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One cannot yet point to any firm string prediction. While many approximate string ground states are known with interesting properties, we do not have any argument that one or another describes what we observe around us, and for reasons…

High Energy Physics - Phenomenology · Physics 2017-08-23 Michael Dine

One of the central problems in the classification of individual test sequences (e.g. genetic analysis), is that of checking for the similarity of sample test sequences as compared with a set of much longer training sequences. This is done…

Information Theory · Computer Science 2014-06-24 Jacob Ziv

We consider the problem of efficiently designing sets (codes) of equal-length DNA strings (words) that satisfy certain combinatorial constraints. This problem has numerous motivations including DNA computing and DNA self-assembly. Previous…

Data Structures and Algorithms · Computer Science 2007-05-23 Ming-Yang Kao , Manan Sanghi , Robert Schweller

We continue and extend previous work on the parameterized complexity analysis of the NP-hard Stable Roommates with Ties and Incomplete Lists problem, thereby strengthening earlier results both on the side of parameterized hardness as well…

Computational Complexity · Computer Science 2021-03-09 Robert Bredereck , Klaus Heeger , Dušan Knop , Rolf Niedermeier

Genetic Programming (GP) has found various applications. Understanding this type of algorithm from a theoretical point of view is a challenging task. The first results on the computational complexity of GP have been obtained for problems…

Neural and Evolutionary Computing · Computer Science 2011-05-09 Markus Wagner , Frank Neumann

Pattern matching queries on strings can be solved in linear time by Knuth-Morris-Pratt (KMP) algorithm. In 1973, Weiner introduced the suffix tree of a string [FOCS 1973] and showed that the seemingly more difficult problem of computing…

Data Structures and Algorithms · Computer Science 2024-02-27 Nicola Cotumaccio

The key finding in the DNA double helix model is the specific pairing or binding between nucleotides A-T and C-G, and the pairing rules are the molecule basis of genetic code. Unfortunately, no such rules have been discovered for proteins.…

Biomolecules · Quantitative Biology 2017-02-28 Yuhong Wang , Junzhou Huang , Wei Li , Sheng Wang , Chuanfan Ding

Algorithms to find optimal alignments among strings, or to find a parsimonious summary of a collection of strings, are well studied in a variety of contexts, addressing a wide range of interesting applications. In this paper, we consider…

Social and Information Networks · Computer Science 2020-11-09 Patty Commins , David Liben-Nowell , Tina Liu , Kiran Tomlinson

The Set Packing problem is, given a collection of sets $\mathcal{S}$ over a ground set $\mathcal{U}$, to find a maximum collection of sets that are pairwise disjoint. The problem is among the most fundamental NP-hard optimization problems…

Computational Complexity · Computer Science 2023-02-28 Ameet Gadekar

The minimum common string partition problem is an NP-hard combinatorial optimization problem with applications in computational biology. In this work we propose the first integer linear programming model for solving this problem. Moreover,…

Artificial Intelligence · Computer Science 2014-05-23 Christian Blum , José A. Lozano , Pedro Pinacho Davidson

Phylogenetic mixture models are statistical models of character evolution allowing for heterogeneity. Each of the classes in some unknown partition of the characters may evolve by different processes, or even along different trees. The…

Populations and Evolution · Quantitative Biology 2010-11-19 John A. Rhodes , Seth Sullivant

We study a new variant of the string matching problem called cross-document string matching, which is the problem of indexing a collection of documents to support an efficient search for a pattern in a selected document, where the pattern…

Data Structures and Algorithms · Computer Science 2012-06-21 Gregory Kucherov , Yakov Nekrich , Tatiana Starikovskaya

This is a review of a set of recent papers with some new data added. After a brief biological introduction a visualization scheme of the string composition of long DNA sequences, in particular, of bacterial complete genomes, will be…

Soft Condensed Matter · Physics 2009-10-31 Bai-lin Hao

Searching for all occurrences of a pattern in a text is a fundamental problem in computer science with applications in many other fields, like natural language processing, information retrieval and computational biology. Sampled string…

Data Structures and Algorithms · Computer Science 2019-08-19 Simone Faro , Arianna Pavone , Francesco Pio Marino

The set splittability problem is the following: given a finite collection of finite sets, does there exits a single set that contains exactly half the elements from each set in the collection? (If a set has odd size, we allow the floor or…

Combinatorics · Mathematics 2019-09-17 Peter Bernstein , Cashous Bortner , Samuel Coskey , Shuni Li , Connor Simpson

Biological and machine pattern recognition systems face a common challenge: Given sensory data about an unknown object, classify the object by comparing the sensory data with a library of internal representations stored in memory. In many…

Information Theory · Computer Science 2007-07-13 M. Brandon Westover , Joseph A. O'Sullivan

Fixed-parameter tractability analysis and scheduling are two core domains of combinatorial optimization which led to deep understanding of many important algorithmic questions. However, even though fixed-parameter algorithms are appealing…

Data Structures and Algorithms · Computer Science 2013-11-19 Matthias Mnich , Andreas Wiese

We address the problem of counting the number of strings in a collection where a given pattern appears, which has applications in information retrieval and data mining. Existing solutions are in a theoretical stage. We implement these…

Data Structures and Algorithms · Computer Science 2015-10-02 Travis Gagie , Aleksi Hartikainen , Juha Kärkkäinen , Gonzalo Navarro , Simon J. Puglisi , Jouni Sirén

It is well known that computing a minimum DFA consistent with a given set of positive and negative examples is NP-hard. Previous work has identified conditions on the input sample under which the problem becomes tractable or remains hard.…

Formal Languages and Automata Theory · Computer Science 2026-01-21 Radu Cosmin Dumitru , Ryo Yoshinaka , Ayumi Shinohara

In a simple pattern matching problem one has a pattern $w$ and a text $t$, which are words over a finite alphabet $\Sigma$. One may ask whether $w$ occurs in $t$, and if so, where? More generally, we may have a set $P$ of patterns and a set…

Formal Languages and Automata Theory · Computer Science 2018-11-06 Janusz A. Brzozowski , Sylvie Davies , Abhishek Madan