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Biophysical modelling of diffusion MRI is necessary to provide specific microstructural tissue properties. However, estimating model parameters from data with limited diffusion gradient strength, such as clinical scanners, has proven…

Medical Physics · Physics 2019-03-21 Sune Nørhøj Jespersen , Jonas Lynge Olesen , Brian Hansen , Noam Shemesh

Magnetic resonance imaging (MRI) is a potent diagnostic tool, but suffers from long examination times. To accelerate the process, modern MRI machines typically utilize multiple coils that acquire sub-sampled data in parallel. Data-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Moritz Erlacher , Martin Zach

Diffusion tensor imaging provides important information on tissue structure and orientation of fiber tracts in brain white matter in vivo. It results in diffusion tensors, which are $3\times3$ symmetric positive definite (SPD) matrices,…

Applications · Statistics 2013-04-17 Ying Yuan , Hongtu Zhu , Martin Styner , John H. Gilmore , J. S. Marron

Brain network analysis plays a crucial role in diagnosing and monitoring neurodegenerative disorders such as Alzheimer's disease (AD). Existing approaches for constructing structural brain networks from diffusion tensor imaging (DTI) often…

Neurons and Cognition · Quantitative Biology 2025-05-30 Xuhang Chen , Michael Kwok-Po Ng , Kim-Fung Tsang , Chi-Man Pun , Shuqiang Wang

Imaging findings inconsistent with those expected at specific chronological age ranges may serve as early indicators of neurological disorders and increased mortality risk. Estimation of chronological age, and deviations from expected…

White matter (WM) tract segmentation is a crucial step for brain connectivity studies. It is performed on diffusion magnetic resonance imaging (dMRI), and deep neural networks (DNNs) have achieved promising segmentation accuracy. Existing…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Wan Liu , Chuyang Ye

Magnetic Resonance Imaging (MRI), including diffusion MRI (dMRI), serves as a ``microscope'' for anatomical structures and routinely mitigates the influence of low signal-to-noise ratio scans by compromising temporal or spatial resolution.…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Chenxu Wu , Qingpeng Kong , Zihang Jiang , S. Kevin Zhou

In utero diffusion MRI provides unique opportunities to non-invasively study the microstructure of tissue during fetal development. A wide range of developmental processes, such as the growth of white matter tracts in the brain, the…

This paper demonstrates spherical convolutional neural networks (S-CNN) offer distinct advantages over conventional fully-connected networks (FCN) at estimating scalar parameters of tissue microstructure from diffusion MRI (dMRI). Such…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Tobias Goodwin-Allcock , Jason McEwen , Robert Gray , Parashkev Nachev , Hui Zhang

While diffusion MRI has been extremely promising in the study of MTBI, identifying patients with recent MTBI remains a challenge. The literature is mixed with regard to localizing injury in these patients, however, gray matter such as the…

Computer Vision and Pattern Recognition · Computer Science 2017-08-31 Shervin Minaee , Yao Wang , Sohae Chung , Xiuyuan Wang , Els Fieremans , Steven Flanagan , Joseph Rath , Yvonne W. Lui

Diffusion MRI affords valuable insights into white matter microstructures, but suffers from low signal-to-noise ratio (SNR), especially at high diffusion weighting (i.e., b-value). To avoid time-intensive repeated acquisition,…

Medical Physics · Physics 2018-07-26 Geng Chen , Yafeng Wu , Dinggang Shen , Pew-Thian Yap

We show that high quality, diverse and realistic-looking diffusion-weighted magnetic resonance images can be synthesized using deep generative models. Based on professional neuroradiologists' evaluations and diverse metrics with respect to…

Computer Vision and Pattern Recognition · Computer Science 2020-06-26 Alejandro Ungría Hirte , Moritz Platscher , Thomas Joyce , Jeremy J. Heit , Eric Tranvinh , Christian Federau

Diffusion weighted MRI (dMRI) provides a non invasive virtual reconstruction of the brain's white matter structures through tractography. Analyzing dMRI measures along the trajectory of white matter bundles can provide a more specific…

Quantitative Methods · Quantitative Biology 2019-06-21 Samuel St-Jean , Maxime Chamberland , Max A. Viergever , Alexander Leemans

White matter hyperintensities (WMH) are commonly found in the brains of healthy elderly individuals and have been associated with various neurological and geriatric disorders. In this paper, we present a study using deep fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-09-20 Hongwei Li , Gongfa Jiang , Jianguo Zhang , Ruixuan Wang , Zhaolei Wang , Wei-Shi Zheng , Bjoern Menze

Ultra-low-field (ULF) MRI is emerging as an alternative modality to high-field (HF) MRI due to its lower cost, minimal siting requirements, portability, and enhanced accessibility factors that enable large-scale deployment. Although ULF-MRI…

This paper is a contribution to the "BraTS 2023 Local Synthesis of Healthy Brain Tissue via Inpainting Challenge". The task of this challenge is to transform tumor tissue into healthy tissue in brain magnetic resonance (MR) images. This…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Alicia Durrer , Philippe C. Cattin , Julia Wolleb

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Accurate detection and segmentation of brain tumors from magnetic resonance imaging (MRI) are essential for diagnosis, treatment planning, and clinical monitoring. While convolutional architectures such as U-Net have long been the backbone…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Arman Behnam

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

Applications · Statistics 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan