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We address the problem of counting the number of strings in a collection where a given pattern appears, which has applications in information retrieval and data mining. Existing solutions are in a theoretical stage. We implement these…

Data Structures and Algorithms · Computer Science 2015-10-02 Travis Gagie , Aleksi Hartikainen , Juha Kärkkäinen , Gonzalo Navarro , Simon J. Puglisi , Jouni Sirén

At the present scenario of the internet, there exist many optimization techniques to improve the Web speed but almost expensive in terms of bandwidth. So after a long investigation on different techniques to compress the data without any…

Information Theory · Computer Science 2014-05-20 Hemant Kumar Saini , Satpal Singh Kushwaha , C. Rama Krishna

Composite endpoints are frequently used as primary or secondary analyses in cardiovascular clinical trials to increase clinical relevance and statistical efficiency. Alternatively, the Win Ratio (WR) and other Win Statistics (WS) analyses…

Methodology · Statistics 2025-12-23 Yunhan Mou , Scott Hummel , Yuan Huang

Large language models (LLMs) and classical machine learning methods offer complementary strengths for predictive modeling, yet their fundamentally different representations and training paradigms hinder effective integration: LLMs rely on…

Computation and Language · Computer Science 2026-04-21 Yunshuo Tian , Akayou Kitessa , Tanuja Chitnis , Yijun Zhao

While short read aligners, which predominantly use the FM-index, are able to easily index one or a few human genomes, they do not scale well to indexing databases containing thousands of genomes. To understand why, it helps to examine the…

Data Structures and Algorithms · Computer Science 2018-11-19 Alan Kuhnle , Taher Mun , Christina Boucher , Travis Gagie , Ben Langmead , Giovanni Manzini

Synthetic data rephrasing has emerged as a powerful technique for enhancing knowledge acquisition during large language model (LLM) pretraining. However, existing approaches operate at the single-document level, rewriting individual web…

Computation and Language · Computer Science 2026-04-10 Jiang Zhou , Yunhao Wang , Xing Wu , Tinghao Yu , Feng Zhang

Reinforcement learning with verifiable rewards (RLVR) has proven effective in eliciting complex reasoning in large language models (LLMs). However, standard RLVR training often leads to excessively verbose processes (in reasoning tasks) and…

Artificial Intelligence · Computer Science 2025-10-01 Gang Li , Yulei Qin , Xiaoyu Tan , Dingkang Yang , Yuchen Shi , Zihan Xu , Xiang Li , Xing Sun , Ke Li

The Block Tree (BT) is a novel compact data structure designed to compress sequence collections. It obtains compression ratios close to Lempel-Ziv and supports efficient direct access to any substring. The BT divides the text recursively…

Data Structures and Algorithms · Computer Science 2018-03-06 Nieves R. Brisaboa , Travis Gagie , Adrián Gómez-Brandón , Gonzalo Navarro

High-throughput DNA sequencers are becoming indispensable in our understanding of diseases at molecular level, in marker-assisted selection in agriculture and in microbial genetics research. These sequencing instruments produce enormous…

Genomics · Quantitative Biology 2014-02-05 Saurabh Gupta , Sanjoy Chaudhury 'and' Binay Panda

Analysis of large-scale sequential data has been one of the most crucial tasks in areas such as bioinformatics, text, and audio mining. Existing string kernels, however, either (i) rely on local features of short substructures in the…

Machine Learning · Computer Science 2019-12-02 Lingfei Wu , Ian En-Hsu Yen , Siyu Huo , Liang Zhao , Kun Xu , Liang Ma , Shouling Ji , Charu Aggarwal

Retrieval-augmented language models can better adapt to changes in world state and incorporate long-tail knowledge. However, most existing methods retrieve only short contiguous chunks from a retrieval corpus, limiting holistic…

Computation and Language · Computer Science 2024-02-01 Parth Sarthi , Salman Abdullah , Aditi Tuli , Shubh Khanna , Anna Goldie , Christopher D. Manning

Motivated by DNA storage in living organisms, and by known biological mutation processes, we study the reverse-complement string-duplication system. We fully classify the conditions under which the system has full expressiveness, for all…

Information Theory · Computer Science 2021-12-23 Eyar Ben-Tolila , Moshe Schwartz

When building Burrows-Wheeler Transforms (BWTs) of truly huge datasets, prefix-free parsing (PFP) can use an unreasonable amount of memory. In this paper we show how if a dataset can be broken down into small datasets that are not very…

Data Structures and Algorithms · Computer Science 2025-06-09 Diego Diaz-Dominguez , Travis Gagie , Veronica Guerrini , Ben Langmead , Zsuzsanna Liptak , Giovanni Manzini , Francesco Masillo , Vikram Shivakumar

In a \emph{weighted sequence}, for every position of the sequence and every letter of the alphabet a probability of occurrence of this letter at this position is specified. Weighted sequences are commonly used to represent imprecise or…

Data Structures and Algorithms · Computer Science 2017-08-28 Carl Barton , Tomasz Kociumaka , Chang Liu , Solon P. Pissis , Jakub Radoszewski

Cartesian tree matching is a form of generalized pattern matching where a substring of the text matches with the pattern if they share the same Cartesian tree. This form of matching finds application for time series of stock prices and can…

Data Structures and Algorithms · Computer Science 2024-11-20 Eric M. Osterkamp , Dominik Köppl

Long Chain-of-Thought (LCoT), achieved by Reinforcement Learning with Verifiable Rewards (RLVR), has proven effective in enhancing the reasoning capabilities of Large Language Models (LLMs). However, reasoning in current LLMs is primarily…

In this work, we study whether enforcing strict compositional structure in sequence embeddings yields meaningful geometric organization when applied to protein-protein interaction networks. Using Event2Vec, an additive sequence embedding…

Machine Learning · Computer Science 2026-04-02 Antonin Sulc

Data compression plays an important role to deal with high volumes of DNA sequences in the field of Bioinformatics. Again data compression techniques directly affect the alignment of DNA sequences. So the time needed to decompress a…

Computational Engineering, Finance, and Science · Computer Science 2012-11-13 Subhankar Roy , Sunirmal Khatua , Sudipta Roy , Samir K. Bandyopadhyay

A central component of training in Reinforcement Learning (RL) is Experience: the data used for training. The mechanisms used to generate and consume this data have an important effect on the performance of RL algorithms. In this paper, we…

Machine Learning · Computer Science 2021-02-10 Albin Cassirer , Gabriel Barth-Maron , Eugene Brevdo , Sabela Ramos , Toby Boyd , Thibault Sottiaux , Manuel Kroiss

Reinforcement learning (RL) has become an effective approach for fine-tuning large language models (LLMs), particularly to enhance their reasoning capabilities. However, RL fine-tuning remains highly resource-intensive, and existing work…

Machine Learning · Computer Science 2026-02-17 Yifan Sun , Jingyan Shen , Yibin Wang , Tianyu Chen , Zhendong Wang , Mingyuan Zhou , Huan Zhang