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We study the equilibrium conformations of a lipid domain on a planar fluid membrane where the domain is decorated by a vector field representing the tilt of the stiff fatty acid chains of the lipid molecules, while the surrounding membrane…

Soft Condensed Matter · Physics 2009-11-07 R. C Sarasij , Madan Rao

Thin cylindrical tethers are common lipid bilayer membrane structures, arising in situations ranging from micromanipulation experiments on artificial vesicles to the dynamic structure of the Golgi apparatus. We study the shape and formation…

Soft Condensed Matter · Physics 2009-11-07 Thomas R. Powers , Greg Huber , Raymond E. Goldstein

We study the dynamic structure of lipid domain inclusions embedded within a phase-separated reconstituted lipid bilayer in contact with a swarming flow of gliding filamentous actin. Passive circular domains transition into highly-deformed…

Soft Condensed Matter · Physics 2024-06-12 Aakanksha Gubbala , Daniel P. Arnold , Anika Jena , Stephanie Anujarerat , Sho C. Takatori

Living and engineered systems rely on the stable coexistence of two interspersed liquid phases. Yet surface tension drives their complete separation. Here we show that stable droplets of uniform and tuneable size can be produced through…

The line tension of an electrolyte wetting a non-polar substrate is computed analytically and numerically. The results show that, depending on the value of the apparent contact angle, positive or negative line tension values may be…

Chemical Physics · Physics 2014-11-06 Aaron Dörr , Steffen Hardt

We simulate a phase-separating a bilayer in which the leaflets experience a direct coupling favouring local compositional symmetry ("registered" bilayer phases), and an indirect coupling due to hydrophobic mismatch that favours strong local…

Soft Condensed Matter · Physics 2016-04-12 John J. Williamson , Peter D. Olmsted

In this paper, we examine the mechanical role of the lipid bilayer in ion channel conformation and function with specific reference to the case of the mechanosensitive channel of large conductance (MscL). In a recent paper (Wiggins and…

Biomolecules · Quantitative Biology 2009-11-10 Paul Wiggins , Rob Phillips

The spatio-temporal organization of proteins and the associated morphological changes in membranes are of importance in cell signaling. Several mechanisms that promote the aggregation of proteins at low cell surface concentrations have been…

Biological Physics · Physics 2018-04-18 K. K. Sreeja , P. B. Sunil Kumar

Common models for two-phase lipid bilayer membranes are based on an energy that consists of an elastic term for each lipid phase and a line energy at interfaces. Although such an energy controls only the length of interfaces, the membrane…

Analysis of PDEs · Mathematics 2016-03-10 Michael Helmers

Transition towards spatio-temporal chaos in one-dimensional interfacial patterns often involves two degrees of freedom: drift and out-of-phase oscillations of cells, respectively associated to parity breaking and vacillating-breathing…

Condensed Matter · Physics 2007-05-23 Philippe Brunet , Jean-Marc Flesselles , Laurent Limat

The growth of viscous two-dimensional lipid domains in contact with a viscoelastic actin network was recently shown to exhibit unusual lipid domain ripening due to the geometry and anisotropy of the actin network [Arnold & Takatori.…

Soft Condensed Matter · Physics 2025-07-08 Aakanksha Gubbala , Anika M. Jena , Daniel P. Arnold , Sho C. Takatori

Liposomes that achieve a heterogeneous and spatially organized surface through phase separation have been recognized to be a promising platform for delivery purposes. However, their design and optimization through experimentation can be…

Soft Condensed Matter · Physics 2021-11-05 Y. Wang , Y. Palzhanov , A. Quaini , M. Olshanskii , S. Majd

The newly-discovered ferroelectric nematic liquid crystal exhibits a variety of unique defect phenomena. The depolarization field in the material favors spontaneous spatial variations in polarization, manifesting in diverse forms such as…

Soft Condensed Matter · Physics 2025-07-17 Maxim O. Lavrentovich , Priyanka Kumari , Oleg D. Lavrentovich

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

Soft Condensed Matter · Physics 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

We analyze two representative systems containing a three-phase-contact line: a liquid lens at a fluid--fluid interface and a liquid drop in contact with a gas phase residing on a solid substrate. We discuss to which extent the decomposition…

Soft Condensed Matter · Physics 2009-11-13 L. Schimmele , M. Napiorkowski , S. Dietrich

Response of lipid bilayers to external mechanical stimuli is an active area of research with implications for fundamental and synthetic cell biology. However, there is a lack of tools for systematically imposing mechanical strains and…

Line tension in wetting processes is of high scientific and technological relevance, but its understanding remains vague, mainly because of its difficult determination. A widely used method to extract the line tension relies on the…

Soft Condensed Matter · Physics 2022-11-24 Fabio Staniscia , Matej Kanduč

Finite domains of a Langmuir monolayer in a phase with tilted molecules can be modeled by a simple elastic free energy of an XY order parameter with isotropic and anisotropic line tension terms. The domains can and often do contain…

Soft Condensed Matter · Physics 2016-08-31 David Pettey , T. C. Lubensky

Considering two rigid conical inclusions embedded in a membrane subject to lateral tension, we study the membrane-mediated interaction between these inclusions that originates from the hat-shaped membrane deformations associated with the…

Soft Condensed Matter · Physics 2009-10-31 T. R. Weikl , M. M. Kozlov , W. Helfrich

A lipid coated bubble (LCB) oscillator is a very interesting non-smooth oscillator with many important applications ranging from industry and chemistry to medicine. However, due to the complex behavior of the coating intermixed with the…

Fluid Dynamics · Physics 2021-07-28 AJ Sojahrood , H. Haghi , T. M. Porter , R. Karshafian , M. C. Kolios