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Intensive Care Unit (ICU) mortality prediction, which estimates a patient's mortality status at discharge using EHRs collected early in an ICU admission, is vital in critical care. For this task, predictive accuracy alone is insufficient;…

Machine Learning · Computer Science 2025-10-15 Qingwen Li , Xiaohang Zhao , Xiao Han , Hailiang Huang , Lanjuan Liu

Heart attack remain one of the greatest contributors to mortality in the United States and globally. Patients admitted to the intensive care unit (ICU) with diagnosed heart attack (myocardial infarction or MI) are at higher risk of death.…

Machine Learning · Computer Science 2023-05-11 Munib Mesinovic , Peter Watkinson , Tingting Zhu

Data quality on categorical attribute is a difficult problem that has not received as much attention as numerical counterpart. Our basic idea is to employ association rule for the purpose of data quality measurement. Strong rule generation…

Databases · Computer Science 2012-02-16 J. Malar Vizhi , T. Bhuvaneswari

Acute infection, if not rapidly and accurately detected, can lead to sepsis, organ failure and even death. Current detection of acute infection as well as assessment of a patient's severity of illness are imperfect. Characterization of a…

Machine Learning · Computer Science 2020-10-14 Michael B. Mayhew , Elizabeth Tran , Kirindi Choi , Uros Midic , Roland Luethy , Nandita Damaraju , Ljubomir Buturovic

Cardiovascular diseases and heart failures in particular are the main cause of non-communicable disease mortality in the world. Constant patient monitoring enables better medical treatment as it allows practitioners to react on time and…

Artificial Intelligence · Computer Science 2021-04-21 Kordian Gontarska , Weronika Wrazen , Jossekin Beilharz , Robert Schmid , Lauritz Thamsen , Andreas Polze

Aplastic anemia is a rare, life-threatening hematologic disorder characterized by pancytopenia and bone marrow failure. ICU admission in these patients often signals critical complications or disease progression, making early risk…

Machine Learning · Computer Science 2025-05-27 Junyi Fan , Shuheng Chen , Li Sun , Yong Si , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Background: AI-driven prediction algorithms have the potential to enhance emergency medicine by enabling rapid and accurate decision-making regarding patient status and potential deterioration. However, the integration of multimodal data,…

Machine Learning · Computer Science 2025-05-02 Juan Miguel Lopez Alcaraz , Hjalmar Bouma , Nils Strodthoff

Antimicrobial stewardship (AMS) is critical in pediatric intensive care units (PICUs), where diagnostic uncertainty often drives broad-spectrum antibiotic use, increasing antimicrobial resistance and potential long-term harms. Machine…

Machine Learning · Computer Science 2026-05-22 Niklas Raehse , Luregn J. Schlapbach , Daphné Chopard

The area under the receiver operating characteristic curve (AUC) is often used to evaluate the performance of clinical prediction models. Recently, a more refined strategy has been proposed to examine a partial area under the curve (pAUC),…

Applications · Statistics 2016-06-22 Travis Gerke , Svitlana Tyekucheva , Lorelei Mucci , Giovanni Parmigiani

Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the…

Machine Learning · Computer Science 2019-02-14 Benjamin Shickel , Tyler J. Loftus , Lasith Adhikari , Tezcan Ozrazgat-Baslanti , Azra Bihorac , Parisa Rashidi

Causal inference methods are widely applied in various decision-making domains such as precision medicine, optimal policy and economics. Central to these applications is the treatment effect estimation of intervention strategies. Current…

Artificial Intelligence · Computer Science 2021-05-28 Tri Dung Duong , Qian Li , Guandong Xu

There is considerable interest in the use of genetic algorithms to solve problems arising in the areas of scheduling and timetabling. However, the classical genetic algorithm paradigm is not well equipped to handle the conflict between…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Kathryn Dowsland

We develop a flexible Gaussian Process (GP) framework for learning the covariance structure of Age- and Year-specific mortality surfaces. Utilizing the additive and multiplicative structure of GP kernels, we design a genetic programming…

Machine Learning · Statistics 2024-11-20 Mike Ludkovski , Jimmy Risk

In genetic studies of complex diseases, the underlying mode of inheritance is often not known. Thus, the most powerful test or other optimal procedure for one model, e.g. recessive, may be quite inefficient if another model, e.g. dominant,…

Statistics Theory · Mathematics 2007-06-13 Gang Zheng , Boris Freidlin , Joseph L. Gastwirth

We report the development and validation of a data-driven real-time risk score that provides timely assessments for the clinical acuity of ward patients based on their temporal lab tests and vital signs, which allows for timely intensive…

Machine Learning · Computer Science 2017-05-23 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

Accurate patient mortality prediction enables effective risk stratification, leading to personalized treatment plans and improved patient outcomes. However, predicting mortality in healthcare remains a significant challenge, with existing…

Machine Learning · Computer Science 2025-03-28 HyeYoung Lee , Pavel Tsoi

We develop a Gaussian process ("GP") framework for modeling mortality rates and mortality improvement factors. GP regression is a nonparametric, data-driven approach for determining the spatial dependence in mortality rates and jointly…

Methodology · Statistics 2018-04-13 Mike Ludkovski , Jimmy Risk , Howard Zail

Monitoring patients in ICU is a challenging and high-cost task. Hence, predicting the condition of patients during their ICU stay can help provide better acute care and plan the hospital's resources. There has been continuous progress in…

Computation and Language · Computer Science 2020-01-03 Swaraj Khadanga , Karan Aggarwal , Shafiq Joty , Jaideep Srivastava

Heart failure affects millions of people worldwide, significantly reducing quality of life and leading to high mortality rates. Despite extensive research, the relationship between heart failure and mortality rates among ICU patients is not…

Machine Learning · Computer Science 2024-09-04 Negin Ashrafi , Armin Abdollahi , Jiahong Zhang , Maryam Pishgar

Background. Pre-operative risk assessments used in clinical practice are limited in their ability to identify risk for post-operative mortality. We hypothesize that electrocardiograms contain hidden risk markers that can help prognosticate…