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Network meta-analysis of diagnostic test accuracy (NMA-DTA) is a relatively new field, involving combining evidence across studies to evaluate and compare the accuracy of different tests for a given condition. However, the methods proposed…

Methodology · Statistics 2026-04-23 Efthymia Derezea , Gabriel Rogers , Nicky J Welton , Hayley E Jones

Network meta-analysis (NMA) is widely used to compare multiple interventions simultaneously by synthesizing direct and indirect evidence. The general fixed or random effects contrast-based NMA model can be applied to different outcomes and…

Methodology · Statistics 2026-03-03 Harlan Campbell , Jeroen P. Jansen

Network meta-analysis (NMA) is a technique used in medical statistics to combine evidence from multiple medical trials. NMA defines an inference and information processing problem on a network of treatment options and trials connecting the…

Statistical Mechanics · Physics 2022-11-30 Annabel L. Davies , Tobias Galla

Component network meta-analysis (CNMA) models are an extension of standard network meta-analysis (NMA) models which account for the use of multicomponent treatments in the network. This article contributes innovatively to several…

Methodology · Statistics 2025-07-23 Augustine Wigle , Audrey Béliveau

Network meta-analysis (NMA) combines direct and indirect comparisons across a connected treatment network to estimate relative treatment effects. However, there is a lack of exact contribution decompositions that reproduce NMA estimates,…

Methodology · Statistics 2026-04-27 Chong Wang , Yanqi Zhang , Zhezhen Jin , Annette O'Connor

Network meta-analysis (NMA) combines evidence from multiple trials to compare the effectiveness of a set of interventions. In public health research, interventions are often complex, made up of multiple components or features. This makes it…

Methodology · Statistics 2024-01-04 Annabel L Davies , Julian P T Higgins

Network meta-analysis (NMA) is widely used in evidence synthesis to estimate the effects of several competing interventions for a given clinical condition. One of the challenges is that it is not possible in disconnected networks. Component…

Methodology · Statistics 2022-05-24 Maria Petropoulou , Gerta Rücker , Stephanie Weibel , Peter Kranke , Guido Schwarzer

Network meta-analysis (NMA) is a statistical technique for the comparison of treatment options. The nodes of the network are the competing treatments and edges represent comparisons of treatments in trials. Outcomes of Bayesian NMA include…

Methodology · Statistics 2024-01-04 Annabel L Davies , Tobias Galla

Network meta-analysis (NMA) is widely used in healthcare decision-making, where estimates of the effect of multiple treatments on outcomes are required. For time-to-event outcomes such as survival or disease progression the most common…

Methodology · Statistics 2025-09-15 David M. Phillippo , Ayman Sadek , Hugo Pedder , Nicky J. Welton

Network meta-analysis (NMA) is a useful tool to compare multiple interventions simultaneously in a single meta-analysis, it can be very helpful for medical decision making when the study aims to find the best therapy among several active…

Methodology · Statistics 2024-02-02 Ao Huang , Yi Zhou , Satoshi Hattori

Component network meta-analysis (CNMA) is a statistical methodology that enables estimation of relative effects for multi-component treatments, such as combinations of antidepressants, and individual components, such as single…

Methodology · Statistics 2026-05-15 Augustine Wigle , Audrey Béliveau , Adriani Nikolakopoulou , Lifeng Lin

There has been a transition from broad to more specific research questions in the practice of network meta-analysis (NMA). Such convergence is also taking place in the context of individual registrational trials, following the recent…

Applications · Statistics 2026-05-07 Antonio Remiro-Azócar , Anders Gorst-Rasmussen

The vulnerability of deep neural networks to adversarial examples has motivated an increasing number of defense strategies for promoting model robustness. However, the progress is usually hampered by insufficient robustness evaluations. As…

Machine Learning · Computer Science 2021-10-19 Xiao Yang , Yinpeng Dong , Wenzhao Xiang , Tianyu Pang , Hang Su , Jun Zhu

In network meta-analysis (NMA), we synthesize all relevant evidence about health outcomes with competing treatments. The evidence may come from randomized controlled trials (RCT) or non-randomized studies (NRS) as individual participant…

Network Meta-Analysis (NMA) is an increasingly popular evidence synthesis tool that can provide a ranking of competing treatments, also known as a treatment hierarchy. Treatment-Covariate Interactions (TCIs) can be included in NMA models to…

Methodology · Statistics 2026-05-13 Augustine Wigle , Erica E. M. Moodie

Explicit modelling of between-study heterogeneity is essential in network meta-analysis (NMA) to ensure valid inference and avoid overstating precision. While the additive random-effects (RE) model is the conventional approach, the…

Methodology · Statistics 2026-01-21 Xinlei Xu , Caitlin H Daly , Audrey Béliveau

Diagnosis of hematological malignancies depends on accurate identification of white blood cells in peripheral blood smears. Deep learning techniques are emerging as a viable solution to scale and optimize this process by automatic cell…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Michael Deutges , Ario Sadafi , Nassir Navab , Carsten Marr

Studies show that Studies that cardiovascular diseases (CVDs) are malignant for human health. Thus, it is important to have an efficient way of CVD prognosis. In response to this, the healthcare industry has adopted machine learning-based…

Machine Learning · Computer Science 2022-08-02 Mohammed Nowshad Ruhani Chowdhury , Wandong Zhang , Thangarajah Akilan

In recent years, there has been growing research interest in addressing treatment hierarchy questions within network meta-analysis (NMA). In NMAs involving many treatments, the number of possible hierarchy questions becomes prohibitively…

Methodology · Statistics 2025-10-13 Caitlin H. Daly , Chloe Tan , Audrey Béliveau

Network meta-analysis (NMA) of rare events has attracted little attention in the literature. Until recently, networks of interventions with rare events were analyzed using the inverse-variance NMA approach. However, when events are rare the…

Methodology · Statistics 2021-09-22 Theodoros Evrenoglou , Ian White , Sivem Afach , Dimitris Mavridis , Anna Chaimani
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