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Thin-layer photobioreactors (TLRs) exhibit fast hydrodynamic and thermal dynamics, strong nonlinear photosynthetic responses and significant time-variability due to irradiance fluctuations and biomass growth. These characteristics challenge…

Systems and Control · Electrical Eng. & Systems 2026-05-26 José González-Hernández , Ainoa Morillas-España , José Luis Guzmán , José Carlos Moreno , Alain Vande Wouwer

Optimal experimental design for parameter precision attempts to maximize the information content in experimental data for a most effective identification of parametric model. With the recent developments in miniaturization and…

The potential of industrial applications for microalgae has motivated their recent fast development. Their growth dynamics depends on different factors that must be optimized. Since they get their energy from photosynthesis, light is a key…

Numerical Analysis · Mathematics 2021-08-24 Olivier Bernard , Liu-Di Lu

Biological motor control provides highly effective solutions to difficult control problems in spite of the complexity of the plant and the significant delays in sensory feedback . Such delays are expected to lead to non trivial stability…

Optimization and Control · Mathematics 2009-09-15 Dmitry Volkinshtein , Ron Meir

We are introducing a model-free control and a control with a restricted model for finite-dimensional complex systems. This control design may be viewed as a contribution to "intelligent" PID controllers, the tuning of which becomes quite…

Optimization and Control · Mathematics 2009-04-03 Michel Fliess , Cédric Join

Navigation problems under unknown varying conditions are among the most important and well-studied problems in the control field. Classic model-based adaptive control methods can be applied only when a convenient model of the plant or…

Grid-interactive building control is a challenging and important problem for reducing carbon emissions, increasing energy efficiency, and supporting the electric power grid. Currently researchers and practitioners are confronted with a…

Systems and Control · Electrical Eng. & Systems 2022-10-20 David Biagioni , Xiangyu Zhang , Christiane Adcock , Michael Sinner , Peter Graf , Jennifer King

Microfiltration technology is a widely used engineering strategy for fresh water production and water treatment. The major concern in many applications is the formation of a biological fouling layer leading to increased hydraulic resistance…

Biological Physics · Physics 2021-04-12 V. Luongo , M. R. Mattei , L. Frunzo , B. D'Acunto , K. Gupta , S. Chellam , N. G. Cogan

Energy-based modelling brings engineering insight to the understanding of biomolecular systems. It is shown how well-established control engineering concepts, such as loop-gain, arise from energy feedback loops and are therefore amenable to…

Molecular Networks · Quantitative Biology 2021-03-30 Peter J Gawthrop

This paper proposes an innovative solution to the growing issue of greenhouse gas emissions: a closed photobioreactor (PBR) facade system to mitigate greenhouse gas (GHG) concentrations. With digital fabrication technology, this study…

Computational Engineering, Finance, and Science · Computer Science 2026-04-30 Xiujin Liu

Design of process control scheme is critical for quality assurance to reduce variations in manufacturing systems. Taking semiconductor manufacturing as an example, extensive literature focuses on control optimization based on certain…

Machine Learning · Computer Science 2023-09-19 Yanrong Li , Juan Du , Wei Jiang

The established microalgae growth models are semi-empirical or considerable fitting coefficients exist currently. Therefore, the ability of the model prediction is reduced by the numerous fitting coefficients. Furthermore, the predicted…

Biological Physics · Physics 2022-05-12 C. Y. Ma

It is increasingly common for therapies in oncology to be given in combination. In some cases, patients can benefit from the interaction between two drugs, although often at the risk of higher toxicity. A large number of designs to conduct…

The control and modeling of robot dynamics have increasingly adopted model-free control strategies using machine learning. Given the non-linear elastic nature of bionic robotic systems, learning-based methods provide reliable alternatives…

Robotics · Computer Science 2024-10-08 Po-Yu Hsieh , June-Hao Hou

How morphogenesis depends on cell properties is an active direction of research. Here, we focus on mechanical models of growing plant tissues, where microscopic (sub)cellular structure is taken into account. In order to establish links…

Analysis of PDEs · Mathematics 2023-11-21 Arezki Boudaoud , Annamaria Kiss , Mariya Ptashnyk

Biological systems are governed by coupled interactions between intracellular metabolism and bioreactor operation that span multiple time scales. Constraint-based metabolic models are widely used to describe intracellular metabolism, but…

Quantitative Methods · Quantitative Biology 2026-03-30 Peter E. Carstensen , Teddy Groves , Lars K. Nielsen , Ulrich Krühne , Krist V. Gernaey , John B. Jørgensen

The quantitative description of marine systems is constrained by a major issue of scale separation: most marine biochemical processes occur at sub-centimeter scales, while the contribution to the Earth's biogeochemical cycles is expressed…

Atmospheric and Oceanic Physics · Physics 2019-11-14 Francesco Paparella , Marcello Vichi

We present a novel approach to control design for nonlinear systems which leverages model-free policy optimization techniques to learn a linearizing controller for a physical plant with unknown dynamics. Feedback linearization is a…

Plant factories with artificial light are widely researched for food production in a controlled environment. For such control tasks, models of the energy and resource exchange in the production unit as well as those of the plant's growth…

Systems and Control · Electrical Eng. & Systems 2020-06-15 Murali Padmanabha , Lukas Beckenbach , Stefan Streif

Most microorganisms regulate their cell size. We review here some of the mathematical formulations of the problem of cell size regulation. We focus on coarse-grained stochastic models and the statistics they generate. We review the…

Cell Behavior · Quantitative Biology 2018-01-03 Po-Yi Ho , Jie Lin , Ariel Amir