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Spatial navigation in mammals is based on building a mental representation of their environment---a cognitive map. However, both the nature of this cognitive map and its underpinning in neural structures and activity remains vague. A key…

Neurons and Cognition · Quantitative Biology 2016-03-22 A. Babichev , S. Cheng , Yu. Dabaghian

The spiking activity of the hippocampal place cells plays a key role in producing and sustaining an internalized representation of the ambient space---a cognitive map. These cells do not only exhibit location-specific spiking during…

Neurons and Cognition · Quantitative Biology 2018-11-05 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian

Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic…

Neurons and Cognition · Quantitative Biology 2018-10-30 Y. Dabaghian

The spiking activity of principal cells in mammalian hippocampus encodes an internalized neuronal representation of the ambient space---a cognitive map. Once learned, such a map enables the animal to navigate a given environment for a long…

Neurons and Cognition · Quantitative Biology 2017-10-10 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian

Spatial awareness in mammals is based on internalized representations of the environment---cognitive maps---encoded by networks of spiking neurons. Although behavioral studies suggest that these maps can remain stable for long periods, it…

Neurons and Cognition · Quantitative Biology 2019-09-18 Yuri Dabaghian

It is widely accepted that the hippocampal place cells' spiking activity produces a cognitive map of space. However, many details of this representation's physiological mechanism remain unknown. For example, it is believed that the place…

Neurons and Cognition · Quantitative Biology 2015-09-08 A. Babichev , D. Ji , F. Memoli , Y. Dabaghian

Place cells in the rat hippocampus play a key role in creating the animal's internal representation of the world. During active navigation, these cells spike only in discrete locations, together encoding a map of the environment.…

Neurons and Cognition · Quantitative Biology 2016-03-22 Yuri Dabaghian

Topological data analyses are rapidly turning into key tools for quantifying large volumes of neurobiological data, e.g., for organizing the spiking outputs of large neuronal ensembles and thus gaining insights into the information produced…

Neurons and Cognition · Quantitative Biology 2019-09-18 Yuri Dabaghian

Hippocampal cognitive map---a neuronal representation of the spatial environment---is broadly discussed in the computational neuroscience literature for decades. More recent studies point out that hippocampus plays a major role in producing…

Neurons and Cognition · Quantitative Biology 2017-10-18 Andrey Babichev , Yuri Dabaghian

The proposed analysis of the currently available experimental results concerning the neural cell activity in the brain area known as hippocampus suggests a particular mechanism of spatial information and memory processing. Below it is…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Yu. Dabaghian , A. G. Cohn , L. Frank

Space is represented in the mammalian brain by the activity of hippocampal place cells as well as in their spike-timing correlations. Here we propose a theory how this temporal code is transformed to spatial firing rate patterns via…

Neurons and Cognition · Quantitative Biology 2017-08-02 Mauro M. Monsalve-Mercado , Christian Leibold

Mammalian hippocampus plays a key role in spatial learning and memory, but the exact nature of the hippocampal representation of space is still being explored. Recently, there has been a fair amount of success in modeling hippocampal…

Neurons and Cognition · Quantitative Biology 2016-01-19 Kentaro Hoffman , Andrey Babichev , Yuri Dabaghian

The hippocampal formation is thought to learn spatial maps of environments, and in many models this learning process consists of forming a sensory association for each location in the environment. This is inefficient, akin to learning a…

Artificial Intelligence · Computer Science 2021-07-02 Marcus Lewis

Oscillations are a hallmark of neural population activity in various brain regions with a spectrum covering a wide range of frequencies. Within this spectrum gamma oscillations have received particular attention due to their ubiquitous…

Neurons and Cognition · Quantitative Biology 2020-01-22 Hongjie Bi , Marco Segneri , Matteo di Volo , Alessandro Torcini

Visually induced neuronal activity in V1 displays a marked gamma-band component which is modulated by stimulus properties. It has been argued that synchronized oscillations contribute to these gamma-band activity [... however,] even when…

Neurons and Cognition · Quantitative Biology 2011-12-20 Demian Battaglia , David Hansel

We study the synchronisation of neurons in a realistic model under the Hodgkin-Huxley dynamics. To focus on the role of the different locations of the excitatory synapses, we use two identical neurons where the set of input signals is…

Neurons and Cognition · Quantitative Biology 2024-09-17 Alessandro Fiasconaro , Michele Migliore

Grid cells play a principal role in enabling mammalian cognitive representations of ambient environments. The key property of these cells -- the regular arrangement of their firing fields -- is commonly viewed as means for establishing…

Neurons and Cognition · Quantitative Biology 2022-08-30 Yuri Dabaghian

It has been hypothesized that Gamma cortical oscillations play important roles in numerous cognitive processes and may involve psychiatric conditions including anxiety, schizophrenia, and autism. Gamma rhythms are commonly observed in many…

Neurons and Cognition · Quantitative Biology 2021-03-11 Fereshteh Arab , Sareh Rostami , Mohammad Dehghani-Habibabadi , Vahid Salari , Mir-Shahram Safari

We investigate different dynamical regimes of neuronal network in the CA3 area of the hippocampus. The proposed neuronal circuit includes two fast- and two slowly-spiking cells which are interconnected by means of dynamical synapses. On the…

Neurons and Cognition · Quantitative Biology 2015-11-20 Anastasia I. Lavrova , Michael A. Zaks , Lutz Schimansky-Geier

The hippocampus is often attributed to episodic memory formation and storage in the mammalian brain; in particular, Alme et al. showed that hippocampal area CA3 forms statistically independent representations across a large number of…

Neurons and Cognition · Quantitative Biology 2021-01-01 Bhav Jain , Sean Elliott
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