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To enhance Large Language Models' (LLMs) reliability, calibration is essential -- the model's assessed confidence scores should align with the actual likelihood of its responses being correct. However, current confidence elicitation methods…

Computation and Language · Computer Science 2024-10-29 Yukun Huang , Yixin Liu , Raghuveer Thirukovalluru , Arman Cohan , Bhuwan Dhingra

De Bruijn graph is one of the most important data structures used in de-novo genome assembly algorithms, especially for NGS data. There is a growing need for parallel data structures and algorithms due to the increasing number of cores in…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-08 Daniel Górniak , Robert Nowak

Low-Rank Adaptation (LoRA) has emerged as a widely adopted technique in text-to-image models, enabling precise rendering of multiple distinct elements, such as characters and styles, in multi-concept image generation. However, current…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Xiandong Zou , Mingzhu Shen , Christos-Savvas Bouganis , Yiren Zhao

Iterating with new and improved OCR solutions enforces decision making when it comes to targeting the right candidates for reprocessing. This especially applies when the underlying data collection is of considerable size and rather diverse…

Computation and Language · Computer Science 2023-06-22 Pit Schneider , Yves Maurer

Automated labeling of chest X-ray reports is essential for enabling downstream tasks such as training image-based diagnostic models, population health studies, and clinical decision support. However, the high variability, complexity, and…

Computation and Language · Computer Science 2025-05-06 Brian Wong , Kaito Tanaka

Owing to its several merits over other DNA sequencing technologies, nanopore sequencers hold an immense potential to revolutionize the efficiency of DNA storage systems. However, their higher error rates necessitate further research to…

Information Theory · Computer Science 2024-05-08 Anisha Banerjee , Yonatan Yehezkeally , Antonia Wachter-Zeh , Eitan Yaakobi

The formal version of our work has been published in BMC Bioinformatics and can be found here: http://www.biomedcentral.com/1471-2105/13/S6/S1 Motivation: To tackle the problem of huge memory usage associated with de Bruijn graph-based…

Data Structures and Algorithms · Computer Science 2013-01-10 Chengxi Ye , Charles H. Cannon , Zhanshan Sam Ma , Douglas W. Yu , Mihai Pop

Low-Rank Adaptation (LoRA) is a crucial method for efficiently fine-tuning large language models (LLMs), with its effectiveness influenced by two key factors: rank selection and weight initialization. While numerous LoRA variants have been…

Machine Learning · Computer Science 2025-10-27 Haonan He , Peng Ye , Yuchen Ren , Yuan Yuan , Luyang Zhou , Shucun Ju , Lei Chen

Readout errors are a significant source of noise for near term quantum computers. A variety of methods have been proposed to mitigate these errors using classical post processing. For a system with $n$ qubits, the entire readout error…

Quantum Physics · Physics 2021-04-13 Benjamin Nachman , Michael R. Geller

Low Rank Decomposition of matrix - splitting a large matrix into a product of two smaller matrix offers a means for compression that reduces the parameters of a model without sparsification, and hence delivering more speedup on modern…

Computation and Language · Computer Science 2023-09-26 Ayush Kaushal , Tejas Vaidhya , Irina Rish

Background: The short reads output by first- and second-generation DNA sequencing instruments cannot completely reconstruct microbial chromosomes. Therefore, most genomes have been left unfinished due to the significant resources required…

The repeat content and heterozygosity rate of a target genome are important factors in determining the feasibility of achieving a complete telomere-to-telomere assembly. The mathematical relationship between the required coverage and read…

Information Theory · Computer Science 2025-04-08 Daanish Mahajan , Chirag Jain , Navin Kashyap

In just the last decade, a multitude of bio-technologies and software pipelines have emerged to revolutionize genomics. To further their central goal, they aim to accelerate and improve the quality of de novo whole-genome assembly starting…

Genomics · Quantitative Biology 2015-06-11 Francesco Vezzi , Giuseppe Narzisi , Bud Mishra

Quantum computers have shown promise in improving algorithms in a variety of fields. The realization of these advancements is limited by the presence of noise and high error rates, which become prominent especially with increasing system…

Quantum Physics · Physics 2025-06-05 Melody Lee

In unforeseen situations, such as nuclear power plant's or civilian radiation accidents, there is a need for effective and computationally inexpensive methods to determine the expression level of a selected gene panel, allowing for rough…

Genomics · Quantitative Biology 2024-12-13 Tomasz Strzoda , Lourdes Cruz-Garcia , Mustafa Najim , Christophe Badie , Joanna Polanska

Large language models (LLMs) often lack specialized knowledge for complex bioinformatics applications. We present a reproducible pipeline for fine-tuning LLMs on specialized bioinformatics data, demonstrated through two use cases: PRSGPT,…

Computation and Language · Computer Science 2026-01-21 Muhammad Muneeb , David B. Ascher

Recent GPU generations deliver significantly higher FLOPs using lower-precision arithmetic, such as FP8. While successfully applied to large language models (LLMs), its adoption in large recommendation models (LRMs) has been limited. This…

Existing deep learning-based depth completion methods generally employ massive stacked layers to predict the dense depth map from sparse input data. Although such approaches greatly advance this task, their accompanied huge computational…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Yufei Wang , Bo Li , Ge Zhang , Qi Liu , Tao Gao , Yuchao Dai

Nanopore sequencing, superior to other sequencing technologies for DNA storage in multiple aspects, has recently attracted considerable attention. Its high error rates, however, demand thorough research on practical and efficient coding…

Information Theory · Computer Science 2024-06-21 Anisha Banerjee , Yonatan Yehezkeally , Antonia Wachter-Zeh , Eitan Yaakobi

In this paper, we address the lifelong sequential behavior incomprehension problem in large language models (LLMs) for recommendation, where LLMs struggle to extract useful information from long user behavior sequences, even within their…

Information Retrieval · Computer Science 2025-01-24 Rong Shan , Jiachen Zhu , Jianghao Lin , Chenxu Zhu , Bo Chen , Ruiming Tang , Yong Yu , Weinan Zhang
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