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Collective oscillations and their suppression by external stimulation are analyzed in a large-scale neural network consisting of two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons. In the limit of…

Neurons and Cognition · Quantitative Biology 2021-07-14 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

Collective dynamics result from interactions among noisy dynamical components. Examples include heartbeats, circadian rhythms, and various pattern formations. Because of noise in each component, collective dynamics inevitably involve…

Biological Physics · Physics 2010-09-09 Naoki Masuda , Yoji Kawamura , Hiroshi Kori

Population rate or activity equations are the foundation of a common approach to modeling for neural networks. These equations provide mean field dynamics for the firing rate or activity of neurons within a network given some connectivity.…

Neurons and Cognition · Quantitative Biology 2009-05-15 Michael A. Buice , Jack D. Cowan , Carson C. Chow

Recurrent neural networks with balanced excitation and inhibition exhibit irregular asynchronous dynamics, which is fundamental for cortical computations. Classical balance mechanisms require strong external inputs to sustain finite firing…

Neurons and Cognition · Quantitative Biology 2025-10-21 David Angulo-Garcia , Alessandro Torcini

There is consensus in the current literature that stable states of asynchronous irregular spiking activity require (i) large networks of 10 000 or more neurons and (ii) external background activity or pacemaker neurons. Yet already in 1963,…

Neurons and Cognition · Quantitative Biology 2013-11-07 Marc-Oliver Gewaltig

Networked dynamical systems, i.e., systems of dynamical units coupled via nontrivial interaction topologies, constitute models of broad classes of complex systems, ranging from gene regulatory and metabolic circuits in our cells to…

Adaptation and Self-Organizing Systems · Physics 2024-03-12 Xiaozhu Zhang , Marc Timme

Recent experimental advances are producing an avalanche of data on both neural connectivity and neural activity. To take full advantage of these two emerging datasets we need a framework that links them, revealing how collective neural…

Neurons and Cognition · Quantitative Biology 2020-02-27 Gabriel Koch Ocker , Krešimir Josić , Eric Shea-Brown , Michael A. Buice

Neural network dynamics emerge from the interaction of spiking cells. One way to formulate the problem is through a theoretical framework inspired by ideas coming from statistical physics, the so-called mean-field theory. In this document,…

Analysis of PDEs · Mathematics 2020-11-11 Grégory Dumont , Pierre Gabriel

We study the spike statistics of neurons in a network with dynamically balanced excitation and inhibition. Our model, intended to represent a generic cortical column, comprises randomly connected excitatory and inhibitory leaky…

Neurons and Cognition · Quantitative Biology 2007-05-23 Alexander Lerchner , Cristina Ursta , John Hertz , Mandana Ahmadi , Pauline Ruffiot

A stochastic model of excitatory and inhibitory interactions which bears universality traits is introduced and studied. The endogenous component of noise, stemming from finite size corrections, drives robust inter-nodes correlations, that…

Disordered Systems and Neural Networks · Physics 2017-08-16 Clement Zankoc , Duccio Fanelli , Francesco Ginelli , Roberto Livi

The population activity of random networks of excitatory and inhibitory leaky integrate-and-fire (LIF) neurons has been studied extensively. In particular, a state of asynchronous activity with low firing rates and low pairwise correlations…

Neurons and Cognition · Quantitative Biology 2015-06-03 Volker Pernice , Benjamin Staude , Stefano Cardanobile , Stefan Rotter

The theory of Balanced Neural Networks is a very popular explanation for the high degree of variability and stochasticity in the brain's activity. Roughly speaking, it entails that typical neurons receive many excitatory and inhibitory…

Probability · Mathematics 2025-05-27 James MacLaurin , Pedro Vilanova

Complexity in the temporal organization of neural systems may be a reflection of the diversity of its neural constituents. These constituents, excitatory and inhibitory neurons, comprise an invariant ratio in vivo and form the substrate for…

Neurons and Cognition · Quantitative Biology 2015-05-18 Xin Chen , Rhonda Dzakpasu

Various functions of a network of excitable units can be enhanced if the network is in the `critical regime', where excitations are, on average, neither damped nor amplified. An important question is how can such networks self-organize to…

Disordered Systems and Neural Networks · Physics 2020-02-19 Yogesh S. Virkar , Juan G. Restrepo , Woodrow L. Shew , Edward Ott

Biological neural networks can operate in qualitatively distinct dynamical regimes, and transitions between these regimes are thought to underlie changes in computation and behavior. The seminal work of Sompolinsky, Crisanti, and Sommers…

Disordered Systems and Neural Networks · Physics 2026-05-15 Carles Martorell , Rubén Calvo , Alessia Annibale , Miguel A. Muñoz

Despite the huge number of neurons composing a brain network, ongoing activity of local cell assemblies composing cortical columns is intrinsically stochastic. Fluctuations in their instantaneous rate of spike firing $\nu(t)$ scale with the…

Neurons and Cognition · Quantitative Biology 2024-04-15 Gianni V. Vinci , Roberto Benzi , Maurizio Mattia

Research on network mechanisms and coding properties of grid cells assume that the firing rate of a grid cell in each of its fields is the same. Furthermore, proposed network models predict spatial regularities in the firing of inhibitory…

Neurons and Cognition · Quantitative Biology 2017-01-19 Benjamin Dunn , Daniel Wennberg , Ziwei Huang , Yasser Roudi

Firing patterns in the central nervous system often exhibit strong temporal irregularity and heterogeneity in their time averaged response properties. Previous studies suggested that these properties are outcome of an intrinsic chaotic…

Disordered Systems and Neural Networks · Physics 2015-11-25 Jonathan Kadmon , Haim Sompolinsky

A certain degree of inhibition is a common trait of dynamical networks in nature, ranging from neuronal and biochemical networks, to social and technological networks. We study here the role of inhibition in a representative dynamical…

Adaptation and Self-Organizing Systems · Physics 2017-12-27 Joao Pinheiro Neto , Marcus A. M. de Aguiar , José A. Brum , Stefan Bornholdt

In computer simulations of spiking neural networks, often it is assumed that every two neurons of the network are connected by a probability of 2\%, 20\% of neurons are inhibitory and 80\% are excitatory. These common values are based on…

Neurons and Cognition · Quantitative Biology 2015-03-06 Hamed Seyed-allaei