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We propose a mathematical model for estimating biological damage caused by low-dose irradiation. We understand that the Linear Non Threshold (LNT) hypothesis is realized only in the case of no recovery effects. In order to treat the…

Biological Physics · Physics 2012-10-08 Yuichiro Manabe , Kento Ichikawa , Masako Bando

The status of relativistic nuclear many-body calculations of nuclear systems to be built up in terms of protons and neutrons is reviewed. In detail, relativistic effects on several aspects of nuclear matter such as the effective mass,…

Nuclear Theory · Physics 2015-03-13 E. N. E. van Dalen , H. Müther

In the space environment, instruments onboard of spacecrafts can be affected by displacement damage due to radiation. The differential scattering cross section for screened nucleus--nucleus interactions - i.e., including the effects due to…

This paper deals with the classic radiotherapy dose fractionation problem for cancer tumors concerning the following goals: a) To maximize the effect of radiation on the tumor, restricting the effect produced to the organs at risk (healing…

Optimization and Control · Mathematics 2021-02-17 Luis Alberto Fernández , Lucía Fernández

Radiotherapy is an integral part of treatment for many patients with breast cancer. However, side effects can occur, Example fibrosis or erythema. If patients at higher risks of radiation induced side effects could be identified before…

Medical Physics · Physics 2024-09-04 Deborah E. M. Akuoko , Eliana Vasquez Osorio , Marcel Van Herk , Marianne Aznar

Although the survival rate of cancer patients has significantly increased due to advances in anti-cancer therapeutics, one of the major side effects of these therapies, particularly radiotherapy, is the potential manifestation of…

Quantitative Methods · Quantitative Biology 2014-11-07 Kamran Kaveh , Venkata S. K. Manem , Mohammad Kohandel , Siv Sivaloganathan

We propose a multi-scale approach to understanding physics related to the ion/proton-beam cancer therapy and calculation of the probability of the DNA damage as a result of irradiation of patients with energetic (up to 430 MeV/u) ions. This…

Biological Physics · Physics 2009-11-13 A. V. Solov'yov , E. Surdutovich , E. Scifoni , I. Mishustin , W. Greiner

The normal tissue complication probability (NTCP) is a measure for the estimated side effects of a given radiation treatment schedule. Here we use a stochastic logistic birth death process to define an organ specific and patient specific…

Tissues and Organs · Quantitative Biology 2014-12-11 Theresa Stocks , Thomas Hillen , Jiafen Gong , Martin Burger

We consider theoretically ionization of an atom by neutrino impact taking into account electromagnetic interactions predicted for massive neutrinos by theories beyond the Standard Model. The effects of atomic recoil in this process are…

High Energy Physics - Phenomenology · Physics 2014-12-23 Konstantin A. Kouzakov , Alexander I. Studenikin

The information about sizes and nuclear density distributions in unstable (radioactive) nuclei is usually extracted from the data on interaction of radioactive nuclear beams with a nuclear target. We show that in the case of nucleus-nucleus…

Nuclear Theory · Physics 2011-01-26 C. Merino , I. S. Novikov , Yu. M. Shabelski

In oncology, treating cancer with a beam of photons is a well established therapeutic technique, developed over 100 years, and today over 50% of cancer patients will undergo traditional X-ray radiotherapy. However, ionizing radiation…

Medical Physics · Physics 2016-02-08 Mersini Makropoulou

FLASH radiotherapy (FLASH-RT) is a new modality of radiotherapy by delivering doses with ultra-high dose rates. FLASH-RT has the ability to suppress tumor growth while sparing normal tissues, known as the FLASH effect. Although FLASH effect…

Electromagnetic radiation (photons) or particle beam (protons or heavy ions) have similar biological effects, i.e. damage to human cell DNA that eventually leads to cell death if not correctly repaired. The biological effects at the level…

Medical Physics · Physics 2018-04-24 Pierre Scalliet , John Gueulette

The treatment of the electron-nucleus interaction based on the Mott differential cross section was extended to account for effects due to screened Coulomb potentials, finite sizes and finite rest masses of nuclei for electrons above 200 keV…

Correlation between the rms nucleus charge radius and their deformation, isospin asymmetry, mass and charge numbers are presented. Four parameters radius parametrization formula is proposed. Ratio of experimental to theoretical value…

Nuclear Theory · Physics 2007-05-23 Z. Sosin

The investigation of the effects of average atomic ionization on nuclear reactions is of prime importance for nuclear astrophysics. No direct experimental measurement using a plasma target has been done yet. In this regard, we measured for…

The substantial effect of air pollution on cardiovascular disease and mortality burdens is well-established. Emissions-reducing interventions on coal-fired power plants -- a major source of hazardous air pollution -- have proven to be an…

Machine Learning · Computer Science 2025-08-19 Raphael C. Kim , Falco J. Bargagli-Stoffi , Kevin L. Chen , Rachel C. Nethery

We present new results on the ionization by electron impacts in a dense plasma. We are interested in the density effect known as the ionization potential depression and in its role in atomic structure. Rather than using the well-known…

Atomic Physics · Physics 2023-09-14 Djamel Benredjem , Jean-Christophe Pain , Annette Calisti , Sandrine Ferri

We employ a multi-scale mechanistic approach to investigate radiation induced cell toxicities and deactivation mechanisms as a function of linear energy transfer in hadron therapy. Our theoretical model consists of a system of Markov chains…

Medical Physics · Physics 2019-05-01 Ramin Abolfath , Yusuf Helo , Lawrence Bronk , Alejandro Carabe , David Grosshans , Radhe Mohan

We study $N$-electron atoms with nuclear charge $Z$. It is well known that, in the cationic ($Z > N$) high-$Z$ region, the atom behaves as a weakly interacting system. The anionic ($Z < N$) regime, on the other hand, is characterized by an…

Atomic Physics · Physics 2017-10-20 G. Gil , A. Gonzalez
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