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Direct detector device (DDD) cameras have revolutionized single particle electron cryomicroscopy (cryo-EM). In addition to an improved camera detective quantum efficiency, acquisition of DDD movies allows for correction of movement of the…

Quantitative Methods · Quantitative Biology 2015-11-23 John L. Rubinstein , Marcus A. Brubaker

Brain tumor classification using MRI images is critical in medical diagnostics, where early and accurate detection significantly impacts patient outcomes. While recent advancements in deep learning (DL), particularly CNNs, have shown…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Priyam Ganguly , Akhilbaran Ghosh

We consider the problem of depth estimation from a single monocular image in this work. It is a challenging task as no reliable depth cues are available, e.g., stereo correspondences, motions, etc. Previous efforts have been focusing on…

Computer Vision and Pattern Recognition · Computer Science 2015-10-01 Fayao Liu , Chunhua Shen , Guosheng Lin

Cryogenic Electron Tomography (CryoET) combined with sub-volume averaging (SVA) is the only imaging modality capable of resolving protein structures inside cells at molecular resolution. Particle picking, the task of localizing and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Linhan Wang , Jianwen Dou , Wang Li , Shengkun Wang , Zhiwu Xie , Chang-Tien Lu , Yinlin Chen

Mental task identification and classification using single/limited channel(s) electroencephalogram (EEG) signals in real-time play an important role in the design of portable brain-computer interface (BCI) and neurofeedback (NFB) systems.…

Signal Processing · Electrical Eng. & Systems 2022-05-18 Manali Saini , Udit Satija , Madhur Deo Upadhayay

Cryo-electron microscopy (cryo-EM) has become a tool of fundamental importance in structural biology, helping us understand the basic building blocks of life. The algorithmic challenge of cryo-EM is to jointly estimate the unknown 3D poses…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Axel Levy , Frédéric Poitevin , Julien Martel , Youssef Nashed , Ariana Peck , Nina Miolane , Daniel Ratner , Mike Dunne , Gordon Wetzstein

We revisit the topic of common lines between projection images in single particle cryo-electron microscopy (cryo-EM). We derive a novel low-rank constraint on a certain $2n \times n$ matrix storing properly-scaled basis vectors for the…

Optimization and Control · Mathematics 2024-06-10 Tommi Muller , Adriana L. Duncan , Eric J. Verbeke , Joe Kileel

Single particle cryogenic electron microscopy (cryo-EM) is an imaging technique capable of recovering the high-resolution 3-D structure of biological macromolecules from many noisy and randomly oriented projection images. One notable…

Biomolecules · Quantitative Biology 2024-01-30 Andy Zhang , Oscar Mickelin , Joe Kileel , Eric J. Verbeke , Nicholas F. Marshall , Marc Aurèle Gilles , Amit Singer

In this research work, we have demonstrated the application of Mask-RCNN (Regional Convolutional Neural Network), a deep-learning algorithm for computer vision and specifically object detection, to semiconductor defect inspection domain.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-07 Bappaditya Dey , Enrique Dehaerne , Kasem Khalil , Sandip Halder , Philippe Leray , Magdy A. Bayoumi

Differential dynamic microscopy (DDM) typically relies on movies containing hundreds or thousands of frames to accurately quantify motion in soft matter systems. Using movies much shorter in duration produces noisier and less accurate…

Soft Condensed Matter · Physics 2024-11-05 Gildardo Martinez , Justin Siu , Steven Dang , Dylan Gage , Emma Kao , Juan Carlos Avila , Ruilin You , Ryan McGorty

State-of-the-art electron microscopes such as scanning electron microscopes (SEM), scanning transmission electron microscopes (STEM) and transmission electron microscopes (TEM) have become increasingly sophisticated. However, the quality of…

Computational Physics · Physics 2023-03-31 I. Lobato , T. Friedrich , S. Van Aert

Recently, deep convolutional neural networks have shown good results for image recognition. In this paper, we use convolutional neural networks with a finder module, which discovers the important region for recognition and extracts that…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 Yusei Miura , Tetsuya Sakurai , Claus Aranha , Toshiya Senda , Ryuichi Kato , Yusuke Yamada

Computed tomography (CT) can capture volumes large enough to measure a statistically meaningful number of micron-sized particles with a sufficiently good resolution to allow for the analysis of individual particles. However, the development…

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ha Anh Vu

Cryo-electron tomography (cryo-ET) has emerged as a powerful technique for imaging macromolecular complexes in their near-native states. However, the localization of 3D particles in cellular environments still presents a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Gokul Adethya , Bhanu Pratyush Mantha , Tianyang Wang , Xingjian Li , Min Xu

In a lot of scientific problems, there is the need to generate data through the running of an extensive number of experiments. Further, some tasks require constant human intervention. We consider the problem of crack detection in steel…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Chinmay Makarand Pimpalkhare , D. N. Pawaskar

We propose a new method for the discrimination of sub-micron nuclear recoil tracks from an instrumental background in fine-grain nuclear emulsions used in the directional dark matter search. The proposed method uses a 3D Convolutional…

High Energy Physics - Experiment · Physics 2022-02-17 Artem Golovatiuk , Andrey Ustyuzhanin , Andrey Alexandrov , Giovanni De Lellis

Macromolecules change their shape (conformation) in the process of carrying out their functions. The imaging by cryo-electron microscopy of rapidly-frozen, individual copies of macromolecules (single particles) is a powerful and general…

Biomolecules · Quantitative Biology 2022-11-22 Bogdan Toader , Fred J. Sigworth , Roy R. Lederman

Although deep encoder-decoder networks have achieved astonishing performance for mitochondria segmentation from electron microscopy (EM) images, they still produce coarse segmentations with lots of discontinuities and false positives.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-30 Zhimin Yuan , Jiajin Yi , Zhengrong Luo , Zhongdao Jia , Jialin Peng

Deep learning with a convolutional neural network (CNN) has been proved to be very effective in feature extraction and representation of images. For image classification problems, this work aim at finding which classifier is more…

Machine Learning · Computer Science 2015-06-09 Lei Zhang , David Zhang
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