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Deep neural network (DNN) models have recently obtained state-of-the-art prediction accuracy for the transcription factor binding (TFBS) site classification task. However, it remains unclear how these approaches identify meaningful DNA…

Machine Learning · Computer Science 2016-10-20 Jack Lanchantin , Ritambhara Singh , Beilun Wang , Yanjun Qi

Deep neural networks excel in mapping genomic DNA sequences to associated readouts (e.g., protein-DNA binding). Beyond prediction, the goal of these networks is to reveal to scientists the underlying motifs (and their syntax) which drive…

Genomics · Quantitative Biology 2024-10-10 Alex M. Tseng , Gokcen Eraslan , Tommaso Biancalani , Gabriele Scalia

The graph structure is a commonly used data storage mode, and it turns out that the low-dimensional embedded representation of nodes in the graph is extremely useful in various typical tasks, such as node classification, link prediction ,…

Social and Information Networks · Computer Science 2020-08-03 Xing Li , Wei Wei , Xiangnan Feng , Xue Liu , Zhiming Zheng

Dense regions in networks are an indicator of interesting and unusual information. However, most existing methods only consider simple, undirected, unweighted networks. Complex networks in the real-world often have rich information though:…

Social and Information Networks · Computer Science 2021-03-08 Ahmet Erdem Sariyuce

This work considers the task of representation learning on the attributed relational graph (ARG). Both the nodes and edges in an ARG are associated with attributes/features allowing ARGs to encode rich structural information widely observed…

Machine Learning · Computer Science 2022-08-10 Yifei Wang , Shiyang Chen , Guobin Chen , Ethan Shurberg , Hang Liu , Pengyu Hong

Link prediction plays an important role in network analysis and applications. Recently, approaches for link prediction have evolved from traditional similarity-based algorithms into embedding-based algorithms. However, most existing…

Social and Information Networks · Computer Science 2020-08-11 Lei Wang , Jing Ren , Bo Xu , Jianxin Li , Wei Luo , Feng Xia

This paper introduces a generalization of Convolutional Neural Networks (CNNs) to graphs with irregular linkage structures, especially heterogeneous graphs with typed nodes and schemas. We propose a novel spatial convolution operation to…

Machine Learning · Computer Science 2019-07-23 Aravind Sankar , Xinyang Zhang , Kevin Chen-Chuan Chang

Following the success of deep convolutional networks in various vision and speech related tasks, researchers have started investigating generalizations of the well-known technique for graph-structured data. A recently-proposed method called…

Social and Information Networks · Computer Science 2018-09-21 John Boaz Lee , Ryan A. Rossi , Xiangnan Kong , Sungchul Kim , Eunyee Koh , Anup Rao

A common problem in bioinformatics is related to identifying gene regulatory regions marked by relatively high frequencies of motifs, or deoxyribonucleic acid sequences that often code for transcription and enhancer proteins. Predicting…

Genomics · Quantitative Biology 2021-01-22 Ethan Jacob Moyer , Anup Das

Motivation Protein fold recognition is an important problem in structural bioinformatics. Almost all traditional fold recognition methods use sequence (homology) comparison to indirectly predict the fold of a tar get protein based on the…

Machine Learning · Computer Science 2017-06-06 Jie Hou , Badri Adhikari , Jianlin Cheng

We propose a novel semantic segmentation algorithm by learning a deconvolution network. We learn the network on top of the convolutional layers adopted from VGG 16-layer net. The deconvolution network is composed of deconvolution and…

Computer Vision and Pattern Recognition · Computer Science 2015-05-19 Hyeonwoo Noh , Seunghoon Hong , Bohyung Han

A deep generative model is developed for representation and analysis of images, based on a hierarchical convolutional dictionary-learning framework. Stochastic {\em unpooling} is employed to link consecutive layers in the model, yielding…

Computer Vision and Pattern Recognition · Computer Science 2015-12-25 Yunchen Pu , Xin Yuan , Andrew Stevens , Chunyuan Li , Lawrence Carin

Deep Convolutional Neural Networks (DCNNs) commonly use generic `max-pooling' (MP) layers to extract deformation-invariant features, but we argue in favor of a more refined treatment. First, we introduce epitomic convolution as a building…

Computer Vision and Pattern Recognition · Computer Science 2014-12-02 George Papandreou , Iasonas Kokkinos , Pierre-André Savalle

To mitigate the suboptimal nature of graph structure, Graph Structure Learning (GSL) has emerged as a promising approach to improve graph structure and boost performance in downstream tasks. Despite the proposal of numerous GSL methods, the…

Machine Learning · Computer Science 2024-06-14 Zhiyao Zhou , Sheng Zhou , Bochao Mao , Jiawei Chen , Qingyun Sun , Yan Feng , Chun Chen , Can Wang

In this work, we propose a novel deep network for traffic sign classification that achieves outstanding performance on GTSRB surpassing all previous methods. Our deep network consists of spatial transformer layers and a modified version of…

Computer Vision and Pattern Recognition · Computer Science 2016-07-19 Mrinal Haloi

The inapplicability of amino acid covariation methods to small protein families has limited their use for structural annotation of whole genomes. Recently, deep learning has shown promise in allowing accurate residue-residue contact…

Biomolecules · Quantitative Biology 2019-09-10 Joe G Greener , Shaun M Kandathil , David T Jones

In many applications of computer vision it is important to accurately estimate the trajectory of an object over time by fusing data from a number of sources, of which 2D and 3D imagery is only one. In this paper, we show how to use a deep…

Computer Vision and Pattern Recognition · Computer Science 2021-12-06 Fan Jiang , Andrew Marmon , Ildebrando De Courten , Marc Rasi , Frank Dellaert

Artificial neural networks show promising performance in detecting correlations within data that are associated with specific outcomes. However, the black-box nature of such models can hinder the knowledge advancement in research fields by…

Machine Learning · Computer Science 2023-10-09 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Evolutionary computation methods have been successfully applied to neural networks since two decades ago, while those methods cannot scale well to the modern deep neural networks due to the complicated architectures and large quantities of…

Neural and Evolutionary Computing · Computer Science 2019-03-12 Yanan Sun , Bing Xue , Mengjie Zhang , Gary G. Yen

Transceivers used for telecommunications transmit and receive specific modulation patterns that are represented as sequences of complex numbers. Classifying modulation patterns is challenging because noise and channel impairments affect the…

Machine Learning · Computer Science 2020-10-30 Jakob Krzyston , Rajib Bhattacharjea , Andrew Stark
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