Related papers: metaSPAdes: a new versatile de novo metagenomics a…
Novel multimodal imaging methods are capable of generating extensive, super high resolution datasets for preclinical research. Yet, a massive lack of annotations prevents the broad use of deep learning to analyze such data. So far, existing…
In recent years, several models have improved the capacity to generate synthetic tabular datasets. However, such models focus on synthesizing simple columnar tables and are not useable on real-life data with complex structures. This paper…
The advances of next-generation sequencing technology have accelerated study of the microbiome and stimulated the high throughput profiling of metagenomes. The large volume of sequenced data has encouraged the rise of various studies for…
Taxonomic classification in biodiversity research involves organizing biological specimens into structured hierarchies based on evidence, which can come from multiple modalities such as images and genetic information. We investigate whether…
Despite extensive research spanning several decades, class imbalance is still considered a profound difficulty for both machine learning and deep learning models. While data oversampling is the foremost technique to address this issue,…
Stacking (or stacked generalization) is an ensemble learning method with one main distinctiveness from the rest: even though several base models are trained on the original data set, their predictions are further used as input data for one…
Data sets are growing in complexity thanks to the increasing facilities we have nowadays to both generate and store data. This poses many challenges to machine learning that are leading to the proposal of new methods and paradigms, in order…
Deep learning-based antimicrobial peptide (AMP) discovery faces critical challenges such as limited controllability, lack of representations that efficiently model antimicrobial properties, and low experimental hit rates. To address these…
DNA microarrays are a relatively new technology that can simultaneously measure the expression level of thousands of genes. They have become an important tool for a wide variety of biological experiments. One of the most common goals of DNA…
The detection of genomic structural variation (SV) has advanced tremendously in recent years due to progress in high-throughput sequencing technologies. Novel sequence insertions, insertions without similarity to a human reference genome,…
Within the paradigm of metamaterials and metasurfaces, electromagnetic properties of composite materials can be engineered by shaping or modulating their constituents, so-called meta-atoms. Synthesis and analysis of complex-shape meta-atoms…
Metagenomics is an emerging field of molecular biology concerned with analyzing the genomes of environmental samples comprising many different diverse organisms. Given the nature of metagenomic data, one usually has to sequence the genomic…
Since data is the fuel that drives machine learning models, and access to labeled data is generally expensive, semi-supervised methods are constantly popular. They enable the acquisition of large datasets without the need for too many…
Simulated microbial communities are used in benchmarking microbial abundance estimators and other bioinformatic utilities. To match current data scales, large simulated samples are needed, and many. The speed of current implementations…
Image synthesis is currently one of the most addressed image processing topic in computer vision and deep learning fields of study. Researchers have tackled this problem focusing their efforts on its several challenging problems, e.g. image…
As the sequencing costs are decreasing, there is great incentive to perform large scale association studies to increase power of detecting new variants. Federated association testing among different institutions is a viable solution for…
Antibiotic resistance presents a growing global health crisis, demanding new therapeutic strategies that target novel bacterial mechanisms. Recent advances in protein structure prediction and machine learning-driven molecule generation…
This paper describes a new method, Combi-bootstrap, to exploit existing taggers and lexical resources for the annotation of corpora with new tagsets. Combi-bootstrap uses existing resources as features for a second level machine learning…
The future of computing systems is inevitably embracing a disaggregated and composable pattern: from clusters of computers to pools of resources that can be dynamically combined together and tailored around applications requirements.…
Phylogenetic placement refers to a family of tools and methods to analyze, visualize, and interpret the tsunami of metagenomic sequencing data generated by high-throughput sequencing. Compared to alternative (e. g., similarity-based)…