics 2023-02-09 Burkhard Schmidt , Rupert Klein , Leonardo Cancissu Araujo

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are an effective tool for studying cardiac function and disease, and hold promise for screening drug effects on human tissue. Changes to motion patterns in these cells…

Tissues and Organs · Quantitative Biology 2024-07-09 Henrik Finsberg , Verena Charwat , Kevin Healy , Samuel Wall

Autonomous robots in endovascular operations have the potential to navigate circulatory systems safely and reliably while decreasing the susceptibility to human errors. However, there are numerous challenges involved with the process of…

The stochastic simulation of biological systems is an increasingly popular technique in bioinformatics. It often is an enlightening technique, which may however result in being computational expensive. We discuss the main opportunities to…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-17 Marco Aldinucci , Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Massimo Torquati , Angelo Troina

Computational fluid dynamics (CFD) is an important tool for the simulation of the cardiovascular function and dysfunction. Due to the complexity of the anatomy, the transitional regime of blood flow in the heart, and the strong mutual…

Numerical simulations are ubiquitous in mathematics and computational science. Several industrial and clinical applications entail modeling complex multiphysics systems that evolve over a variety of spatial and temporal scales. This study…

Mathematical Software · Computer Science 2022-11-14 Pasquale Claudio Africa

The purpose of the Evaluating ECG capturing using sound-card of PC/Laptop is provided portable and low cost ECG monitoring system using laptop and mobile phones. There is no need to interface micro controller or any other device to transmit…

Other Computer Science · Computer Science 2014-02-18 Bhavikkumar Patel , Dhrumil Shah

The `equation-free toolbox' empowers the computer-assisted analysis of complex, multiscale systems. Its aim is to enable you to immediately use microscopic simulators to perform macro-scale system level tasks and analysis, because…

Mathematical Software · Computer Science 2020-04-08 John Maclean , J. E. Bunder , A. J. Roberts

The numerical simulation of cardiac electrophysiology is a highly challenging problem in scientific computing. The Bidomain system is the most complete mathematical model of cardiac bioelectrical activity. It consists of an elliptic and a…

Numerical Analysis · Mathematics 2023-11-27 Edoardo Centofanti , Simone Scacchi

Whole-body hemodynamics simulators, which model blood flow and pressure waveforms as functions of physiological parameters, are now essential tools for studying cardiovascular systems. However, solving the corresponding inverse problem of…

Over the past decades, hemodynamics simulators have steadily evolved and have become tools of choice for studying cardiovascular systems in-silico. While such tools are routinely used to simulate whole-body hemodynamics from physiological…

This paper introduces a shoebox room simulator able to systematically generate synthetic datasets of binaural room impulse responses (BRIRs) given an arbitrary set of head-related transfer functions (HRTFs). The evaluation of machine…

Sound · Computer Science 2021-06-25 Roberto Barumerli , Daniele Bianchi , Michele Geronazzo , Federico Avanzini

Many cytoskeletal systems are now sufficiently well known to permit their precise quantitative modelling. Microtubule and actin filaments are well characterized, and the associated proteins are often known, as well as their abundance and…

Quantitative Methods · Quantitative Biology 2022-05-30 Carlos A. Lugo , Eashan Saikia , Francois Nedelec

MATI (Microstructural Analysis Toolbox for Imaging) is a versatile MATLAB-based toolbox that combines both simulation and data fitting capabilities for microstructural dMRI research. It provides a user-friendly, GUI-driven interface that…

This work describes the setup of an advanced technical infrastructure for collaborative software development (CDE) in large, distributed projects based on GitLab. We present its customization and extension, additional features and processes…

Software Engineering · Computer Science 2023-08-10 Felix Bach , Jochen Klar , Axel Loewe , Jorge Sánchez , Gunnar Seemann , Yung-Lin Huang , Robert Ulrich