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Inference for mechanistic models is challenging because of nonlinear interactions between model parameters and a lack of identifiability. Here we focus on a specific class of mechanistic models, which we term stable differential equations.…

Computation · Statistics 2017-12-13 Philip Maybank , Ingo Bojak , Richard G. Everitt

This study conducts a comparative analysis of stochastic and deterministic models to better understand the dynamics of the HIV epidemic across genders. By incorporating gender-specific transmission probabilities and treatment uptake rates,…

Populations and Evolution · Quantitative Biology 2025-01-30 Nuzhat Nuari Khan Rivu , Md Kamrujjaman , Shohel Ahmed

It is the main purpose of this paper to introduce a graph-valued stochastic process in order to model the spread of a communicable infectious disease. The major novelty of the SIR model we promote lies in the fact that the social network on…

Applications · Statistics 2014-02-06 Charanpal Dhanjal , Stéphan Clémençon

Motivated by analogies between the spreading of human-to-human infections and of chemical processes, we develop a comprehensive model that accounts both for infection and for transport. In this analogy, the three different populations of…

Populations and Evolution · Quantitative Biology 2020-12-08 Harisankar Ramaswamy , Assad A Oberai , Yannis C Yortsos

A model describing the dynamics related to the spreading of non-lethal infectious diseases in a fixed-size population is proposed. The model consists of a non-linear delay-differential equation describing the time evolution of the increment…

Populations and Evolution · Quantitative Biology 2010-10-05 A. Noviello , F. Romeo , R. De Luca

Households play an important role in disease dynamics. Many infections happening there due to the close contact, while mitigation measures mainly target the transmission between households. Therefore, one can see households as boosting the…

Populations and Evolution · Quantitative Biology 2025-01-22 Philipp Doenges , Thomas Götz , Tyll Krueger , Karol Niedzielewski , Viola Priesemann , Moritz Schaefer

The study of infectious disease propagation is essential for understanding and controlling epidemics. One of the most useful tools for gaining insights into the spread of infectious diseases is mathematical modelling. In terms of…

This study utilizes mathematical models to assess progress toward achieving the UNAIDS 90-90-90 and 95-95-95 targets aimed at managing and eradicating HIV/AIDS. It contrasts stochastic and deterministic models, focusing on their utility in…

Other Quantitative Biology · Quantitative Biology 2025-03-12 Nuzhat Nuari Khan Rivu , Md Kamrujjaman , Asif Iqbal

In this paper we study the susceptible-infectious (SI) epidemiological model using dynamical graphs. Dynamical structures have been recently applied in many areas including complex systems. Dynamical structures include the mutual…

Populations and Evolution · Quantitative Biology 2011-10-19 Jose L. Herrera , Gilberto Gonzalez-Parra

Strategic test allocation plays a major role in the control of both emerging and existing pandemics (e.g., COVID-19, HIV). Widespread testing supports effective epidemic control by (1) reducing transmission via identifying cases, and (2)…

Methodology · Statistics 2022-12-06 Ivana Malenica , Jeremy R. Coyle , Mark J. van der Laan , Maya L. Petersen

The SIR model with spatially inhomogeneous infection rate is studied with numerical simulations in one, two, and three dimensions, considering the case that the infection spreads inhomogeneously in densely populated regions or hot spots. We…

Medical Physics · Physics 2020-12-25 Hidetsugu Sakaguchi , Yuta Nakao

This study examined a simulated confined space modelled as a hospital waiting area, where people who could have underlying conditions congregate and mix with potentially infectious individuals. It further investigated the impact of the…

Multiagent Systems · Computer Science 2021-05-24 J. A. Sarumi , E. C. Onwubiko , O. L. A. Ogunjimi

In this document, we report our proposal for modeling the risk of possible contagiousity in a given area monitored by RGB cameras where people freely move and interact. Our system, called Inter-Homines, evaluates in real-time the contagion…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Matteo Fabbri , Fabio Lanzi , Riccardo Gasparini , Simone Calderara , Lorenzo Baraldi , Rita Cucchiara

The aims of this work is to analyse of the global stability of the extended model of hepatitis C virus(HCV) infection with cellular proliferation, spontaneous cure and hepatocyte homeostasis. We first give general information about…

Dynamical Systems · Mathematics 2019-05-08 Alexis Nangue , Cyprien Fokoue , Raoue Poumeni

In recent years, mathematical models have become an indispensable tool in the planning, evaluation, and implementation of public health interventions. Models must often provide detailed information for many levels of population…

Dynamical Systems · Mathematics 2024-06-05 Alex Viguerie , Chiara Piazzola , Md Hafizul Islam , Evin Uzun Jacobson

This paper is about numerical control of HIV propagation. The contribution of the paper is threefold: first, a novel model of HIV propagation is proposed; second, the methods from numerical optimal control are successfully applied to the…

Systems and Control · Computer Science 2023-05-30 Dmitry Gromov , Ingo Bulla , Ethan O. Romero-Severson , Oana Silvia Serea

The contact process is an emblematic model of a non-equilibrium system, containing a phase transition between inactive and active dynamical regimes. In the epidemiological context, the model is known as the susceptible-infected-susceptible…

Statistical Mechanics · Physics 2023-05-12 Wout Merbis , Clélia de Mulatier , Philippe Corboz

Planning, implementation and evaluation of public health policies to control the human immunodeficiency virus (HIV) epidemic require regular monitoring of disease burden. This includes the proportion living with HIV, whether diagnosed or…

Methodology · Statistics 2014-05-20 Daniela De Angelis , Anne M. Presanis , Stefano Conti , A. E. Ades

We study the early stages of viral infection, and the distribution of times to obtain a persistent infection. The virus population proliferates by entering and reproducing inside a target cell until a sufficient number of new virus…

Populations and Evolution · Quantitative Biology 2019-07-11 Carmel Sagi , Michael Assaf

We investigate an epidemic model based on Bailey's continuous differential system. In the continuous time domain, we extend the classical model to time-dependent coefficients and present an alternative solution method to Gleissner's…

Classical Analysis and ODEs · Mathematics 2019-01-01 Martin Bohner , Sabrina Streipert , Delfim F. M. Torres
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