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This proof-of-concept study introduces a novel multimodal framework combining synchronized EEG-fNIRS modalities with neuronal avalanche analysis to identify early network dysfunction in Alzheimer's disease. The approach leverages…

Neurons and Cognition · Quantitative Biology 2026-03-25 Eva Guttmann-Flury , Yun-Hsuan Chen , Qiaoyuan Xiang , Hao Zhang , Mohamad Sawan

Functional brain networks exhibit dynamics on the sub-second temporal scale and are often assumed to embody the physiological substrate of cognitive processes. Here we analyse the temporal and spatial dynamics of these states, as measured…

Neurons and Cognition · Quantitative Biology 2016-06-09 Tammo Rukat , Adam Baker , Andrew Quinn , Mark Woolrich

Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

Optimization and Control · Mathematics 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

The classification of harmful brain activities, such as seizures and periodic discharges, play a vital role in neurocritical care, enabling timely diagnosis and intervention. Electroencephalography (EEG) provides a non-invasive method for…

Machine Learning · Computer Science 2025-10-21 Shivraj Singh Bhatti , Aryan Yadav , Mitali Monga , Neeraj Kumar

A key technology enabling the success of catheter ablation treatment for atrial tachycardia is activation mapping, which relies on manual local activation time (LAT) annotation of all acquired intracardiac electrogram (EGM) signals. This is…

Signal Processing · Electrical Eng. & Systems 2022-06-16 Zerui Chen , Sonia Xhyn Teo , Andrie Ochtman , Shier Nee Saw , Nicholas Cheng , Eric Tien Siang Lim , Murphy Lyu , Hwee Kuan Lee

Explaining individual differences in cognitive abilities requires both identifying brain parameters that vary across individuals and understanding how brain networks are recruited for specific tasks. Typically, task performance relies on…

Neurons and Cognition · Quantitative Biology 2026-05-05 Sida Chen , Siqi Yang , Zhao Chang , Taro Toyoizumi , Werner Sommer , Lianchun Yu , Qian-Yuan Tang , Changsong Zhou

Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…

Neurons and Cognition · Quantitative Biology 2025-09-24 Ali Khazaee , Abdolreza Mohammadi , Ruairi O'Reilly

Given a spatio-temporal network (ST network) where edge properties vary with time, a time-sub-interval minimum spanning tree (TSMST) is a collection of minimum spanning trees of the ST network, where each tree is associated with a time…

Data Structures and Algorithms · Computer Science 2010-05-24 Viswanath Gunturi , Shashi Shekhar , Arnab Bhattacharya

This study explores the intersection of electroencephalography (EEG) microstates and Large Language Models (LLMs) to enhance the assessment of cognitive load states. By utilizing EEG microstate features, the research aims to fine-tune LLMs…

Human-Computer Interaction · Computer Science 2025-08-12 Bujar Raufi

Electroencephalography (EEG) signals are crucial for investigating brain function and cognitive processes. This study aims to address the challenges of efficiently recording and analyzing high-dimensional EEG signals while listening to…

Machine Learning · Computer Science 2024-08-23 Jingyi Wang , Zhiqun Wang , Guiran Liu

We consider the problem of predicting edges in a graph from node attributes in an e-commerce setting. Specifically, given nodes labelled with search query text, we want to predict links to related queries that share products. Experiments…

Machine Learning · Computer Science 2020-06-15 Matthew Dippel , Adam Kiezun , Tanay Mehta , Ravi Sundaram , Srikanth Thirumalai , Akshar Varma

Mental disorders present challenges in diagnosis and treatment due to their complex and heterogeneous nature. Electroencephalogram (EEG) has shown promise as a potential biomarker for these disorders. However, existing methods for analyzing…

Methodology · Statistics 2024-01-30 Xingche Guo , Bin Yang , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Network analysis of human brain connectivity is critically important for understanding brain function and disease states. Embedding a brain network as a whole graph instance into a meaningful low-dimensional representation can be used to…

Machine Learning · Computer Science 2018-07-26 Ye Liu , Lifang He , Bokai Cao , Philip S. Yu , Ann B. Ragin , Alex D. Leow

Electroencephalography (EEG) offers non-invasive, real-time mental workload assessment, which is crucial in high-stakes domains like aviation and medicine and for advancing brain-computer interface (BCI) technologies. This study introduces…

Human-Computer Interaction · Computer Science 2025-06-11 Gourav Siddhad , Partha Pratim Roy , Byung-Gyu Kim

Alzheimer's Disease is a progressive neurological disorder that is one of the most common forms of dementia. It leads to a decline in memory, reasoning ability, and behavior, especially in older people. The cause of Alzheimer's Disease is…

Machine Learning · Computer Science 2025-04-03 Jing Wang , Jun-En Ding , Feng Liu , Elisa Kallioniemi , Shuqiang Wang , Wen-Xiang Tsai , Albert C. Yang

Topological data analysis (TDA) has become a powerful approach over the last twenty years, mainly due to its ability to capture the shape and the geometry inherent in the data. Persistence homology, which is a particular tool in TDA, has…

Neurons and Cognition · Quantitative Biology 2024-01-12 Anass B. El-Yaagoubi , Shuhao Jiao , Moo K. Chung , Hernando Ombao

Region-based methods have proven necessary for improving segmentation accuracy of neuronal structures in electron microscopy (EM) images. Most region-based segmentation methods use a scoring function to determine region merging. Such…

Computer Vision and Pattern Recognition · Computer Science 2018-04-04 Ting Liu , Miaomiao Zhang , Mehran Javanmardi , Nisha Ramesh , Tolga Tasdizen

Many studies have analyzed working memory (WM) from electroencephalogram (EEG). However, little is known about changes in the brain neurodynamics among resting-state (RS) according to the WM process. Here, we identified frequency-specific…

Neurons and Cognition · Quantitative Biology 2022-12-13 Gi-Hwan Shin , Young-Seok Kweon , Heon-Gyu Kwak

Autism is one of the most important neurological disorders which leads to problems in a person's social interactions. Improvement of brain imaging technologies and techniques help us to build brain structural and functional networks.…

Machine Learning · Computer Science 2021-03-26 Mohammad Amin , Farshad Safaei

Aperiodic neural activity has been the subject of intense research interest lately as it could reflect on the cortical excitation/inhibition ratio, which is suspected to be affected in numerous clinical conditions. This phenomenon is…

Neurons and Cognition · Quantitative Biology 2025-06-02 Frigyes Samuel Racz , John Milton , Juan Luis Cabrera , Gábor Csukly , José del R. Millán