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The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Luciano da Fontoura Costa , Regina Celia Coelho

We study scaling limits of non-increasing Markov chains with values in the set of non-negative integers, under the assumption that the large jump events are rare and happen at rates that behave like a negative power of the current state. We…

Probability · Mathematics 2012-01-06 Bénédicte Haas , Grégory Miermont

In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…

Analysis of PDEs · Mathematics 2021-08-31 Xu'an Dou , Jian-Guo Liu , Zhennan Zhou

We study a class of Markovian systems of $N$ elements taking values in $[0,1]$ that evolve in discrete time $t$ via randomized replacement rules based on the ranks of the elements. These rank-driven processes are inspired by variants of the…

Probability · Mathematics 2012-01-06 Michael Grinfeld , Philip A. Knight , Andrew R. Wade

We study the dynamics of proliferating cell collectives whose microscopic constituents' growth is inhibited by macroscopic growth-induced stress. Discrete particle simulations of a growing collective show the emergence of concentric-ring…

Biological Physics · Physics 2024-05-17 Scott Weady , Bryce Palmer , Adam Lamson , Taeyoon Kim , Reza Farhadifar , Michael J. Shelley

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

Probability · Mathematics 2022-04-27 Nam H Nguyen , Marek Kimmel

A big challenge in current biology is to understand the exact self-organization mechanism underlying complex multi-physics coupling developmental processes. With multiscale computations of from subcellular gene expressions to cell…

Cell Behavior · Quantitative Biology 2021-05-18 Xiaoliang Wang , Dongyun Bai

Let \xi_t, t\in[0,T], be a strong Markov process with values in a complete separable metric space (X,\rho) and with transition probability function P_{s,t}(x,dy), 0\le s\le t\le T, x\in X. For any h\in[0,T] and a>0, consider the function…

Probability · Mathematics 2016-09-07 Martynas Manstavicius

We study a coarsening process of one-dimensional cell complexes. We show that if cell boundaries move with velocities proportional to the difference in size of neighboring cells, then the average cell size grows at a prescribed exponential…

Probability · Mathematics 2015-12-03 Emanuel Lazar , Robin Pemantle

We consider the fragmentation at nodes of the L\'{e}vy continuous random tree introduced in a previous paper. In this framework we compute the asymptotic for the number of small fragments at time $\theta$. This limit is increasing in…

Probability · Mathematics 2007-05-23 Romain Abraham , Jean-François Delmas

Similarly as in (Blancas et al. 2018) where nested coalescent processes are studied, we generalize the definition of partition-valued homogeneous Markov fragmentation processes to the setting of nested partitions, i.e. pairs of partitions…

Probability · Mathematics 2018-07-17 Jean-Jil Duchamps

Stem cells, through their ability to produce daughter stem cells and differentiate into specialized cells, are essential in the growth, maintenance, and repair of biological tissues. Understanding the dynamics of cell populations in the…

Applications · Statistics 2026-02-02 Huyen Nguyen , Haim Bar , Zhiyi Chi , Vladimir Pozdnyakov

Many biological processes and objects can be described by fractals. The paper uses a new type of objects - blinking fractals - that are not covered by traditional theories considering dynamics of self-similarity processes. It is shown that…

Chaotic Dynamics · Physics 2012-03-15 Yaroslav D. Sergeyev

Can we obtain a Brownian CRT of mass $1/2$ from a CRT of mass $1$ by cutting certain branches? In this paper, we will answer that question in the much more general setting of self-similar Markov trees. Self-similar Markov trees (ssMt) are…

Probability · Mathematics 2025-12-19 Nicolas Curien , William Fleurat , Adrianus Twigt

Boundary-catalytic branching processes describe a broad class of natural phenomena where the population of diffusing particles grows due to their spontaneous binary branching (e.g., division, fission or splitting) on a catalytic boundary…

Statistical Mechanics · Physics 2026-03-05 Denis S. Grebenkov , Yilin Ye

An explicit solution for a general two-type birth-death branching process with one way mutation is presented. This continuous time process mimics the evolution of resistance to treatment, or the onset of an extra driver mutation during…

Populations and Evolution · Quantitative Biology 2012-04-20 Tibor Antal , P. L. Krapivsky

A recent burst of dynamic single-cell growth-division data makes it possible to characterize the stochastic dynamics of cell division control in bacteria. Different modeling frameworks were used to infer specific mechanisms from such data,…

Cell Behavior · Quantitative Biology 2017-03-22 Jacopo Grilli , Matteo Osella , Andrew S. Kennard , Marco Cosentino Lagomarsino

Spatial birth-and-death processes with time dependent rates are obtained as solutions to certain stochastic equations. The existence, uniqueness, uniqueness in law and the strong Markov property of unique solutions are proven when the…

Probability · Mathematics 2022-04-22 Viktor Bezborodov , Luca Di Persio

Metastasis represents one of the main clinical challenge in cancer treatment since it is associated with the majority of deaths. Recent technological advances allow quantification of the dynamics of the process by means of noninvasive…

Tissues and Organs · Quantitative Biology 2015-11-06 Sébastien Benzekry , J. M. L. Ebos

A Markov evolution of a system of point particles in $\mathbb{R}^d$ is described at micro-and mesoscopic levels. The particles reproduce themselves at distant points (dispersal) and die, independently and under the influence of each other…

Mathematical Physics · Physics 2015-06-11 Dmitri Finkelshtein , Yuri Kondratiev , Yuri Kozitsky , Oleksandr Kutoviy