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Optical imaging deep inside scattering media remains a fundamental problem in bio-imaging. While wavefront shaping has been shown to allow focusing of coherent light at depth, achieving it non-invasively remains a challenge. Various…

Optics · Physics 2019-12-24 Antoine Boniface , Baptiste Blochet , Jonathan Dong , Sylvain Gigan

Light-based synthetic aperture (SA) imaging methods, such as Fourier Ptychography, have brought breakthrough high-resolution wide-field-of-view imaging capabilities to microscopy. While these technologies promise similar improvements in…

Optics · Physics 2025-09-29 Janith B. Senanayaka , Christopher A. Metzler

Phase retrieval in inline holography is a fundamental yet ill-posed inverse problem due to the nonlinear coupling between amplitude and phase in coherent imaging. We present a novel off-the-shelf solution that leverages a diffusion model…

Optics · Physics 2025-11-12 Jeongsol Kim , Chanseok Lee , Jongin You , Jong Chul Ye , Mooseok Jang

Current single-molecule imaging techniques are incapable of providing stochastic information of individual chemical reactions. We have developed an optical imaging method for stochastic analysis of individual electrochemical reactions. The…

Optics · Physics 2023-05-22 Wei Liu , Meng Li , Houqiang Teng , Heshan Liu , Zhi Li , Yu Niu , Ziren Luo

Complementary to conventional and phase X-ray radiography, dark-field imaging has become central in visualizing diffusive scattering signal due to the spatially-unresolved texture within an object. To date most diffusive-dark-field…

Medical Physics · Physics 2023-03-21 Mario A. Beltran , David M. Paganin , Michelle K. Croughan , Kaye S. Morgan

Light scattering in inhomogeneous media induces wavefront distortions which pose an inherent limitation in many optical applications. Examples range from microscopy and nanosurgery to astronomy. In recent years, ongoing efforts have made…

Optics · Physics 2015-05-20 Ori Katz , Yaron Bromberg , Eran Small , Yaron Silberberg

Far-field super-resolution fluorescence microscopy has been rapidly developed for applications ranging from cell biology to nanomaterials. However, it remains a significant challenge to achieve super-resolution imaging at depth in opaque…

Optics · Physics 2024-05-01 Tengfei Wu , YoonSeok Baek , Fei Xia , Sylvain Gigan , Hilton B. de Aguiar

Holography is 3D imaging which can record intensity and phase at the same time. The importance of construct hologram is holographic recording and wavefront reconstruction. It is surprised that holography be discovered in study interstellar…

Astrophysics · Physics 2009-11-02 Jiang Dong

Modern imaging techniques at the molecular scale rely on utilizing novel coherent light sources like X-ray free electron lasers for the ultimate goal of visualizing such objects as individual biomolecules rather than crystals. Here, unlike…

X-ray dark-field imaging visualises scattering from sample microstructure, and has found application in medical and security contexts. While most X-ray dark-field imaging techniques rely on masks, gratings, or crystals, recent work on the…

We describe a self calibrating optical technique that allows to perform absolute measurements of scattering cross sections for the light scattered at extremely small angles. Very good performances are obtained by using a very simple optical…

Optics · Physics 2009-11-10 Doriano Brogioli , Alberto Vailati , Marzio Giglio

Digital holography numerically restores three-dimensional image information using optically captured diffractive waves. The required bandwidth is larger than that of hologram pixel at a closer distance in the Fresnel diffraction regime,…

Optics · Physics 2024-01-12 Byung Gyu Chae

Using optical speckle scanning microscopy [1], we demonstrate that clear images of multiple cells can be obtained through biological scattering tissue, with subcellular resolution and good image quality, as long as the size of the imaging…

Optics · Physics 2023-07-19 Xin Yang , Ye Pu , Demetri Psaltis

This paper is concerned with the inverse scattering problem by an unbounded rough surface. A direct imaging method is proposed to reconstruct the rough surface from the scattered near-field Cauchy data generating by point sources and…

Numerical Analysis · Mathematics 2018-05-01 Xiaoli Liu , Bo Zhang , Haiwen Zhang

Many applications of short-wavelength radiation impose strong requirements on the coherence properties of the source. However, the measurement of such properties poses a challenge, mainly due to the lack of high-quality optics and source…

We demonstrate a motion-free intensity diffraction tomography technique that enables direct inversion of 3D phase and absorption from intensity-only measurements for weakly scattering samples. We derive a novel linear forward model,…

Image and Video Processing · Electrical Eng. & Systems 2018-06-26 Ruilong Ling , Waleed Tahir , Hsing-Ying Lin , Hakho Lee , Lei Tian

In turbid media, scattering of light scrambles information of the incident beam and represents an obstacle to optical imaging. Noninvasive imaging through opaque layers is challenging for dynamic and wide-field objects due to unreliable…

Optics · Physics 2018-10-17 Yuan Yuan , Hui Chen

Noninvasive optical imaging through dynamic scattering media has numerous important biomedical applications but still remains a challenging task. While standard diffuse imaging methods measure optical absorption or fluorescent emission, it…

Imaging through scattering and random media is an outstanding problem that to date has been tackled by either measuring the medium transmission matrix or exploiting linear correlations in the transmitted speckle patterns. However,…

Optics · Physics 2022-04-07 Ilya Starshynov , Alex Turpin , Philip Binner , Daniele Faccio

Optical approaches to fluorescent, spectroscopic, and morphological imaging have made exceptional advances in the last decade. Super-resolution imaging and wide-field multiphoton imaging are now underpinning major advances across the…