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Introduction: Kidney function is reported using estimates of glomerular filtration rate (eGFR). However, eGFR values are recorded without reference to the creatinine (SCr) assays used to derive them, and newer assays were introduced at…

Quantitative Methods · Quantitative Biology 2014-09-05 Norman Poh , Andrew McGovern , Simon de Lusignan

In order for clinicians to manage disease progression and make effective decisions about drug dosage, treatment regimens or scheduling follow up appointments, it is necessary to be able to identify both short and long-term trends in…

Quantitative Methods · Quantitative Biology 2016-12-06 Norman Poh , Simon Bull , Santosh Tirunagari , Nicholas Cole , Simon de Lusignan

Electrophysiological observation plays a major role in epilepsy evaluation. However, human interpretation of brain signals is subjective and prone to misdiagnosis. Automating this process, especially seizure detection relying on scalp-based…

Machine Learning · Computer Science 2018-07-06 David Ahmedt-Aristizabal , Clinton Fookes , Kien Nguyen , Sridha Sridharan

Chronic kidney disease (CKD) is a global health challenge characterized by progressive kidney function decline, often culminating in end-stage kidney disease (ESKD) and increased mortality. To address the limitations such as the extended…

Methodology · Statistics 2025-04-11 Tuo Wang , Yu Du

Ventricular Fibrillation (VF), one of the most dangerous arrhythmias, is responsible for sudden cardiac arrests. Thus, various algorithms have been developed to predict VF from Electrocardiogram (ECG), which is a binary classification…

Machine Learning · Computer Science 2019-03-13 Nabil Ibtehaz , M. Saifur Rahman , M. Sohel Rahman

Early recognition of abnormal rhythms in ECG signals is crucial for monitoring and diagnosing patients' cardiac conditions, increasing the success rate of the treatment. Classifying abnormal rhythms into exact categories is very challenging…

Machine Learning · Computer Science 2019-12-18 Jing Zhang , Jing Tian , Yang Cao , Yuxiang Yang , Xiaobin Xu

Despite the eminent successes of deep neural networks, many architectures are often hard to transfer to irregularly-sampled and asynchronous time series that commonly occur in real-world datasets, especially in healthcare applications. This…

Machine Learning · Computer Science 2020-09-16 Max Horn , Michael Moor , Christian Bock , Bastian Rieck , Karsten Borgwardt

We present a personalized and reliable prediction model for healthcare, which can provide individually tailored medical services such as diagnosis, disease treatment, and prevention. Our proposed framework targets at making personalized and…

Machine Learning · Statistics 2019-11-26 Ingyo Chung , Saehoon Kim , Juho Lee , Kwang Joon Kim , Sung Ju Hwang , Eunho Yang

Electrocardiogram (ECG), a technique for medical monitoring of cardiac activity, is an important method for identifying cardiovascular disease. However, analyzing the increasing quantity of ECG data consumes a lot of medical resources. This…

Signal Processing · Electrical Eng. & Systems 2022-10-13 Xinyao Hou , Shengmei Qin , Jianbo Su

Interpretation of electrocardiography (ECG) signals is required for diagnosing cardiac arrhythmia. Recently, machine learning techniques have been applied for automated computer-aided diagnosis. Machine learning tasks can be divided into…

In this work we introduce the lag irreversibility function as a method to assess time-irreversibility in discrete time series. It quantifies the degree of time-asymmetry for the joint probability function of the state variable under study…

Data Analysis, Statistics and Probability · Physics 2023-08-01 Nazul Merino Negrete , Cesar Maldonado , Raúl Salgado-García

Recent studies have demonstrated the diagnostic and prognostic values of global glomerulosclerosis (GGS) in IgA nephropathy, aging, and end-stage renal disease. However, the fine-grained quantitative analysis of multiple GGS subtypes (e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Yuzhe Lu , Haichun Yang , Zuhayr Asad , Zheyu Zhu , Tianyuan Yao , Jiachen Xu , Agnes B. Fogo , Yuankai Huo

Objective: Current resuscitation protocols require pausing chest compressions during cardiopulmonary resuscitation (CPR) to check for a pulse. However, pausing CPR during a pulseless rhythm can worsen patient outcome. Our objective is to…

Signal Processing · Electrical Eng. & Systems 2020-08-06 Diya Sashidhar , Heemun Kwok , Jason Coult , Jen Blackwood , Peter Kudenchuck , Shiv Bhandari , Thomas Rea , J. Nathan Kutz

The automatic classification of medical time series signals, such as electroencephalogram (EEG) and electrocardiogram (ECG), plays a pivotal role in clinical decision support and early detection of diseases. Although Transformer based…

Machine Learning · Computer Science 2025-09-22 Ming Hu , Jianfu Yin , Mingyu Dou , Yuqi Wang , Ruochen Dang , Siyi Liang , Feiyu Zhu , Cong Hu , Yao Wang , Bingliang Hu , Quan Wang

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

Objective: Gaussian Processes (GP)-based filters, which have been effectively used for various applications including electrocardiogram (ECG) filtering can be computationally demanding and the choice of their hyperparameters is typically ad…

Signal Processing · Electrical Eng. & Systems 2024-01-10 Mircea Dumitru , Qiao Li , Erick Andres Perez Alday , Ali Bahrami Rad , Gari D. Clifford , Reza Sameni

The electrocardiogram or ECG has been in use for over 100 years and remains the most widely performed diagnostic test to characterize cardiac structure and electrical activity. We hypothesized that parallel advances in computing power,…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Geoffrey H. Tison , Jeffrey Zhang , Francesca N. Delling , Rahul C. Deo

The traditional method of diagnosing heart disease on ECG signal is artificial observation. Some have tried to combine expertise and signal processing to classify ECG signal by heart disease type. However, the currency is not so sufficient…

Signal Processing · Electrical Eng. & Systems 2019-10-29 Jie Zhang , Bohao Li , Kexin Xiang , Xuegang Shi

Heart disease is one of the most common diseases causing morbidity and mortality. Electrocardiogram (ECG) has been widely used for diagnosing heart diseases for its simplicity and non-invasive property. Automatic ECG analyzing technologies…

Machine Learning · Computer Science 2019-08-28 Yang Liu , Runnan He , Kuanquan Wang , Qince Li , Qiang Sun , Na Zhao , Henggui Zhang

The automated analysis of medical time series, such as the electrocardiogram (ECG), electroencephalogram (EEG), pulse oximetry, etc, has the potential to serve as a valuable tool for diagnostic decisions, allowing for remote monitoring of…

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