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We study deformability-based sorting of same-size RBCs via DLD using an in-house integral equation solver. Our goal is to quantitatively characterize the physical mechanisms that enable the cell separation. To this end, we systematically…

Computational Physics · Physics 2018-11-30 Gokberk Kabacaoglu , George Biros

Deterministic lateral displacement (DLD) microfluidic devices promise versatile and precise processing of biological samples. However, this prospect has been realized so far only for rigid spherical particles and remains limited for…

Soft Condensed Matter · Physics 2024-06-03 Wei Chien , Zunmin Zhang , Gerhard Gompper , Dmitry A. Fedosov

We introduce LDL, a fast and robust algorithm that localizes a panorama to a 3D map using line segments. LDL focuses on the sparse structural information of lines in the scene, which is robust to illumination changes and can potentially…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Junho Kim , Changwoon Choi , Hojun Jang , Young Min Kim

Inertial lift forces are exploited within inertial microfluidic devices to position, segregate, and sort particles or droplets. However the forces and their focusing positions can currently only be predicted by numerical simulations, making…

Fluid Dynamics · Physics 2016-07-21 Kaitlyn Hood , Sungyon Lee , Marcus Roper

Collisionless suspensions of inertial particles (finite-size impurities) are studied in 2D and 3D spatially smooth flows. Tools borrowed from the study of random dynamical systems are used to identify and to characterise in full generality…

Chaotic Dynamics · Physics 2007-05-23 Jeremie Bec

We numerically examine the driven transport of an overdamped self-propelled particle through a two-dimensional array of circular obstacles. A detailed analysis of transport quantifiers (mobility and diffusivity) has been performed for two…

Soft Condensed Matter · Physics 2023-10-16 Shubhadip Nayak , Sohom Das , Poulami Bag , Tanwi Debnath , Pulak K. Ghosh

We uncover anisotropic permeability in microfluidic deterministic lateral displacement (DLD) arrays. A DLD array can achieve high-resolution bimodal size-based separation of microparticles, including bioparticles, such as cells. For an…

Fluid Dynamics · Physics 2017-09-27 Rohan Vernekar , Timm Krüger , Kevin Loutherback , Keith Morton , David Inglis

Particle Flow Filters perform the measurement update by moving particles to a different location rather than modifying the particles' weight based on the likelihood. Their movement (flow) is dictated by a drift term, which continuously…

Computational Engineering, Finance, and Science · Computer Science 2025-07-04 Simone Servadio

A colloidal particle driven by externally actuated rotation can self-propel parallel to a rigid boundary by exploiting the hydrodynamic coupling that surfaces induce between translation and rotation. As such a roller moves along the…

Fluid Dynamics · Physics 2020-02-20 Alexander Chamolly , Eric Lauga , Soichiro Tottori

We present initial attempts to include the multi-dimensional nature of radiation transport in hydrodynamical simulations of the small-scale structure that arises from the line-driven instability in hot-star winds. Compared to previous 1D or…

Astrophysics · Physics 2009-11-10 Luc Dessart , S. P. Owocki

We prove the dynamical large deviations for a particle system in which particles may have different velocities. We assume that we have two infinite reservoirs of particles at the boundary: this is the so-called boundary driven process. The…

Probability · Mathematics 2010-06-02 Jonathan Farfan , Alexandre B. Simas , Fabio J. Valentim

In this paper, we describe the unification and extension of multiple kinematic theories on the advection of colloidal particles through periodic obstacle lattices of arbitrary geometry and infinitesimally small obstacle size. We focus…

Computational Physics · Physics 2020-03-25 Arnaldo Rodriguez-Gonzalez , Jason P. Gleghorn , Brian J. Kirby

The transport of deformable particles through porous media underlies a wealth of applications ranging from filtration to oil recovery to the transport and spreading of biological agents. Using direct numerical simulations, we analyze the…

Soft Condensed Matter · Physics 2020-06-09 Brato Chakrabarti , Charles Gaillard , David Saintillan

In this paper, we perform molecular dynamics (MD) simulations to study the two-dimensional packing process of both monosized and random size particles with radii ranging from $1.0 \, \mu m$ to $7.0 \, \mu m$. The system was allowed to…

Soft Condensed Matter · Physics 2017-12-01 Carlos Handrey Araujo Ferraz , Samuel Apolinário Marques

A flowing pair of particles in inertial microfluidics gives important insights into understanding and controlling the collective dynamics of particles like cells or droplets in microfluidic devices. They are applied in medical cell analysis…

Fluid Dynamics · Physics 2018-05-25 Christian Schaaf , Felix Rühle , Holger Stark

We provide a generic scheme to separate the particles of a mixture by their physical properties like mass, friction or size. The scheme employs a periodically shaken two dimensional dissipative lattice and hinges on a simultaneous transport…

Chaotic Dynamics · Physics 2018-05-30 Aritra K. Mukhopadhyay , Benno Liebchen , Peter Schmelcher

We solve a design optimization problem for deterministic lateral displacement (DLD) device to sort same-size biological cells by their deformability, in particular to sort red blood cells (RBCs) by their viscosity contrast between the fluid…

Computational Physics · Physics 2019-01-14 Gokberk Kabacaoglu , George Biros

In the fluid transport of particles, it is generally expected that heavy particles carried by a laminar fluid flow moving downward will also move downward. We establish a theory to show, however, that particles can be dynamically levitated…

Fluid Dynamics · Physics 2017-03-20 Jean-Regis Angilella , Daniel J. Case , Adilson E. Motter

In the classical one-dimensional solution of fluid dynamics equations all unknown functions depend only on time t and Cartesian coordinate x. Although fluid spreads in all directions (velocity vector has three components) the whole picture…

Fluid Dynamics · Physics 2010-08-05 Sergey V. Golovin

The transport behavior of a system of gravitationally driven colloidal particles is investigated. The particle interactions are determined by the superparamagnetic behavior of the particles. They can thus be arranged in a crystalline order…

Soft Condensed Matter · Physics 2009-11-11 M. Köppl , P. Henseler , A. Erbe , P. Nielaba , P. Leiderer