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Breast cancer is one of the most challenging global health problems among women. This study investigates the intricate breast tumor microenvironment (TME) dynamics utilizing data from Mammary-specific Polyomavirus Middle T Antigen…

Quantitative Methods · Quantitative Biology 2024-04-11 Navid Mohammad Mirzaei , Panayotis G. Kevrekidis , Leili Shahriyari

Taxonomic classification in biodiversity research involves organizing biological specimens into structured hierarchies based on evidence, which can come from multiple modalities such as images and genetic information. We investigate whether…

The integration of advanced technologies, such as Artificial Intelligence (AI), into manufacturing processes is attracting significant attention, paving the way for the development of intelligent systems that enhance efficiency and…

Neural and Evolutionary Computing · Computer Science 2025-12-09 Mohammadhossein Ghahramani , Yan Qiao , NaiQi Wu , Mengchu Zhou

Omics software tools have reshaped the landscape of modern biology and become an essential component of biomedical research. The increasing dependence of biomedical scientists on these powerful tools creates a need for easier installation…

The problem of inferring proteins from complex peptide samples in shotgun proteomic workflow sets extreme demands on computational resources. This is exacerbated by the fact that, in general, a given protein cannot be defined by a fixed…

Computational Engineering, Finance, and Science · Computer Science 2014-12-31 S. M. Vidanagamachchi , S. D. Dewasurendra , R. G. Ragel , M. Niranjan

Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. We propose a solution for automatically semantifying biological…

Artificial Intelligence · Computer Science 2021-12-03 Marco Anteghini , Jennifer D'Souza , Vitor A. P. Martins dos Santos , Sören Auer

Perception is a critical component of high-integrity applications of robotics and autonomous systems, such as self-driving cars. In these applications, failure of perception systems may put human life at risk, and a broad adoption of these…

Robotics · Computer Science 2020-11-17 Pasquale Antonante , David I. Spivak , Luca Carlone

Due to the diversity and implicit redundancy in terms of processing units and compute kernels, off-the-shelf heterogeneous systems offer the opportunity to detect and tolerate faults during task execution in hardware as well as in software.…

Operating Systems · Computer Science 2014-05-14 Mario Kicherer , Wolfgang Karl

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

With the rapid development of high-throughput sequencing platforms, an increasing number of omics technologies, such as genomics, metabolomics, and transcriptomics, are being applied to disease genetics research. However, biological data…

Genomics · Quantitative Biology 2024-12-18 Lei Xin , Caiyun Huang , Hao Li , Shihong Huang , Yuling Feng , Zhenglun Kong , Zicheng Liu , Siyuan Li , Chang Yu , Fei Shen , Hao Tang

The increasing volumes of data produced by high-throughput instruments coupled with advanced computational infrastructures for scientific computing have enabled what is often called a {\em Fourth Paradigm} for scientific research based on…

Phenotypes are the observable characteristics of an organism arising from its response to the environment. Phenotypes associated with engineered and natural genetic variation are widely recorded using phenotype ontologies in model…

Quantitative Methods · Quantitative Biology 2015-05-26 Robert Hoehndorf , Paul N Schofield , Georgios V Gkoutos

The work is devoted to the development of an information system ISANM that will be useful for teaching students and applicable in the work of engineers and researchers for automating the analysis of colloidal structure morphology. The ISANM…

Soft Condensed Matter · Physics 2025-07-22 Ludia T. Khusainova , Konstantin S. Kolegov

Large systems biology projects can encompass several workgroups often located in different countries. An overview about existing data standards in systems biology and the management, storage, exchange and integration of the generated data…

Databases · Computer Science 2009-12-15 Gerhard Mayer

Molecular communication (MC) provides a foundational framework for information transmission in the Internet of Bio-Nano Things (IoBNT), where efficiency and reliability are crucial. However, the inherent limitations of molecular channels,…

Signal Processing · Electrical Eng. & Systems 2025-04-02 Hanlin Cai , Ozgur B. Akan

The integration of biological principles into artificial olfactory systems has led to significant advancements in odor detection and classification. Inspired by the intricate mechanisms of natural olfaction, researchers are developing…

Neurons and Cognition · Quantitative Biology 2025-02-13 Ravirajan K , Arvind Sundararajan

Semantic similarity measures (SSMs) are widely used in biomedical research but remain underutilized in pharmacovigilance. This study evaluates six ontology-based SSMs for clustering MedDRA Preferred Terms (PTs) in drug safety data. Using…

Computation and Language · Computer Science 2025-04-15 Jeffery L Painter , François Haguinet , Gregory E Powell , Andrew Bate

A bioinformatics platform is introduced aimed at identifying models of disease-specific pathways, as well as a set of network measures that can quantify changes in terms of global structure or single link disruptions.The approach integrates…

Molecular Networks · Quantitative Biology 2012-01-17 A. Barla , S. Riccadonna , S. Masecchia , M. Squillario , M. Filosi , G. Jurman , C. Furlanello

Pathogen control is a critical aspect of modern poultry farming, providing important benefits for both public health and productivity. Effective poultry management measures to reduce pathogen levels in poultry flocks promote food safety by…

Machine Learning · Computer Science 2024-03-04 Ganga Gireesan , Nisha Pillai , Michael J Rothrock , Bindu Nanduri , Zhiqian Chen , Mahalingam Ramkumar

Achieving semantic interoperability across heterogeneous experimental data systems remains a major barrier to data-driven scientific discovery. The Analytical Information Markup Language (AnIML), a flexible XML-based standard for analytical…

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