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Accurate design of labelled oligo probes for the detection of miRNA biomarkers by Surface Enhanced Raman Scattering (SERS) may improve the exploitation of the plasmonic enhancement. This work, thus, critically investigates the role of probe…

Trisoctahedral (TOH) shaped Au nanocrystals (NCs) have emerged as a new class of metal nanoparticles (MNP) due to its superior catalystic and SERS activities caused by the presence of high density atomic steps and dangling bonds on their…

Materials Science · Physics 2017-05-15 Achyut Maity , Arpan Maiti , Biswarup Satpati , Avinash Patsha , Sandip Dhara , Tapas Kumar Chini

This paper aims to study the reflection characteristics of optical beams in a hybrid graphene-hexagonal Boron Nitride (hBN)-graphene structure, which has been located on SiO2-Si layers. An analytical model is presented to derive the…

We report on a controlled method to fabricate in-situ a superconducting (SC) nanostructure at the apex of the standard W tip of a Scanning Tunnelling Microscope (STM) by pulsing the tunnelling voltage on a graphene covered metal surface. We…

Raman scattering signal can be enhanced through localization of incident field into sub-wavelength hot-spots through plasmonic nano-structures (Surface-enhanced Raman scattering-SERS). Recently, further enhancement of SERS signal via…

The principle and experimental realization of a novel Raman spectroscopic technique entitled stimulated Raman phase shift (SRPS) spectroscopy was demonstrated. This technique depends on the measurement of the stimulated Raman scattering…

Optics · Physics 2024-03-07 Meng Qi , Wenrong Wang , Yuan-ji Li , Jin-xia Feng , Kuan-shou Zhang

Event cameras provide superior temporal resolution, dynamic range, power efficiency, and pixel bandwidth. Spiking Neural Networks (SNNs) naturally complement event data through discrete spike signals, making them ideal for event-based…

Nanofibers functionalized by metal nanostructures and particles are exploited as effective flexible substrates for SERS analysis. Their complex three-dimensional structure may provide Raman signals enhanced by orders of magnitude compared…

Materials Science · Physics 2016-03-16 A. Camposeo , D. Spadaro , D. Magrì , M. Moffa , P. G. Gucciardi , L. Persano , O. M. Maragò , D. Pisignano

We propose a DNA sequencing scheme based on silicene nanopores. Using first principles theory, we compute the electrical properties of such pores in the absence and presence of nucleobases. Within a two-terminal geometry, we analyze the…

Quantitative Methods · Quantitative Biology 2014-05-16 Hatef Sadeghi , S. Bailey , Colin J. Lambert

We introduce a machine learning approach to determine the transition dynamics of silicon atoms on a single layer of carbon atoms, when stimulated by the electron beam of a scanning transmission electron microscope (STEM). Our method is…

Photo-Induced Enhanced Raman Spectroscopy (PIERS) is a new surface enhanced Raman spectroscopy (SERS) modality with an order-of-magnitude Raman signal enhancement of adsorbed analytes over that of typical SERS substrates. Despite the…

Materials Science · Physics 2021-06-01 Junzhi Ye , Rakesh Arul , Michel K. Nieuwoudt , Junzhe Dong , Wei Gao , M. Cather Simpson

Raman spectroscopy can be used to identify molecules such as DNA by the characteristic scattering of light from a laser. It is sensitive at very low concentrations and can accurately quantify the amount of a given molecule in a sample. The…

Applications · Statistics 2026-02-03 Matthew Moores , Kirsten Gracie , Jake Carson , Karen Faulds , Duncan Graham , Mark Girolami

We study theoretically the feasibility of using transverse electronic transport within a nanopore for rapid DNA sequencing. Specifically, we examine the effects of the environment and detection probes on the distinguishability of the DNA…

Soft Condensed Matter · Physics 2009-11-13 Johan Lagerqvist , Michael Zwolak , Massimiliano Di Ventra

Surface enhanced Raman scattering (SERS) in nanoscale hotspots has been placed great hopes upon for identification of minimum chemical traces and in-situ investigation of single molecule structures and dynamics. However, previous work…

Optics · Physics 2016-09-19 Jing Long , Hui Yi , Hongquan Li , Tian Yang

Quantifying formidable multiple coupling effects involved in Surface-enhanced Raman scattering (SERS) is a prerequisite for accurate design of SERS probes with superior detection limit and uniformity which are the targets for trace…

We present a novel approach to achieve hyper spectral resolution, high sensitive detection, and high speed data acquisition Stimulated Raman Spectroscopy by employing amplified offset-phase controlled fs-pulse bursts. In this approach, the…

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling high resolution gene expression profiling within tissues. However, the high cost and scarcity of high resolution ST data remain significant challenges. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

DNA strand displacement (SD) reactions are central to the operation of many synthetic nucleic acid systems, including molecular circuits, sensors, and machines. Over the years, a broad set of design frameworks has emerged to accommodate…

Biomolecules · Quantitative Biology 2025-10-13 Križan Jurinović , Merry Mitra , Rakesh Mukherjee , Thomas E. Ouldridge

A field effect transistor (FET) measurement of a SWNT shows a transition from a metallic one to a p-type semiconductor after helical wrapping of DNA. Water is found to be critical to activate this metal-semiconductor transition in the…

Mesoscale and Nanoscale Physics · Physics 2015-03-17 Misun Cha , Seungwon Jung , Moon-Hyun Cha , Gunn Kim , Jisoon Ihm , Junghoon Lee

We use surface enhanced Raman spectroscopy (SERS) in studying functionalized Au nanoparticles (AuNPs) when incorporated in active-carbon (A-C) based super-capacitor cells. We observe a resonance-like enhancement in the graphitic line…

Mesoscale and Nanoscale Physics · Physics 2023-09-18 H. Grebel , Y. Zhang