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Analyses of targeted genomic sequencing data from next-generation-sequencing (NGS) technologies typically involves mapping reads to a reference sequence or clustering reads. For a number of species a reference genome is not available so the…

Genomics · Quantitative Biology 2016-02-16 Raunaq Malhotra , Daniel Elleder , Le Bao , David R Hunter , Raj Acharya , Mary Poss

This study addresses the issue of predicting the glaucomatous visual field loss from patient disease datasets. Our goal is to accurately predict the progress of the disease in individual patients. As very few measurements are available for…

Machine Learning · Statistics 2016-03-24 Motohide Higaki , Kai Morino , Hiroshi Murata , Ryo Asaoka , Kenji Yamanishi

Spectral clustering is a celebrated algorithm that partitions objects based on pairwise similarity information. While this approach has been successfully applied to a variety of domains, it comes with limitations. The reason is that there…

Statistics Theory · Mathematics 2018-05-24 Kwangjun Ahn , Kangwook Lee , Changho Suh

There has been a continuing demand for traditional and complementary medicine worldwide. A fundamental and important topic in Traditional Chinese Medicine (TCM) is to optimize the prescription and to detect herb regularities from TCM data.…

Quantitative Methods · Quantitative Biology 2020-11-24 Chunyang Ruan , Ye Wang , Yanchun Zhang , Jiangang Ma , Huijuan Chen , Uwe Aickelin , Shanfeng Zhu , Ting Zhang

Genome wide comparisons between enteric bacteria yield large sets of conserved putative regulatory sites on a gene by gene basis that need to be clustered into regulons. Using the assumption that regulatory sites can be represented as…

Biological Physics · Physics 2009-11-07 Erik van Nimwegen , Mihaela Zavolan , Nikolaus Rajewsky , Eric D. Siggia

Clustering attempts to partition data instances into several distinctive groups, while the similarities among data belonging to the common partition can be principally reserved. Furthermore, incomplete data frequently occurs in many…

Machine Learning · Computer Science 2022-08-30 Miao Cheng , Xinge You

The field of deep clustering combines deep learning and clustering to learn representations that improve both the learned representation and the performance of the considered clustering method. Most existing deep clustering methods are…

Machine Learning · Computer Science 2023-02-22 Lukas Miklautz , Martin Teuffenbach , Pascal Weber , Rona Perjuci , Walid Durani , Christian Böhm , Claudia Plant

This paper presents a novel clustering algorithm from the SPINEX (Similarity-based Predictions with Explainable Neighbors Exploration) algorithmic family. The newly proposed clustering variant leverages the concept of similarity and…

Machine Learning · Computer Science 2024-07-11 MZ Naser , Ahmed Naser

The domain of explainable AI is of interest in all Machine Learning fields, and it is all the more important in clustering, an unsupervised task whose result must be validated by a domain expert. We aim at finding a clustering that has high…

Artificial Intelligence · Computer Science 2024-03-28 Mathieu Guilbert , Christel Vrain , Thi-Bich-Hanh Dao

When solving real-world problems, practitioners often hesitate to implement solutions obtained from mathematical models, especially for important decisions. This hesitation stems from practitioners' lack of trust in optimization models and…

Optimization and Control · Mathematics 2025-07-01 Susumu Hashimoto , Takeaki Uno

Hierarchical clustering of networks consists in finding a tree of communities, such that lower levels of the hierarchy reveal finer-grained community structures. There are two main classes of algorithms tackling this problem. Divisive…

Social and Information Networks · Computer Science 2025-11-25 Maximilien Dreveton , Daichi Kuroda , Matthias Grossglauser , Patrick Thiran

We propose a new anytime hierarchical clustering method that iteratively transforms an arbitrary initial hierarchy on the configuration of measurements along a sequence of trees we prove for a fixed data set must terminate in a chain of…

Machine Learning · Statistics 2014-04-15 Omur Arslan , Daniel E. Koditschek

We propose a nearest neighbor based clustering algorithm that results in a naturally defined hierarchy of clusters. In contrast to the agglomerative and divisive hierarchical clustering algorithms, our approach is not dependent on the…

Data Structures and Algorithms · Computer Science 2022-03-16 Kaan Gokcesu , Hakan Gokcesu

This paper studies the hierarchical clustering problem, where the goal is to produce a dendrogram that represents clusters at varying scales of a data set. We propose the ParChain framework for designing parallel hierarchical agglomerative…

Data Structures and Algorithms · Computer Science 2022-02-15 Shangdi Yu , Yiqiu Wang , Yan Gu , Laxman Dhulipala , Julian Shun

This paper presents algorithms for hierarchical, agglomerative clustering which perform most efficiently in the general-purpose setup that is given in modern standard software. Requirements are: (1) the input data is given by pairwise…

Machine Learning · Statistics 2011-09-13 Daniel Müllner

Categorical data clustering (CDC) and link clustering (LC) have been considered as separate research and application areas. The main focus of this paper is to investigate the commonalities between these two problems and the uses of these…

Digital Libraries · Computer Science 2007-05-23 Zengyou He , Xiaofei Xu , Shengchun Deng

We propose an algorithm, HPREF (Hierarchical Partitioning by Repeated Features), that produces a hierarchical partition of a set of clusterings of a fixed dataset, such as sets of clusterings produced by running a clustering algorithm with…

Machine Learning · Statistics 2019-10-01 Alexander Rolle , Luis Scoccola

In unsupervised feature learning, sample specificity based methods ignore the inter-class information, which deteriorates the discriminative capability of representation models. Clustering based methods are error-prone to explore the…

Computer Vision and Pattern Recognition · Computer Science 2020-07-16 Yifei Zhang , Chang Liu , Yu Zhou , Wei Wang , Weiping Wang , Qixiang Ye

A network has a non-overlapping community structure if the nodes of the network can be partitioned into disjoint sets such that each node in a set is densely connected to other nodes inside the set and sparsely connected to the nodes out-…

Social and Information Networks · Computer Science 2016-07-19 Talasila Sai Deepak , Hindol Adhya , Shyamal Kejriwal , Bhanuteja Gullapalli , Saswata Shannigrahi

Many community detection algorithms are inherently stochastic, leading to variations in their output depending on input parameters and random seeds. This variability makes the results of a single run of these algorithms less reliable.…

Social and Information Networks · Computer Science 2025-02-25 Yasamin Tabatabaee , Eleanor Wedell , Minhyuk Park , Tandy Warnow