Related papers: Modeling, dynamics and optimal control of Ebola vi…
We study the impact of parameter estimation and state measurement errors on a control framework for optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic…
The unexpected Ebola virus outbreak in West Africa in 2014 involving the Zaire ebolavirus made clear that other regions outside Central Africa, its previously documented niche, were at risk of future epidemics. The complex transmission…
We study a resource allocation problem for containing an infectious disease in a metapopulation subject to resource uncertainty. We propose a two-stage model where the policy maker seeks to allocate resources in both stages where the second…
Nowadays, epidemic models provide an appropriate tool for describing the propagation of biological viruses in human or animal populations, or rumours and other kinds of information in social networks and malware in both computer and ad hoc…
The 2014 epidemic of the Ebola virus is governed by a genetically diverse viral population. In the early Sierra Leone outbreak, a recent study has identified new mutations that generate genetically distinct sequence clades. Here we find…
Ebola virus disease is a lethal human and primate disease that currently requires a particular attention from the international health authorities due to important outbreaks in some Western African countries and isolated cases in the United…
We use a multivariate formulation of sequential Monte Carlo filter that utilizes mechanistic models for Ebola virus propagation and available incidence data to simultaneously estimate the disease progression states and the model parameters.…
The 2014-2015 Ebola Virus Disease (EVD) epidemic in West Africa was the largest ever recorded, representing a fundamental shift in Ebola epidemiology with unprecedented spatiotemporal complexity. We developed spatial transmission models…
This paper proposes a novel discrete-time multi-virus susceptible-infected-recovered (SIR) model that captures the spread of competing epidemics over a population network. First, we provide sufficient conditions for the infection level of…
Zoonotic diseases spread through pathogens-infected animal carriers. In the case of Ebola Virus Disease (EVD), evidence supports that the main carriers are fruit bats and non-human primates. Further, EVD spread is a multi-factorial problem…
This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…
The emergence of diseases such as Zika and Ebola has highlighted the need to understand the role of sexual transmission in the spread of diseases with a primarily non-sexual transmission route. In this paper we develop a number of…
We consider the problem of the optimal allocation of vaccination and protection measures for the Susceptible-Infected-Recovered-Infected (SIRI) epidemiological model, which generalizes the classical Susceptible-Infected-Recovered (SIR) and…
Tuberculosis (TB) is among the main public health challenges in Burundi. The literature lacks mathematical models for key parameter estimates of TB transmission dynamics in Burundi. In this paper, the supectible-exposed-infected-recovered…
This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…
Connecting the different scales of epidemic dynamics, from individuals to communities to nations, remains one of the main challenges of disease modeling. Here, we revisit one of the largest public health efforts deployed against a localized…
We propose a dynamical model for describing the spread of epidemics. This model is an extension of the SIQR (susceptible-infected-quarantined-recovered) and SIRP (susceptible-infected-recovered-pathogen) models used earlier to describe…
The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…
We consider a behavioral-feedback SIR epidemic model, in which the infection rate depends in feedback on the fractions of susceptible and infected agents, respectively. The considered model allows one to account for endogenous adaptation…
In this paper we introduce an approach to the management of infectious disease diffusion through the formulation of a controlled compartmental SVIR (Susceptible-Vaccinated-Infected-Recovered) model. We consider a cost functional…