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As an effective method to deliver external materials into biological cells, microinjection has been widely applied in the biomedical field. However, the cognition of cell mechanical property is still inadequate, which greatly limits the…

Robotics · Computer Science 2022-11-29 Shengzheng Kang , Zhicheng Song , Xiaolong Yang , Yao Li , Hongtao Wu , Tao Li

The "equation-free'' approach has been proposed in recent years as a general framework for developing multiscale methods to efficiently capture the macroscale behavior of a system using only the microscale models. In this paper, we take a…

Numerical Analysis · Mathematics 2008-06-11 Weinan E , Eric Vanden-Eijnden

This article presents two model-free controllers for wind-turbine torque and pitch control. These controllers are based on reinforcement learning (RL) and Bayesian optimization (BO) and do not rely on any mathematical model of the…

Fluid Dynamics · Physics 2022-07-14 L. Schena , E. Gillyns , W. Munters , S. Buckingham , M. A. Mendez

Living organisms rely on endogenous feedback mechanisms to maintain homeostasis in the presence of uncertainty and environmental fluctuations. An emerging challenge at the interface of control systems engineering and synthetic biology is…

Systems and Control · Electrical Eng. & Systems 2026-02-24 Mario di Bernardo

Active thermal control is crucial in achieving the required accuracy and throughput in many industrial applications, e.g., in the medical industry, high-power lighting industry, and semiconductor industry. Thermoelectric Modules (TEMs) can…

Systems and Control · Electrical Eng. & Systems 2020-06-19 Enzo Evers , Rens Slenders , Rob van Gils , Tom Oomen

Neuromorphic engineering is a rapidly developing field that aims to take inspiration from the biological organization of neural systems to develop novel technology for computing, sensing, and actuating. The unique properties of such systems…

Systems and Control · Electrical Eng. & Systems 2022-01-26 Luka Ribar , Rodolphe Sepulchre

Model-based Reinforcement Learning (MBRL) allows data-efficient learning which is required in real world applications such as robotics. However, despite the impressive data-efficiency, MBRL does not achieve the final performance of…

Machine Learning · Computer Science 2019-08-19 Zhang-Wei Hong , Joni Pajarinen , Jan Peters

Designing efficient closed-loop control algorithms is a key issue in Additive Manufacturing (AM), as various aspects of the AM process require continuous monitoring and regulation, with temperature being a particularly significant factor.…

Optimization and Control · Mathematics 2023-07-17 Eleni Zavrakli , Andrew Parnell , Andrew Dickson , Subhrakanti Dey

A multiscale mathematical model describing the genesis and ecology of algal-bacterial photogranules and the metals biosorption on their solid matrix within a sequencing batch reactor (SBR) is presented. The granular biofilm is modelled as a…

Cell Behavior · Quantitative Biology 2023-01-31 F. Russo , A. Tenore , M. R. Mattei , L. Frunzo

This paper introduces a continuous model for Multi-cellular Developmental Design. The cells are fixed on a 2D grid and exchange "chemicals" with their neighbors during the growth process. The quantity of chemicals that a cell produces, as…

Artificial Intelligence · Computer Science 2007-05-23 Alexandre Devert , Nicolas Bredèche , Marc Schoenauer

This paper deals with the problem of cost-optimal operation of smart buildings that integrate a centralized HVAC system, photovoltaic generation and both thermal and electrical storage devices. Building participation in a Demand-Response…

Systems and Control · Computer Science 2019-02-19 Gianni Bianchini , Marco Casini , Daniele Pepe , Antonio Vicino , Giovanni Gino Zanvettor

Mathematical models are increasingly a part of microbiological research. Here, we share our perspective on how modeling advances the discipline by: (i) enforcing logical consistency, (ii) enabling quantitative prediction, (iii) extracting…

Other Quantitative Biology · Quantitative Biology 2026-04-22 Jamie A. Lopez , Amir Erez

This article makes discrete masked models for the generative modeling of discrete data controllable. The goal is to generate samples of a discrete random variable that adheres to a posterior distribution, satisfies specific constraints, or…

Machine Learning · Computer Science 2024-10-04 Wei Guo , Yuchen Zhu , Molei Tao , Yongxin Chen

Mathematical and statistical models underlie many of the world's most important fisheries management decisions. Since the 19th century, difficulty calibrating and fitting such models has been used to justify the selection of simple,…

Unlike the case with identical neighboring agents whose actions are mirrored, the problem of distributed formation control design with heterogeneous sensing is not straightforward. In this paper, we consider the problem of distributed…

Systems and Control · Electrical Eng. & Systems 2023-11-22 Jin Chen , Bayu Jayawardhana , Hector Garcia de Marina

Diffuse pollution in rural areas due to agricultural run-off is a widespread and difficult problem to address due to the vast areas affected. Drainage channels do receive these polluted waters, but its introduction in the conventional…

Populations and Evolution · Quantitative Biology 2018-06-27 Maria Jesus Garcia-Galan , Raquel Gutierrez , Enrica Uggetti , Victor Matamoros , Joan Garcia , Ivet Ferrer

Biopharmaceutical manufacturing faces critical challenges, including complexity, high variability, lengthy lead time, and limited historical data and knowledge of the underlying system stochastic process. To address these challenges, we…

Machine Learning · Computer Science 2020-06-18 Hua Zheng , Wei Xie , Mingbin Ben Feng

Battery energy storage is an essential component of a microgrid. The working temperature of the battery is an important factor as a high-temperature condition generally increases losses, reduces useful life, and can even lead to fire…

Systems and Control · Electrical Eng. & Systems 2020-11-24 Anshuman Singh , Wang Peng , Hung D. Nguyen

The global population increase leads to a high food demand, and to reach this target products such as pesticides are needed to protect the crops. Research is focusing on the development of new products that can be less harmful to the…

Quantitative Methods · Quantitative Biology 2025-02-13 Enrico Sangoi , Federica Cattani , Faheem Padia , Federico Galvanin

A novel, model free, approach to experimental closed-loop flow control is implemented on a separated flow. Feedback control laws are generated using genetic programming where they are optimized using replication, mutation and cross-over of…

Fluid Dynamics · Physics 2015-06-19 Nicolas Gautier , Thomas Duriez , Jean-Luc Aider , Bernd Noack , Marc Segond , Markus Abel