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Cell motility in viscous fluids is ubiquitous and affects many biological processes, including reproduction, infection, and the marine life ecosystem. Here we review the biophysical and mechanical principles of locomotion at the small…

Soft Condensed Matter · Physics 2009-09-16 Eric Lauga , Thomas R. Powers

Swimming micro-organisms such as bacteria or spermatozoa are typically found in dense suspensions, and exhibit collective modes of locomotion qualitatively different from that displayed by isolated cells. In the dilute limit where…

Biological Physics · Physics 2010-05-02 Sebastien Michelin , Eric Lauga

A variety of swimming microorganisms, called ciliates, exploit the bending of a large number of small and densely-packed organelles, termed cilia, in order to propel themselves in a viscous fluid. We consider a spherical envelope model for…

Fluid Dynamics · Physics 2011-08-30 Sebastien Michelin , Eric Lauga

Toxoplasma gondii is the causative agent responsible for toxoplasmosis and serves as one of the most common parasites in the world. For a successful lytic cycle, T. gondii must traverse biological barriers in order to invade host cells, and…

Quantitative Methods · Quantitative Biology 2017-08-21 Mojtaba Sedigh Fazli , Stephen Andrew Vella , Silvia N. J. Moreno , Shannon Quinn

Many biological microswimmers locomote by periodically beating the densely-packed cilia on their cell surface in a wave-like fashion. While the swimming mechanisms of ciliated microswimmers have been extensively studied both from the…

Soft Condensed Matter · Physics 2023-06-22 Hanliang Guo , Hai Zhu , Ruowen Liu , Marc Bonnet , Shravan Veerapaneni

Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves". These are beautiful examples of emergent dynamics in biology, and are essential for…

Soft Condensed Matter · Physics 2016-04-20 Nicolas Bruot , Pietro Cicuta

There is increasing evidence that mammalian cells not only crawl on substrates but can also swim in fluids. To elucidate the mechanisms of the onset of motility of cells in suspension, a model which couples actin and myosin kinetics to…

Biological Physics · Physics 2019-09-18 Alexander Farutin , Jocelyn Etienne , Chaouqi Misbah , Pierre Recho

Hypothesis: Bacterial contamination of surfaces poses a major threat to public health. Designing effective antibacterial or self-cleaning surfaces requires understanding how bacteria-laden droplets interact with solid substrates and how…

Soft Condensed Matter · Physics 2025-10-29 Sirshendu Misra , Sudip Shyam , Priyam Chakraborty , Sushanta K. Mitra

Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag…

Quantitative Methods · Quantitative Biology 2013-09-06 Thomas D. Montenegro-Johnson , Andrew A. Smith , David J. Smith , Daniel Loghin , John R. Blake

We analyse a simple 'Stokesian squirmer' model for the enhanced mixing due to swimming micro-organisms. The model is based on a calculation of Thiffeault & Childress [Physics Letters A, 374, 3487 (2010), arXiv:0911.5511], where fluid…

Fluid Dynamics · Physics 2013-09-24 Zhi Lin , Jean-Luc Thiffeault , Stephen Childress

We report on a diffusive analysis of the motion of flagellate protozoa species. These parasites are the etiological agents of neglected tropical diseases: leishmaniasis caused by Leishmania amazonensis and Leishmania braziliensis, African…

Biological Physics · Physics 2016-03-28 L. G. A. Alves , D. B. Scariot , R. R. Guimarães , C. V. Nakamura , R. S. Mendes , H. V. Ribeiro

Microswimmers often use chirality to generate translational movement from rotation motion, exhibiting distinct behaviors in complex fluids compared to simple Newtonian fluids. However, the underlying mechanism remains incompletely…

Soft Condensed Matter · Physics 2024-11-08 Takuya Kobayashi , John J. Molina , Ryoichi Yamamoto

We present a model for host-parasite dynamics which incorporates both vertical and horizontal transmission as well as spatial structure. Our model consists of stacked contact processes (CP), where the dynamics of the host is a simple CP on…

Biological Physics · Physics 2015-05-26 Steven J. Court , Richard A. Blythe , Rosalind J. Allen

Transport phenomena of microswimmers in fluid flows play a crucial role in various biological processes, including bioconvection and cell sorting. In this paper, we investigate the dispersion behavior of chiral microswimmers in a simple…

Fluid Dynamics · Physics 2024-03-14 Keito Ogawa , Kenta Ishimoto

Recent experiments have shown that the nematode {\it T. aceti} can assemble into collectively undulating groups at the edge of fluid drops. This coordinated state consists of metachronal waves and drives fluid circulation inside the drop.…

Cellular appendages such as cilia and flagella represent universal tools enabling cells and microbes, among other essential functionalities, to propel themselves in diverse environments. In its planktonic, i.e. freely swimming, state the…

Swimming cells and microorganisms must often move though complex fluids that contain an immersed microstructure such as polymer molecules, or filaments. In many important biological processes, such as mammalian reproduction and bacterial…

Fluid Dynamics · Physics 2018-08-06 Arshad Kamal , Eric E Keaveny

Bacteria commonly live in structured communities that affect human health and influence ecological systems. Heterogeneous populations, such as motile and non-motile populations, often coexist in bacteria communities. Motile subpopulations…

Biological Physics · Physics 2019-06-19 Haoran Xu , Justas Dauparas , Debasish Das , Eric Lauga , Yilin Wu

Malaria is a mosquito-borne disease with a devastating global impact. Plasmodium vivax is a major cause of human malaria beyond sub-Saharan Africa. Relapsing infections, driven by a reservoir of liver-stage parasites known as hypnozoites,…

Populations and Evolution · Quantitative Biology 2021-07-05 Somya Mehra , Eva Stadler , David Khoury , James M. McCaw , Jennifer A. Flegg

Actuating periodically an elastic filament in a viscous liquid generally breaks the constraints of Purcell's scallop theorem, resulting in the generation of a net propulsive force. This observation suggests a method to design simple…

Soft Condensed Matter · Physics 2009-09-29 Eric Lauga