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We develop a formal model of the emergence of self-constructing objects (e.g. heteropolymers with autocatalytic capability) in an open system, which don't contain such objects initially. The objects are constructed from subunits (e.g.…

Statistical Mechanics · Physics 2025-01-06 P. O. Mchedlov-Petrosyan , L. N. Davydov

Motivated by the theory of reaction kinetics based on nonequilibrium thermodynamics and the linear stability of driven reaction-diffusion, we apply the Fokker-Planck equation to describe the population dynamics of an ensemble of reactive…

Chemical Physics · Physics 2019-07-31 Hongbo Zhao , Martin Z. Bazant

Species or population that proliferate faster than others become dominant in numbers. Catalysis allows catalytic sets within a molecular reaction network to dominate the non catalytic parts of the network by processing most of the available…

Cell Behavior · Quantitative Biology 2016-08-31 Rudolf Hanel

Evolution produces complex and structured networks of interacting components in chemical, biological, and social systems. We describe a simple mathematical model for the evolution of an idealized chemical system to study how a network of…

Adaptation and Self-Organizing Systems · Physics 2014-03-05 Sanjay Jain , Sandeep Krishna

Autocatalysis underlies the ability of chemical and biochemical systems to replicate. Recently, Blokhuis et al. gave a stoechiometric definition of autocatalysis for reaction networks, stating the existence of a combination of reactions…

Molecular Networks · Quantitative Biology 2022-01-25 Jeremie Unterberger , Philippe Nghe

Biological responses often obey Weber's law, according to which the magnitude of the response depends only on the fold change in the external input. In this study, we demonstrate that a system involving a simple autocatalytic reaction shows…

Biological Physics · Physics 2015-03-19 Masayo Inoue , Kunihiko Kaneko

A Markov chain model for spatially distributed autocatalytic systems with a quadratic reaction rate is considered. An approximate solution for the local probability distribution is obtained in the form of a perturbation expansion for the…

Statistical Mechanics · Physics 2009-10-31 Mikhail V. Velikanov , Raymond Kapral

We consider a reaction-diffusion system which may serve as a model for a ferment catalytic reaction in chemistry. The model consists of a system of reaction diffusion equations with unbounded time dependent coefficients and different…

Analysis of PDEs · Mathematics 2022-06-14 Mohamed Majdoub , Nasser-eddine Tatar

Developing a mathematical understanding of autocatalysis in reaction networks has both theoretical and practical implications. We review definitions of autocatalytic networks and prove some properties for minimal autocatalytic subnetworks…

Molecular Networks · Quantitative Biology 2023-11-14 Praful Gagrani , Victor Blanco , Eric Smith , David Baum

Universal intermittent dynamics in a random catalytic reaction network, induced by smallness in the molecule number is reported. Stochastic simulations for a random catalytic reaction network subject to a flow of chemicals show that the…

Statistical Mechanics · Physics 2009-02-20 Akinori Awazu , Kunihiko Kaneko

In this thesis we present a mathematical model describing the population dynamics of molecules in an artificial chemistry where large molecules can be produced by successive ligation of pairs of smaller molecules. The chemistry contains a…

Adaptation and Self-Organizing Systems · Physics 2013-04-03 Varun Giri

Autocatalysis underlies the ability of chemical and biochemical systems to replicate. Autocatalysis was recently defined stoichiometrically for reaction networks; five types of minimal autocatalytic networks, termed autocatalytic cores were…

Molecular Networks · Quantitative Biology 2025-07-22 Praneet Nandan , Philippe Nghe , Jeremie Unterberger

Many decision-making algorithms draw inspiration from the inner workings of individual biological systems. However, it remains unclear whether collective behavior among biological species can also lead to solutions for computational tasks.…

Physics and Society · Physics 2024-09-04 Niek Mooij , Ivan Kryven

Explaining the origin of life requires us to explain how self-replication arises. To be specific, how can a self-replicating entity develop spontaneously from a chemical reaction system in which no reaction is self-replicating? Previously…

Adaptation and Self-Organizing Systems · Physics 2020-12-18 Yu Liu , David Sumpter

We consider the population dynamics of a set of species whose network of catalytic interactions is described by a directed graph. The relationship between the attractors of this dynamics and the underlying graph theoretic structures like…

adap-org · Physics 2009-10-30 Sanjay Jain , Sandeep Krishna

Background: A classical problem in metabolic design is to maximize the production of desired compound in a given chemical reaction network by appropriately directing the mass flow through the network. Computationally, this problem is…

Molecular Networks · Quantitative Biology 2011-10-28 Jakob L. Andersen , Christoph Flamm , Daniel Merkle , Peter F. Stadler

We investigate the catalytic reactions model used in cell modeling. The reaction kinetic is defined through the energies of different species of molecules following random independent distribution. The related statistical physics model has…

Other Quantitative Biology · Quantitative Biology 2015-06-12 David B. Saakian , Laurent Schwartz

We investigate joint spectral characteristics of a family of matrices $\mathcal F $, associated with products in the semigroup generated by $\mathcal F$. In the literature, extremal measures such as the well-known joint spectral radius and…

Dynamical Systems · Mathematics 2026-04-27 Francesco Paolo Maiale , Anastasiia Trofimova , Nicola Guglielmi

We analyzed the stochastic behavior of systems controlled by autocatalytic reaction A+X -> X+X. Assuming the distribution of reacting particles in the system volume to be uniform, we introduced the notion of the point model of reaction…

Statistical Mechanics · Physics 2007-05-23 L. Pal

Template directed replication of nucleic acids is at the essence of all living beings and a major milestone for any origin of life scenario. We here present an idealized model of prebiotic sequence replication, where binary polymers act as…

Molecular Networks · Quantitative Biology 2017-12-20 Harold Fellermann , Shinpei Tanaka , Steen Rasmussen