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To enhance Large Language Models' (LLMs) reliability, calibration is essential -- the model's assessed confidence scores should align with the actual likelihood of its responses being correct. However, current confidence elicitation methods…
De Bruijn graph is one of the most important data structures used in de-novo genome assembly algorithms, especially for NGS data. There is a growing need for parallel data structures and algorithms due to the increasing number of cores in…
Low-Rank Adaptation (LoRA) has emerged as a widely adopted technique in text-to-image models, enabling precise rendering of multiple distinct elements, such as characters and styles, in multi-concept image generation. However, current…
Iterating with new and improved OCR solutions enforces decision making when it comes to targeting the right candidates for reprocessing. This especially applies when the underlying data collection is of considerable size and rather diverse…
Automated labeling of chest X-ray reports is essential for enabling downstream tasks such as training image-based diagnostic models, population health studies, and clinical decision support. However, the high variability, complexity, and…
Owing to its several merits over other DNA sequencing technologies, nanopore sequencers hold an immense potential to revolutionize the efficiency of DNA storage systems. However, their higher error rates necessitate further research to…
The formal version of our work has been published in BMC Bioinformatics and can be found here: http://www.biomedcentral.com/1471-2105/13/S6/S1 Motivation: To tackle the problem of huge memory usage associated with de Bruijn graph-based…
Low-Rank Adaptation (LoRA) is a crucial method for efficiently fine-tuning large language models (LLMs), with its effectiveness influenced by two key factors: rank selection and weight initialization. While numerous LoRA variants have been…
Readout errors are a significant source of noise for near term quantum computers. A variety of methods have been proposed to mitigate these errors using classical post processing. For a system with $n$ qubits, the entire readout error…
Low Rank Decomposition of matrix - splitting a large matrix into a product of two smaller matrix offers a means for compression that reduces the parameters of a model without sparsification, and hence delivering more speedup on modern…
Background: The short reads output by first- and second-generation DNA sequencing instruments cannot completely reconstruct microbial chromosomes. Therefore, most genomes have been left unfinished due to the significant resources required…
The repeat content and heterozygosity rate of a target genome are important factors in determining the feasibility of achieving a complete telomere-to-telomere assembly. The mathematical relationship between the required coverage and read…
In just the last decade, a multitude of bio-technologies and software pipelines have emerged to revolutionize genomics. To further their central goal, they aim to accelerate and improve the quality of de novo whole-genome assembly starting…
Quantum computers have shown promise in improving algorithms in a variety of fields. The realization of these advancements is limited by the presence of noise and high error rates, which become prominent especially with increasing system…
In unforeseen situations, such as nuclear power plant's or civilian radiation accidents, there is a need for effective and computationally inexpensive methods to determine the expression level of a selected gene panel, allowing for rough…
Large language models (LLMs) often lack specialized knowledge for complex bioinformatics applications. We present a reproducible pipeline for fine-tuning LLMs on specialized bioinformatics data, demonstrated through two use cases: PRSGPT,…
Recent GPU generations deliver significantly higher FLOPs using lower-precision arithmetic, such as FP8. While successfully applied to large language models (LLMs), its adoption in large recommendation models (LRMs) has been limited. This…
Existing deep learning-based depth completion methods generally employ massive stacked layers to predict the dense depth map from sparse input data. Although such approaches greatly advance this task, their accompanied huge computational…
Nanopore sequencing, superior to other sequencing technologies for DNA storage in multiple aspects, has recently attracted considerable attention. Its high error rates, however, demand thorough research on practical and efficient coding…
In this paper, we address the lifelong sequential behavior incomprehension problem in large language models (LLMs) for recommendation, where LLMs struggle to extract useful information from long user behavior sequences, even within their…