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Related papers: Quantifying topological invariants of neuronal mor…

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Neuronal morphology encodes critical information about circuit function, development, and disease, yet current methods analyze topology or graph structure in isolation. We introduce GraPHFormer, a multimodal architecture that unifies these…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Uzair Shah , Marco Agus , Mahmoud Gamal , Mahmood Alzubaidi , Corrado Cali , Pierre J. Magistretti , Abdesselam Bouzerdoum , Mowafa Househ

We use Topological Data Analysis tools for studying the inner organization of cells in segmented images of epithelial tissues. More specifically, for each segmented image, we compute different persistence barcodes, which codify lifetime of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-11 N. Atienza , M. J. Jimenez , M. Soriano-Trigueros

The structural analysis of shape boundaries leads to the characterization of objects as well as to the understanding of shape properties. The literature on graphs and networks have contributed to the structural characterization of shapes…

Computer Vision and Pattern Recognition · Computer Science 2017-11-15 Gisele H. B. Miranda , Jeaneth Machicao , Odemir M. Bruno

Various structures in human physiology follow a treelike morphology, which often expresses complexity at very fine scales. Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels. Large…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Hao Li , Zeyu Tang , Yang Nan , Guang Yang

This work presents a procedure to extract morphological information from neuronal cells based on the variation of shape functionals as the cell geometry undergoes a dilation through a wide interval of spatial scales. The targeted shapes are…

Understanding the response of an output variable to multi-dimensional inputs lies at the heart of many data exploration endeavours. Topology-based methods, in particular Morse theory and persistent homology, provide a useful framework for…

Graphics · Computer Science 2022-08-16 Yarden Livnat , Dan Maljovec , Attila Gyulassy , Dr Baptiste Mouginot , Valerio Pascucci

The complexity of a neuronal cell shape is known to be related to its function. Specifically, among other indicators, a decreased complexity in the dendritic trees of cortical pyramidal neurons has been associated with mental retardation.…

Quantitative Methods · Quantitative Biology 2007-05-23 M. S. Barbosa , L. da F. Costa , E. S. Bernardes , G. Ramakers , J. van Pelt

The statistical mechanical approach to complex networks is the dominant paradigm in describing natural and societal complex systems. The study of network properties, and their implications on dynamical processes, mostly focus on locally…

Statistical Mechanics · Physics 2013-06-27 Giovanni Petri , Martina Scolamiero , Irene Donato , Francesco Vaccarino

Although neural networks are capable of reaching astonishing performances on a wide variety of contexts, properly training networks on complicated tasks requires expertise and can be expensive from a computational perspective. In industrial…

Machine Learning · Statistics 2021-05-11 Théo Lacombe , Yuichi Ike , Mathieu Carriere , Frédéric Chazal , Marc Glisse , Yuhei Umeda

A central question for neuroscience is how to characterize brain representations of perceptual and cognitive content. An ideal characterization should distinguish different functional regions with robustness to noise and idiosyncrasies of…

Neurons and Cognition · Quantitative Biology 2024-10-17 Baihan Lin , Nikolaus Kriegeskorte

This is a survey article on trees, with a modest number of proofs to give a flavor of the way these topologies can be efficiently handled. Trees are defined in set-theorist fashion as partially ordered sets in which the elements below each…

General Topology · Mathematics 2007-05-23 Peter J. Nyikos

The human brain cortical layer has a convoluted morphology that is unique to each individual. Characterization of the cortical morphology is necessary in longitudinal studies of structural brain change, as well as in discriminating…

Neurons and Cognition · Quantitative Biology 2019-02-21 Sevil Maghsadhagh , Anders Eklund , Hamid Behjat

Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

Neurons and Cognition · Quantitative Biology 2024-02-28 Jiachen Yao , Nina Hagemann , Qiaojie Xiong , Jianxu Chen , Dirk M. Hermann , Chao Chen

We prove that for a broad class of permutation-equivariant learning rules (including SGD, Adam, and others), the training process induces a bi-Lipschitz mapping between neurons and strongly constrains the topology of the neuron distribution…

Machine Learning · Computer Science 2025-10-06 Yongyi Yang , Tomaso Poggio , Isaac Chuang , Liu Ziyin

Geometric trees are characterized by their tree-structured layout and spatially constrained nodes and edges, which significantly impacts their topological attributes. This inherent hierarchical structure plays a crucial role in domains such…

Machine Learning · Computer Science 2024-08-19 Zheng Zhang , Allen Zhang , Ruth Nelson , Giorgio Ascoli , Liang Zhao

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Comparing weighted networks in neuroscience is hard, because the topological properties of a given network are necessarily dependent on the number of edges of that network. This problem arises in the analysis of both weighted and unweighted…

Applications · Statistics 2014-03-28 Cedric E. Ginestet , Arnaud P. Fournel , Andrew Simmons

Revealing the structural features of a complex system from the observed collective dynamics is a fundamental problem in network science. In order to compute the various topological descriptors commonly used to characterize the structure of…

Data Analysis, Statistics and Probability · Physics 2021-02-16 Sebastian Raimondo , Manlio De Domenico

Classification of biological neuron types and networks poses challenges to the full understanding of the brain's organisation and functioning. In this paper, we develop a novel objective classification model of biological neuronal types and…

Neurons and Cognition · Quantitative Biology 2020-03-31 Michael Taynnan Barros , Harun Siljak , Peter Mullen , Constantinos Papadias , Jari Hyttinen , Nicola Marchetti

Understanding generalization and robustness of machine learning models fundamentally relies on assuming an appropriate metric on the data space. Identifying such a metric is particularly challenging for non-Euclidean data such as graphs.…

Machine Learning · Computer Science 2022-10-06 Ching-Yao Chuang , Stefanie Jegelka