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Growing evidence from recent studies implies that microRNA or miRNA could serve as biomarkers in various complex human diseases. Since wet-lab experiments are expensive and time-consuming, computational techniques for miRNA-disease…

Quantitative Methods · Quantitative Biology 2021-11-30 Thi Ngan Dong , Megha Khosla

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…

Over the years, computer vision researchers have spent an immense amount of effort on designing image features for the visual object recognition task. We propose to incorporate this valuable experience to guide the task of training deep…

Computer Vision and Pattern Recognition · Computer Science 2016-11-15 Ming-Yu Liu , Arun Mallya , Oncel C. Tuzel , Xi Chen

Recently, deep feedforward neural networks have achieved considerable success in modeling biological sensory processing, in terms of reproducing the input-output map of sensory neurons. However, such models raise profound questions about…

Neurons and Cognition · Quantitative Biology 2019-12-16 Hidenori Tanaka , Aran Nayebi , Niru Maheswaranathan , Lane McIntosh , Stephen A. Baccus , Surya Ganguli

Due to the unprecedented success of deep learning, it has become an integral component in several multimedia computing applications in todays world. Unfortunately, deep learning systems are not perfect and can fail, sometimes abruptly,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Varun Totakura , Shayok Chakraborty

We present McGenus, an algorithm to predict RNA secondary structures with pseudoknots. The method is based on a classification of RNA structures according to their topological genus. McGenus can treat sequences of up to 1000 bases and…

Biomolecules · Quantitative Biology 2013-02-18 M. Bon , C. Micheletti , H. Orland

Accelerating Magnetic Resonance Imaging (MRI) reduces scan time but often degrades image quality. While Implicit Neural Representations (INRs) show promise for MRI reconstruction, they struggle at high acceleration factors due to weak prior…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Ziad Al-Haj Hemidi , Eytan Kats , Mattias P. Heinrich

Deep neural networks are powerful tools for solving nonlinear problems in science and engineering, but training highly accurate models becomes challenging as problem complexity increases. Non-convex optimization and sensitivity to…

Machine Learning · Computer Science 2026-04-20 Ethan Mulle , Wei Kang , Qi Gong

A novel group of small non-coding RNA, known as microRNA (miRNA) is predicted to regulate as high as 90% of the coding genes in human. The diversity and abundance of miRNA targets offer an enormous level of combinatorial possibilities and…

Genomics · Quantitative Biology 2010-09-03 Sushmita Mookherjee , Mithun Sinha , Saikat Mukhopadhyay , Nitai P. Bhattacharyya , P. K. Mohanty

Materials discovery is crucial for making scientific advances in many domains. Collections of data from experiments and first-principle computations have spurred interest in applying machine learning methods to create predictive models…

The inner structure of a material is called microstructure. It stores the genesis of a material and determines all its physical and chemical properties. While microstructural characterization is widely spread and well known, the…

Computer Vision and Pattern Recognition · Computer Science 2018-02-16 Seyed Majid Azimi , Dominik Britz , Michael Engstler , Mario Fritz , Frank Mücklich

Ability of deep networks to extract high level features and of recurrent networks to perform time-series inference have been studied. In view of universality of one hidden layer network at approximating functions under weak constraints, the…

Neural and Evolutionary Computing · Computer Science 2014-12-19 Sharat C. Prasad , Piyush Prasad

Deep neural networks (DNNs) have become ubiquitous thanks to their remarkable ability to model complex patterns across various domains such as computer vision, speech recognition, robotics, etc. While large DNN models are often more…

Machine Learning · Computer Science 2025-11-18 Omkar Shende , Gayathri Ananthanarayanan , Marcello Traiola

Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive…

Over the long history of machine learning, which dates back several decades, recurrent neural networks (RNNs) have been used mainly for sequential data and time series and generally with 1D information. Even in some rare studies on 2D…

Computer Vision and Pattern Recognition · Computer Science 2021-03-05 Nguyen Huu Phong , Bernardete Ribeiro

We propose a deep supervised learning algorithm based on low-discrepancy sequences as the training set. By a combination of theoretical arguments and extensive numerical experiments we demonstrate that the proposed algorithm significantly…

Machine Learning · Computer Science 2020-05-27 Siddhartha Mishra , T. Konstantin Rusch

Computational identification of promoters is notoriously difficult as human genes often have unique promoter sequences that provide regulation of transcription and interaction with transcription initiation complex. While there are many…

Genomics · Quantitative Biology 2018-10-04 Ramzan Umarov , Hiroyuki Kuwahara , Yu Li , Xin Gao , Victor Solovyev

Learning effective protein representations is critical in a variety of tasks in biology such as predicting protein function or structure. Existing approaches usually pretrain protein language models on a large number of unlabeled amino acid…

Machine Learning · Computer Science 2023-01-31 Zuobai Zhang , Minghao Xu , Arian Jamasb , Vijil Chenthamarakshan , Aurelie Lozano , Payel Das , Jian Tang

Deep-predictive-coding networks (DPCNs) are hierarchical, generative models. They rely on feed-forward and feed-back connections to modulate latent feature representations of stimuli in a dynamic and context-sensitive manner. A crucial…

Artificial Intelligence · Computer Science 2021-09-27 Isaac J. Sledge , Jose C. Principe

Magnetic resonance imaging (MRI) is a crucial medical imaging modality. However, long acquisition times remain a significant challenge, leading to increased costs, and reduced patient comfort. Recent studies have shown the potential of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Amirmohammad Shamaei , Alexander Stebner , Salome , Bosshart , Johanna Ospel , Gouri Ginde , Mariana Bento , Roberto Souza