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We study the formation of spot patterns seen in a variety of bacterial species when the bacteria are subjected to oxidative stress due to hazardous byproducts of respiration. Our approach consists of coupling the cell density field to a…

We investigate single-cell directional sensing from diffusing chemoattractant signals released by a localized source. We focus on the low-concentration regime in which receptor activity is discrete and cellular decisions are made on…

Cell Behavior · Quantitative Biology 2026-03-12 Vincent Fiorino , Sean D. Lawley , Alan E. Lindsay

Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

Cell Behavior · Quantitative Biology 2015-12-09 Gabriele Micali , Robert G. Endres

During the past century, biologists and mathematicians investigated two mechanisms underlying bacteria motion: the run phase during which bacteria move in straight lines and the tumble phase in which they change their orientation. When…

Analysis of PDEs · Mathematics 2025-05-19 Alain Blaustein

We present a novel approach for the analysis of multivariate case-control georeferenced data using Bayesian inference in the context of disease mapping, where the spatial distribution of different types of cancers is analyzed. Extending…

Microorganisms like bacteria can sense concentration of chemo-attractants in its medium very accurately. They achieve this through interaction between the receptors on their cell surface and the chemo-attractant molecules (like sugar). But…

Soft Condensed Matter · Physics 2015-06-04 Surya K. Ghosh , Tapanendu Kundu , Anirban Sain

Sensory systems have evolved to respond to input stimuli of certain statistical properties, and to reliably transmit this information through biochemical pathways. Hence, for an experimentally well-characterized sensory system, one ought to…

Cell Behavior · Quantitative Biology 2014-10-30 Diana Clausznitzer , Gabriele Micali , Silke Neumann , Victor Sourjik , Robert G. Endres

Ephemeral aggregations of bacteria are ubiquitous in the environment, where they serve as hotbeds of metabolic activity, nutrient cycling, and horizontal gene transfer. In many cases, these regions of high bacterial concentration are…

Bacteria are easily characterizable model organisms with an impressively complicated set of capabilities. Among their capabilities is quorum sensing, a detailed cell-cell signaling system that may have a common origin with eukaryotic…

Neurons and Cognition · Quantitative Biology 2017-09-14 Archana Ram , Andrew Lo

Chemotactic bacteria have been observed to congregate into highly regular patterns. When the bacteria are placed in the center of a dish, a wave of bacteria can travel outward, leaving a regular pattern of spots or stripes in its wake.…

Pattern Formation and Solitons · Physics 2009-09-29 William J. Bruno

Bioconvection is a phenomenon caused by microorganisms with tactic properties. To effectively utilize bioconvection for industrial purposes, it is necessary to find a way to control it. In this study, we performed a three-dimensional…

Fluid Dynamics · Physics 2025-05-14 Hideki Yanaoka , Daichi Koizumi

{\sl Escherichia coli} ({\sl E. coli}) bacteria govern their trajectories by switching between running and tumbling modes as a function of the nutrient concentration they experienced in the past. At short time one observes a drift of the…

Statistical Mechanics · Physics 2011-12-08 Sakuntala Chatterjee , Rava Azeredo da Silveira , Yariv Kafri

Swimming bacteria detect chemical gradients by performing temporal comparisons of recent measurements of chemical concentration. These comparisons are described quantitatively by the chemotactic response function, which we expect to…

Cell Behavior · Quantitative Biology 2009-11-13 Damon A. Clark , Lars C. Grant

We discuss velocity-jump models for chemotaxis of bacteria with an internal state that allows the velocity jump rate to depend on the memory of the chemoattractant concentration along their path of motion. Using probabilistic techniques, we…

Numerical Analysis · Mathematics 2011-11-23 Mathias Rousset , Giovanni Samaey

The induced diffusion of tracers in a bacterial suspension is studied theoretically and experimentally at low bacterial concentrations. Considering the swimmer-tracer hydrodynamic interactions at low-Reynolds number and using a kinetic…

Soft Condensed Matter · Physics 2015-06-11 G. L. Miño , J. Dunstan , A. Rousselet , E. Clement , R. Soto

Bacteria live in environments that are continuously fluctuating and changing. Exploiting any predictability of such fluctuations can lead to an increased fitness. On longer timescales bacteria can "learn" the structure of these fluctuations…

Cell Behavior · Quantitative Biology 2021-01-05 Stefan Landmann , Caroline M. Holmes , Mikhail Tikhonov

Communication and coordination play a major role in the ability of bacterial cells to adapt to ever changing environments and conditions. Recent work has shown that such coordination underlies several aspects of bacterial responses…

Quantitative Methods · Quantitative Biology 2016-04-12 Shashank Singh , Sabrina Rashid , Zhicheng Long , Saket Navlakha , Hanna Salman , Zoltan N. Oltvai , Ziv Bar-Joseph

A discrete chemotactic predator-prey model is proposed in which the prey secrets a diffusing chemical which is sensed by the predator and vice versa. Two dynamical states corresponding to catching and escaping are identified and it is shown…

Populations and Evolution · Quantitative Biology 2015-05-20 Ankush Sengupta , Tobias Kruppa , Hartmut Löwen

Motivated by observations of the dynamics of {\it Myxococcus xanthus}, we present a self-interacting random walk model that describes the competition between chemokinesis and chemotaxis. Cells are constrained to move in one dimension, but…

Statistical Mechanics · Physics 2016-08-31 Maria R. D'Orsogna , Marc Suchard , Tom Chou

Most of our understanding of bacterial chemotaxis comes from studies of Escherichia coli. However, recent evidence suggests significant departures from the E. coli paradigm in other bacterial species. This variation may stem from different…

Cell Behavior · Quantitative Biology 2015-03-27 Martin Godány , Bhavin S. Khatri , Richard A. Goldstein
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