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Predicting the secondary structure of RNA is a core challenge in computational biology, essential for understanding molecular function and designing novel therapeutics. The field has evolved from foundational but accuracy-limited…

Biomolecules · Quantitative Biology 2026-05-20 Giuseppe Sacco , Giovanni Bussi , Guido Sanguinetti

Deep Neural Networks (DNN) represent a performance-hungry application. Floating-Point (FP) and custom floating-point-like arithmetic satisfies this hunger. While there is need for speed, inference in DNNs does not seem to have any need for…

Machine Learning · Computer Science 2020-02-11 Christoph Lauter , Anastasia Volkova

Multitarget Tracking (MTT) is the problem of tracking the states of an unknown number of objects using noisy measurements, with important applications to autonomous driving, surveillance, robotics, and others. In the model-based Bayesian…

Machine Learning · Computer Science 2021-06-07 Juliano Pinto , Georg Hess , William Ljungbergh , Yuxuan Xia , Lennart Svensson , Henk Wymeersch

Structural prediction has long been considered critical in RNA research, especially following the success of AlphaFold2 in protein studies, which has drawn significant attention to the field. While recent advances in machine learning and…

Biomolecules · Quantitative Biology 2024-09-26 Jiaxing Yang

This paper introduces deep neural networks (DNNs) as add-on blocks to baseline feedback control systems to enhance tracking performance of arbitrary desired trajectories. The DNNs are trained to adapt the reference signals to the feedback…

Robotics · Computer Science 2017-10-09 Siqi Zhou , Mohamed K. Helwa , Angela P. Schoellig

Imagine experiencing a crash as the passenger of an autonomous vehicle. Wouldn't you want to know why it happened? Current end-to-end optimizable deep neural networks (DNNs) in 3D detection, multi-object tracking, and motion forecasting…

Computer Vision and Pattern Recognition · Computer Science 2022-10-05 Benjamin Thérien , Krzysztof Czarnecki

Learning sophisticated feature interactions behind user behaviors is critical in maximizing CTR for recommender systems. Despite great progress, existing methods seem to have a strong bias towards low- or high-order interactions, or require…

Information Retrieval · Computer Science 2017-03-14 Huifeng Guo , Ruiming Tang , Yunming Ye , Zhenguo Li , Xiuqiang He

Despite a lack of theoretical understanding, deep neural networks have achieved unparalleled performance in a wide range of applications. On the other hand, shallow representation learning with component analysis is associated with rich…

Machine Learning · Computer Science 2018-03-20 Calvin Murdock , Ming-Fang Chang , Simon Lucey

Capturing audio signals with specific directivity patterns is essential in speech communication. This study presents a deep neural network (DNN)-based approach to directional filtering, alleviating the need for explicit signal models. More…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-23 Julian Wechsler , Srikanth Raj Chetupalli , Mhd Modar Halimeh , Oliver Thiergart , Emanuël A. P. Habets

Deep neural networks are learning models with a very high capacity and therefore prone to over-fitting. Many regularization techniques such as Dropout, DropConnect, and weight decay all attempt to solve the problem of over-fitting by…

Machine Learning · Computer Science 2016-12-06 Armen Aghajanyan

The choice of learning rate (LR) functions and policies has evolved from a simple fixed LR to the decaying LR and the cyclic LR, aiming to improve the accuracy and reduce the training time of Deep Neural Networks (DNNs). This paper presents…

Machine Learning · Computer Science 2022-10-25 Yanzhao Wu , Ling Liu

The first step in drug discovery is finding drug molecule moieties with medicinal activity against specific targets. Therefore, it is crucial to investigate the interaction between drug-target proteins and small chemical molecules. However,…

Biomolecules · Quantitative Biology 2022-11-15 Boyuan Liu

The accurate tracking of live cells using video microscopy recordings remains a challenging task for popular state-of-the-art image processing based object tracking methods. In recent years, several existing and new applications have…

Image and Video Processing · Electrical Eng. & Systems 2025-02-03 Gergely Szabó , Paolo Bonaiuti , Andrea Ciliberto , András Horváth

In an ever expanding set of research and application areas, deep neural networks (DNNs) set the bar for algorithm performance. However, depending upon additional constraints such as processing power and execution time limits, or…

Machine Learning · Computer Science 2021-06-22 Nathan Dahlin , Krishna Chaitanya Kalagarla , Nikhil Naik , Rahul Jain , Pierluigi Nuzzo

Hypernetworks, or hypernets for short, are neural networks that generate weights for another neural network, known as the target network. They have emerged as a powerful deep learning technique that allows for greater flexibility,…

Machine Learning · Computer Science 2025-01-03 Vinod Kumar Chauhan , Jiandong Zhou , Ping Lu , Soheila Molaei , David A. Clifton

The tracking-by-detection framework requires a set of positive and negative training samples to learn robust tracking models for precise localization of target objects. However, existing tracking models mostly treat different samples…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Xiao Wang , Chenglong Li , Rui Yang , Tianzhu Zhang , Jin Tang , Bin Luo

We propose a novel training method that integrates rules into deep learning, in a way the strengths of the rules are controllable at inference. Deep Neural Networks with Controllable Rule Representations (DeepCTRL) incorporates a rule…

Machine Learning · Computer Science 2021-11-18 Sungyong Seo , Sercan O. Arik , Jinsung Yoon , Xiang Zhang , Kihyuk Sohn , Tomas Pfister

The neuron reconstruction from raw Optical Microscopy (OM) image stacks is the basis of neuroscience. Manual annotation and semi-automatic neuron tracing algorithms are time-consuming and inefficient. Existing deep learning neuron…

Computer Vision and Pattern Recognition · Computer Science 2022-12-09 Yijun Wang , Rui Lang , Rui Li , Junsong Zhang

Should we input known genome sequence features or input sequence itself in deep learning framework? As deep learning more popular in various applications, researchers often come to question whether to generate features or use raw sequences…

Machine Learning · Computer Science 2017-10-19 Jaya Thomas , Sonia Thomas , Lee Sael

In many real-life tasks of application of supervised learning approaches, all the training data are not available at the same time. The examples are lifelong image classification or recognition of environmental objects during interaction of…

Machine Learning · Computer Science 2020-06-15 Miltiadis Poursanidis , Jenny Benois-Pineau , Akka Zemmari , Boris Mansenca , Aymar de Rugy
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