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Diagnosing glaucoma progression is critical for limiting irreversible vision loss. A common method for assessing glaucoma progression uses a longitudinal series of visual fields (VF) acquired at regular intervals. VF data are characterized…

Applications · Statistics 2018-05-31 Samuel I. Berchuck , Jean-Claude Mwanza , Joshua L. Warren

The Bayesian approach has become increasingly popular because it allows to model quite complex models via Markov chain Monte Carlo (MCMC) sampling. However, it is also recognized nowadays that MCMC sampling can become computationally…

Glaucoma is a major eye disease, leading to vision loss in the absence of proper medical treatment. Current diagnosis of glaucoma is performed by ophthalmologists who are often analyzing several types of medical images generated by…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Mijung Kim , Olivier Janssens , Ho-min Park , Jasper Zuallaert , Sofie Van Hoecke , Wesley De Neve

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

Medical Physics · Physics 2020-06-17 Changhee Lee , Mihaela van der Schaar

Glaucoma is a progressive optic neuropathy characterized by structural damage to the optic nerve head and functional changes in the visual field. Detecting glaucoma early is crucial to preventing loss of eyesight. However, medical datasets…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Youssof Nawar , Nouran Soliman , Moustafa Wassel , Mohamed ElHabebe , Noha Adly , Marwan Torki , Ahmed Elmassry , Islam Ahmed

The utilization of longitudinal datasets for glaucoma progression prediction offers a compelling approach to support early therapeutic interventions. Predominant methodologies in this domain have primarily focused on the direct prediction…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Zhihao Zhao , Junjie Yang , Shahrooz Faghihroohi , Yinzheng Zhao , Daniel Zapp , Kai Huang , Nassir Navab , M. Ali Nasseri

Subject of research: is the study of methods for analyzing perimetric images for the diagnosis and control of glaucoma diseases. Objects of research: is a dataset collected on the ophthalmological perimeter with the results of various…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 A. I. Medvedeva , V. V. Bakutkin

We develop a novel algorithm, Predictive Hierarchical Clustering (PHC), for agglomerative hierarchical clustering of current procedural terminology (CPT) codes. Our predictive hierarchical clustering aims to cluster subgroups, not…

Methodology · Statistics 2017-08-03 Elizabeth C. Lorenzi , Stephanie L. Brown , Zhifei Sun , Katherine Heller

Glaucoma disease progression, as measured by visual field (VF) data, is often defined by periods of relative stability followed by an abrupt decrease in visual ability at some point in time. Determining the transition point of the disease…

Applications · Statistics 2018-11-28 Samuel I. Berchuck , Jean-Claude Mwanza , Joshua L. Warren

Healthcare datasets often contain groups of highly correlated features, such as features from the same biological system. When feature selection is applied to these datasets to identify the most important features, the biases inherent in…

Machine Learning · Computer Science 2022-07-07 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

Objective: Glaucoma is the second leading cause of blindness worldwide. Glaucomatous progression can be easily monitored by analyzing the degeneration of retinal ganglion cells (RGCs). Many researchers have screened glaucoma by measuring…

Image and Video Processing · Electrical Eng. & Systems 2020-11-22 Hina Raja , Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi

Time series forecasting has gained lots of attention recently; this is because many real-world phenomena can be modeled as time series. The massive volume of data and recent advancements in the processing power of the computers enable…

Machine Learning · Computer Science 2021-04-01 Manie Tadayon , Yumi Iwashita

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly. Current grading systems based on imaging biomarkers only coarsely group disease stages into broad categories and are unable to predict future disease…

We model longitudinal macular thickness measurements to monitor the course of glaucoma and prevent vision loss due to disease progression. The macular thickness varies over a 6$\times$6 grid of locations on the retina with additional…

Applications · Statistics 2023-03-22 Erica Su , Robert E. Weiss , Kouros Nouri-Mahdavi , Andrew J. Holbrook

Glaucoma is a chronic eye disease characterized by optic neuropathy, leading to irreversible vision loss. It progresses gradually, often remaining undiagnosed until advanced stages. Early detection is crucial to monitor atrophy and develop…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Sayan Mandal

Graph-based clustering methods have demonstrated the effectiveness in various applications. Generally, existing graph-based clustering methods first construct a graph to represent the input data and then partition it to generate the…

Machine Learning · Computer Science 2019-12-17 Yuheng Jia , Hui Liu , Junhui Hou , Sam Kwong

Despite recent development in methodology, community detection remains a challenging problem. Existing literature largely focuses on the standard setting where a network is learned using an observed adjacency matrix from a single data…

Methodology · Statistics 2018-06-21 Luwan Zhang , Katherine Liao , Issac Kohane , Tianxi Cai

Glaucoma is one of the most severe eye diseases, characterized by rapid progression and leading to irreversible blindness. It is often the case that diagnostics is carried out when one's sight has already significantly degraded due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Ahmed Al Mahrooqi , Dmitrii Medvedev , Rand Muhtaseb , Mohammad Yaqub

In this paper, a novel method to perform model-based clustering of time series is proposed. The procedure relies on two iterative steps: (i) K global forecasting models are fitted via pooling by considering the series pertaining to each…

Machine Learning · Statistics 2023-05-02 Ángel López Oriona , Pablo Montero Manso , José Antonio Vilar Fernández

Clustering is a widely-used data mining tool, which aims to discover partitions of similar items in data. We introduce a new clustering paradigm, \emph{accordant clustering}, which enables the discovery of (predefined) group level insights.…

Machine Learning · Computer Science 2017-04-11 Amit Dhurandhar , Margareta Ackerman , Xiang Wang
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