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High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

Uncertainty estimation, which provides a means of building explainable neural networks for medical imaging applications, have mostly been studied for single deep learning models that focus on a specific task. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Leonhard F. Feiner , Martin J. Menten , Kerstin Hammernik , Paul Hager , Wenqi Huang , Daniel Rueckert , Rickmer F. Braren , Georgios Kaissis

Optical imaging of the brain has expanded dramatically in the past two decades. New optics, indicators, and experimental paradigms are now enabling in-vivo imaging from the synaptic to the cortex-wide scales. To match the resulting flood of…

Image and Video Processing · Electrical Eng. & Systems 2024-02-15 Gal Mishne , Adam Charles

Complex systems are fascinating because their rich macroscopic properties emerge from the interaction of many simple parts. Understanding the building principles of these emergent phenomena in nature requires assessing natural complex…

Neurons and Cognition · Quantitative Biology 2022-11-17 Anna Levina , Viola Priesemann , Johannes Zierenberg

In recent years, neuroscience has made significant progress in building large-scale artificial neural network (ANN) models of brain activity and behavior. However, there is no consensus on the most efficient ways to collect data and design…

Large-scale neuroscience is generating rich datasets across animals, brain areas and behavioral contexts, yet our modeling efforts remains fragmented across isolated experiments. We argue that understanding behavior requires integrative…

Network datasets appear across a wide range of scientific fields, including biology, physics, and the social sciences. To enable data-driven discoveries from these networks, statistical inference techniques like estimation and hypothesis…

Methodology · Statistics 2026-02-19 Arpan Kumar , Minh Tang , Srijan Sengupta

Deep learning has achieved significant breakthroughs in medical imaging, but these advancements are often dependent on large, well-annotated datasets. However, obtaining such datasets poses a significant challenge, as it requires…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Siteng Ma , Honghui Du , Yu An , Jing Wang , Qinqin Wang , Haochang Wu , Aonghus Lawlor , Ruihai Dong

Although deep learning models like CNNs have achieved great success in medical image analysis, the small size of medical datasets remains a major bottleneck in this area. To address this problem, researchers have started looking for…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Xiaozheng Xie , Jianwei Niu , Xuefeng Liu , Zhengsu Chen , Shaojie Tang , Shui Yu

Traditionally, training neural networks to perform semantic segmentation required expensive human-made annotations. But more recently, advances in the field of unsupervised learning have made significant progress on this issue and towards…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Leon Sick , Dominik Engel , Pedro Hermosilla , Timo Ropinski

NeuroNet is a deep convolutional neural network mimicking multiple popular and state-of-the-art brain segmentation tools including FSL, SPM, and MALPEM. The network is trained on 5,000 T1-weighted brain MRI scans from the UK Biobank Imaging…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Martin Rajchl , Nick Pawlowski , Daniel Rueckert , Paul M. Matthews , Ben Glocker

Neurosymbolic Programming (NP) techniques have the potential to accelerate scientific discovery. These models combine neural and symbolic components to learn complex patterns and representations from data, using high-level concepts or known…

Knowledge discovery is hindered by the increasing volume of publications and the scarcity of extensive annotated data. To tackle the challenge of information overload, it is essential to employ automated methods for knowledge extraction and…

Artificial Intelligence · Computer Science 2025-04-15 Christos Theodoropoulos , Andrei Catalin Coman , James Henderson , Marie-Francine Moens

The study of neurocognitive tasks requiring accurate localisation of activity often rely on functional Magnetic Resonance Imaging, a widely adopted technique that makes use of a pipeline of data processing modules, each involving a variety…

Computer Vision and Pattern Recognition · Computer Science 2016-10-14 Albert Vilamala , Kristoffer Hougaard Madsen , Lars Kai Hansen

To put a state-of-the-art neural network to practical use, it is necessary to design a model that has a good trade-off between the resource consumption and performance on the test set. Many researchers and engineers are developing methods…

Machine Learning · Computer Science 2020-09-15 SeongUk Park , KiYoon Yoo , Nojun Kwak

Reconstructing a map of neuronal connectivity is a critical challenge in contemporary neuroscience. Recent advances in high-throughput serial section electron microscopy (EM) have produced massive 3D image volumes of nanoscale brain tissue…

As machine learning continues to gain momentum in the neuroscience community, we witness the emergence of novel applications such as diagnostics, characterization, and treatment outcome prediction for psychiatric and neurological disorders,…

Computer Vision and Pattern Recognition · Computer Science 2018-04-27 Maxim Sharaev , Alexander Andreev , Alexey Artemov , Alexander Bernstein , Evgeny Burnaev , Ekaterina Kondratyeva , Svetlana Sushchinskaya , Renat Akzhigitov

Embedding is a common technique for analyzing multi-dimensional data. However, the embedding projection cannot always form significant and interpretable visual structures that foreshadow underlying data patterns. We propose an approach that…

Human-Computer Interaction · Computer Science 2022-09-26 Jie Li , Chun-qi Zhou

Sampling from unnormalized densities presents a fundamental challenge with wide-ranging applications, from posterior inference to molecular dynamics simulations. Continuous flow-based neural samplers offer a promising approach, learning a…

Machine Learning · Computer Science 2025-07-22 Wuhao Chen , Zijing Ou , Yingzhen Li

Smart microscopy represents a paradigm shift in biological imaging, moving from passive observation tools to active collaborators in scientific inquiry. Enabled by advances in automation, computational power, and artificial intelligence,…

Artificial Intelligence · Computer Science 2025-05-28 P. S. Kesavan , Pontus Nordenfelt
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