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The dispersal of cells from an initially constrained location is a crucial aspect of many physiological phenomena ranging from morphogenesis to tumour spreading. In such processes, the way cell-cell interactions impact the motion of single…

We introduce a class of partial differential equations on metric graphs associated with mixed evolution: on some edges we consider diffusion processes, on other ones transport phenomena. This yields a system of equations with possibly…

Analysis of PDEs · Mathematics 2021-03-29 Amru Hussein , Delio Mugnolo

We investigate a recently proposed cross-diffusion system modelling the growth of gliobastoma taking into account size exclusion both in the migration and proliferation process. In addition to degenerate nonlinear cross-diffusion the model…

Analysis of PDEs · Mathematics 2017-10-12 Martin Burger , Patricia Friele , Jan-Frederik Pietschmann

We present a general theoretical framework to discuss mechanisms of morphogen transport and gradient formation in a cell layer. Trafficking events on the cellular scale lead to transport on larger scales. We discuss in particular the case…

Other Quantitative Biology · Quantitative Biology 2015-06-26 T. Bollenbach , K. Kruse , P. Pantazis , M. Gonzalez-Gaitan , F. Julicher

Deep generative models learn the data distribution, which is concentrated on a low-dimensional manifold. The geometric analysis of distribution transformation provides a better understanding of data structure and enables a variety of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Junhao Chen , Manyi Li , Zherong Pan , Xifeng Gao , Changhe Tu

We study a stochastic epidemic model consisting of elements (organisms in a community or cells in tissue) with fixed positions, in which damage or disease is transmitted by diffusing agents ("signals") emitted by infected individuals. The…

Populations and Evolution · Quantitative Biology 2015-06-05 Fernando P. Faria , Ronald Dickman

The population dynamics that evolves in the radial symmetric geometry is investigated. The nonlinear reaction-diffusion model, which depends on population density, is employed as the governing equation for this system. The approximate…

Biological Physics · Physics 2014-01-17 Waipot Ngamsaad

Most transport theorems---that is, a formula for the rate of change of an integral in which both the integrand and domain of integration depend on time---involve domains that evolve according to a flow map. Such domains are said to be…

Differential Geometry · Mathematics 2019-05-01 Brian Seguin

A study of time homogeneous, real valued Markov processes with a special property and a non-atomic initial distribution is provided. The new notion of a function of evolution of distribution which determines the dependency between one…

Probability · Mathematics 2022-07-04 Tomasz Bielecki , Jacek Jakubowski , Maciej Wiśniewolski

We analyze a one dimensional version of a model of morphogen transport, a biological process governing cell differentiation. The model was proposed by Hufnagel et al. to describe the forming of morphogen gradient in the wing imaginal disc…

Analysis of PDEs · Mathematics 2014-12-17 Marcin Malogrosz

We expand on a recent study of a lattice model of interacting particles [Phys. Rev. Lett. 111, 110601 (2013)]. The adsorption isotherm and equilibrium fluctuations in particle number are discussed as a function of the interaction. Their…

Statistical Mechanics · Physics 2014-11-20 T. Becker , K. Nelissen , B. Cleuren , B. Partoens , C. Van den Broeck

A molecule traveling in a realistic propagation environment can experience stochastic interactions with other molecules and the environment boundary. The statistical behavior of some isolated phenomena, such as dilute unbounded molecular…

Chemical Physics · Physics 2015-05-20 Adam Noel , Karen C. Cheung , Robert Schober

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

Biological Physics · Physics 2022-07-13 T. N. Azevedo , L. G. Rizzi

Cells and organisms follow aligned structures in their environment, a process that can generate persistent migration paths. Kinetic transport equations are a popular modelling tool for describing biological movements at the mesoscopic…

Cell Behavior · Quantitative Biology 2021-01-13 Nadia Loy , Thomas Hillen , Kevin John Painter

We consider a macroscopic model for the growth of living tissues incorporating pressure-driven dispersal and pressure-modulated proliferation. Assuming a power-law relation between the mechanical pressure and the cell density, the model can…

Analysis of PDEs · Mathematics 2024-03-29 Tomasz Dębiec , Piotr Gwiazda , Błażej Miasojedow , Zuzanna Szymańska

Spreading processes on top of active dynamics provide a novel theoretical framework for capturing emerging collective behavior in living systems. I consider run-and-tumble dynamics coupled with coagulation/decoagulation reactions that lead…

Statistical Mechanics · Physics 2025-05-29 Matteo Paoluzzi

Recently, several experiments have demonstrated the existence of fractional diffusion in the neuronal transmission occurringin the Purkinje cells, whose malfunctioning is known to be related to the lack of voluntary coordination and the…

Analysis of PDEs · Mathematics 2018-05-01 Serena Dipierro , Enrico Valdinoci

Dispersion curves to a oscillatory reaction-diffusion system with the self-consistent flow have obtained by means of numerical calculations. The flow modulates the shape of dispersion curves and characteristics of traveling waves. The point…

patt-sol · Physics 2007-05-23 Hiroyasu Yamada , Toshiyuki Nakagaki

Diffusion processes are widespread in biological and chemical systems, where they play a fundamental role in the exchange of substances at the cellular level and in determining the rate of chemical reactions. Recently, the classical picture…

Soft Condensed Matter · Physics 2015-09-16 Roberto Cerbino , Yifei Sun , Aleksandar Donev , Alberto Vailati

We study a reaction-diffusion model posed on two distinct spatial scales that accounts for diffusion, aggregation, fragmentation, and deposition of populations of colloidal particles within a porous material. In this model, the macroscopic…

Analysis of PDEs · Mathematics 2026-04-14 Christos Nikolopoulos , Michael Eden , Adrian Muntean