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The gold standard for identifying causal relationships is a randomized controlled experiment. In many applications in the social sciences and medicine, the researcher does not control the assignment mechanism and instead may rely upon…

Applications · Statistics 2016-11-22 Johann Gagnon-Bartsch , Yotam Shem-Tov

We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important application of such tests is the detection of differentially…

Quantitative Methods · Quantitative Biology 2014-05-16 Laurent Jacob , Pierre Neuvial , Sandrine Dudoit

In bioequivalence design, power analyses dictate how much data must be collected to detect the absence of clinically important effects. Power is computed as a tail probability in the sampling distribution of the pertinent test statistics.…

Methodology · Statistics 2025-01-27 Luke Hagar , Nathaniel T. Stevens

Explosive growth in the amount of genomic data is matched by increasing power of consumer-grade computers. Even applications that require powerful servers can be quickly tested on desktop or laptop machines if we can generate representative…

Genomics · Quantitative Biology 2017-11-20 Anthony J. Greenberg

In order to adapt the Wasserstein distance to the large sample multivariate non-parametric two-sample problem, making its application computationally feasible, permutation tests based on the Sinkhorn divergence between probability vectors…

Statistics Theory · Mathematics 2022-09-30 E. del Barrio , J. S. Osorio , A. J. Quiroz

The somatic mutations in the pathways that drive cancer development tend to be mutually exclusive across tumors, providing a signal for distinguishing driver mutations from a larger number of random passenger mutations. This mutual…

Quantitative Methods · Quantitative Biology 2016-07-11 Mark D. M. Leiserson , Matthew A. Reyna , Benjamin J. Raphael

The technique of subsampling has been extensively employed to address the challenges posed by limited computing resources and meet the needs for expedite data analysis. Various subsampling methods have been developed to meet the challenges…

Methodology · Statistics 2024-09-24 Haixiang Zhang , HaiYing Wang

One of the most popular class of tests for independence between two random variables is the general class of rank statistics which are invariant under permutations. This class contains Spearman's coefficient of rank correlation statistic,…

Computation · Statistics 2009-02-04 Ehab F. Abd-Elfattah

When primed with only a handful of training samples, very large, pretrained language models such as GPT-3 have shown competitive results when compared to fully-supervised, fine-tuned, large, pretrained language models. We demonstrate that…

Computation and Language · Computer Science 2022-03-04 Yao Lu , Max Bartolo , Alastair Moore , Sebastian Riedel , Pontus Stenetorp

Quantum tomography is a process of quantum state reconstruction using data from multiple measurements. An essential goal for a quantum tomography algorithm is to find measurements that will maximize the useful information about an unknown…

Quantum Physics · Physics 2020-08-05 A. D. Moiseevskiy , G. I. Struchalin , S. S. Straupe , S. P. Kulik

Clinical machine learning applications are often plagued with confounders that can impact the generalizability and predictive performance of the learners. Confounding is especially problematic in remote digital health studies where the…

Randomized experiments are a crucial tool for causal inference in many different fields. Rerandomization addresses any covariate imbalance in such experiments by resampling treatment assignments until certain balance criteria are satisfied.…

Methodology · Statistics 2025-05-27 Jiuyao Lu , Daogao Liu , Zhanran Lin , Xiaomeng Wang

High-dimensional changepoint inference that adapts to various change patterns has received much attention recently. We propose a simple, fast yet effective approach for adaptive changepoint testing. The key observation is that two…

Methodology · Statistics 2022-05-03 Guanghui Wang , Long Feng

Public data repositories have enabled researchers to compare results across multiple genomic studies in order to replicate findings. A common approach is to first rank genes according to an hypothesis of interest within each study. Then,…

Applications · Statistics 2012-06-29 Loki Natarajan , Minya Pu , Karen Messer

We propose using a permutation test to detect discontinuities in an underlying economic model at a known cutoff point. Relative to the existing literature, we show that this test is well suited for event studies based on time-series data.…

Econometrics · Economics 2022-07-12 Federico A. Bugni , Jia Li , Qiyuan Li

This paper presents a methodology for using varying sample sizes in sequential quadratic programming (SQP) methods for solving equality constrained stochastic optimization problems. The first part of the paper deals with the delicate issue…

Optimization and Control · Mathematics 2023-03-23 Albert S. Berahas , Raghu Bollapragada , Baoyu Zhou

In mutation testing the question whether a mutant is equivalent to its program is important in order to compute the correct mutation score. Unfortunately, answering this question is not always possible and can hardly be obtained just by…

Software Engineering · Computer Science 2012-07-11 Simona Nica , Franz Wotawa

The log-normal distribution is used to describe the positive data, that it has skewed distribution with small mean and large variance. This distribution has application in many sciences for example medicine, economics, biology and…

Methodology · Statistics 2015-08-10 Saba Aghadoust , Kamel Abdollahnezhad , Farhad Yaghmaei , Ali Akbar Jafari

The paper concerns a new statistical method for assessing dissimilarity of two random sets based on one realisation of each of them. The method focuses on shapes of the components of the random sets, namely on the curvature of their…

We describe a very simple method for `consistent sampling' that allows for sampling with replacement. The method extends previous approaches to consistent sampling, which assign a pseudorandom real number to each element, and sample those…

Data Structures and Algorithms · Computer Science 2018-08-31 Ronald L. Rivest