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Verification bias is a well-known problem that may occur in the evaluation of predictive ability of diagnostic tests. When a binary disease status is considered, various solutions can be found in the literature to correct inference based on…

Methodology · Statistics 2023-04-10 Khanh To Duc , Monica Chiogna , Gianfranco Adimari

The Receiver Operating Characteristic (ROC) surface is a generalization of ROC curve and is widely used for assessment of the accuracy of diagnostic tests on three categories. A complication called the verification bias, meaning that not…

Applications · Statistics 2018-03-20 Rui Zhu , Subhashis Ghosal

In this paper, we propose a mean score equation-based approach to estimate the the volume under the receiving operating characteristic (ROC) surface (VUS) of a diagnostic test, under nonignorable (NI) verification bias. The proposed…

Methodology · Statistics 2019-06-21 Duc-Khanh To , Gianfranco Adimari , Monica Chiogna

The volume under the receiver operating characteristic surface (VUS) is useful for measuring the overall accuracy of a diagnostic test when the possible disease status belongs to one of three ordered categories. In medical studies, the VUS…

Methodology · Statistics 2018-07-03 Khanh To Duc , Monica Chiogna , Gianfranco Adimari

Accurate diagnosis of disease is of great importance in clinical practice and medical research. The receiver operating characteristic (ROC) surface is a popular tool for evaluating the discriminatory ability of continuous diagnostic test…

Methodology · Statistics 2018-05-22 Vanda Inacio de Carvalho , Miguel de Carvalho , Adam Branscum

The ROC curve is the major tool for assessing not only the performance but also the fairness properties of a similarity scoring function. In order to draw reliable conclusions based on empirical ROC analysis, accurately evaluating the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Jean-Rémy Conti , Stéphan Clémençon

The Receiver Operating Characteristic (ROC) curve is a useful tool that measures the discriminating power of a continuous variable or the accuracy of a pharmaceutical or medical test to distinguish between two conditions or classes. In…

Methodology · Statistics 2022-07-26 Ana M. Bianco , Graciela Boente , Wenceslao Gonzalez-Manteiga

Test-time scaling aims to improve language model performance by leveraging additional compute during inference. Many works have empirically studied techniques such as Best-of-N (BoN) and Rejection Sampling (RS) that make use of a verifier…

Machine Learning · Computer Science 2025-10-13 Florian E. Dorner , Yatong Chen , André F. Cruz , Fanny Yang

Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between diseased and nondiseased states must be…

Methodology · Statistics 2018-06-05 Vanda Inacio de Carvalho , Maria Xose Rodriguez-Alvarez

To evaluate a classification algorithm, it is common practice to plot the ROC curve using test data. However, the inherent randomness in the test data can undermine our confidence in the conclusions drawn from the ROC curve, necessitating…

Methodology · Statistics 2024-05-22 Zheshi Zheng , Bo Yang , Peter Song

The empirical likelihood is a powerful nonparametric tool, that emulates its parametric counterpart -- the parametric likelihood -- preserving many of its large-sample properties. This article tackles the problem of assessing the…

Methodology · Statistics 2023-05-29 Duc-Khanh To , Gianfranco Adimari , Monica Chiogna

To assess the classification accuracy of a continuous diagnostic result, the receiver operating characteristic (ROC) curve is commonly used in applications. The partial area under the ROC curve (pAUC) is one of widely accepted summary…

Applications · Statistics 2011-03-11 Hung Hung , Chin-Tsang Chiang

In diagnostic studies, researchers frequently encounter imperfect reference standards with some misclassified labels. Treating these as gold standards can bias receiver operating characteristic (ROC) curve analysis. To address this issue,…

Methodology · Statistics 2025-02-13 Yifan Sun , Peijun Sang , Qinglong Tian , Pengfei Li

Many problems that appear in biomedical decision making, such as diagnosing disease and predicting response to treatment, can be expressed as binary classification problems. The costs of false positives and false negatives vary across…

When evaluating medical tests or biomarkers for disease classification, the area under the receiver-operating characteristic (ROC) curve is a widely used performance metric that does not require us to commit to a specific decision…

Methodology · Statistics 2013-10-21 Wanhua Su , Yan Yuan , Mu Zhu

We propose new simultaneous inference methods for diagnostic trials with elaborate factorial designs. Instead of the commonly used total area under the receiver operating characteristic (ROC) curve, our parameters of interest are partial…

Statistics Theory · Mathematics 2023-02-22 Maximilian Wechsung , Frank Konietschke

The summary receiver operating characteristic (SROC) curve has been recommended as one important meta-analytical summary to represent the accuracy of a diagnostic test in the presence of heterogeneous cutoff values. However, selective…

Methodology · Statistics 2024-01-11 Yi Zhou , Ao Huang , Satoshi Hattori

While the area under the ROC curve is perhaps the most common measure that is used to rank the relative performance of different binary classifiers, longstanding field folklore has noted that it can be a measure that ill-captures the…

Machine Learning · Computer Science 2024-12-19 Christopher Ratigan , Lenore Cowen

The comparison of Receiver Operating Characteristic (ROC) curves is frequently used in the literature to compare the discriminatory capability of different classification procedures based on diagnostic variables. The performance of these…

Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant…

Methodology · Statistics 2022-02-01 Paul N. Patrone , Anthony J. Kearsley
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