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Cellular differentiation is governed by gene regulatory networks, the high-dimensional stochastic biochemical systems that determine the transcriptional landscape and mediate cellular responses to signals and perturbations. Although…
There is mounting evidence that lipid bilayers display conductive properties. However, when interpreting the electrical response of biological membranes to voltage changes, they are commonly considered as inert insulators. However, lipid…
The classical theory of electrokinetic phenomena assumes a dilute solution of point-like ions in chemical equilibrium with a surface whose double-layer voltage is of order the thermal voltage, $k_BT/e = 25$ mV. In nonlinear…
In a recent Letter, Gutin, Abkevich, and Shakhnovich (GAS) reported on a series of dynamical Monte Carlo simulations on lattice models of proteins. Based on these highly simplified models, they found that four different potential energies…
Atomistic simulations have been performed to investigate the effect of aliphatic chain length in tetraalkylphosphonium cations on liquid morphologies, microscopic ionic structures and dynamical properties of tetraalkylphosphonium chloride…
Non-invasive assessment of the electrical activation pattern can significantly contribute to the diagnosis and treatment of cardiac arrhythmias, due to faster and safer diagnosis, improved surgical planning and easier follow-up. One…
The energy for protein folding arises from multiple sources and is not large in total. In spite of the many specific successes of energy landscape and other approaches, there still seems to be some missing guiding factor that explains how…
Radio pulsar polarization exhibits a number of complex phenomena that are classified into the realm of `beyond the rotating vector model' (RVM). It is shown that these effects can be understood in geometrical terms, as a result of coherent…
We consider the spatially homogeneous Boltzmann equation for (true) hard and moderately soft potentials. We study the pathwise properties of the stochastic process $(V_t)_{t\geq 0}$, which describes the time evolution of the velocity of a…
Metastases are the primary cause of death in cancer patients. Small animal models are helping in dissecting some of key features in the metastatic cascade. Yet, tools for systematically analyze the contribution of blood flow, vascular…
Traditional stochastic modeling of reactive systems limits the domain of applicability of the associated path thermodynamics to systems involving a single elementary reaction at the origin of each observed change in composition. An…
The soliton wave model of action potentials, and the proposal of induced lipid pores, are potentially paradigm shifting ideas which challenge accepted views of the Hodgkin-Huxley model and of protein-based ion channels. These two proposals…
The phenomenon of apparent slip in micro-channel flows is analyzed by means of a two-phase mesoscopic lattice Boltzmann model including non-ideal fluid-fluid and fluid-wall interactins. The weakly-inhomogeneous limit of this model is solved…
We analyze the complex networks associated with brain electrical activity. Multichannel EEG measurements are first processed to obtain 3D voxel activations using the tomographic algorithm LORETA. Then, the correlation of the current…
The Boltzmann distribution of a protein provides a roadmap to all of its functional states. Normalizing flows are a promising tool for modeling this distribution, but current methods are intractable for typical pharmacological targets; they…
The influence of stable and unstable stratification on the amplification of coherent structures in turbulent channel flows is investigated by computing the linear response to stochastic forcing. The responses to momentum and thermal forcing…
In materials that do not allow birefringent phase-matching or periodic poling we propose to use waveguides to exploit the tensor structure of the second order nonlinearity for quasi-phase matching of nonlinear interactions. In particular,…
Irradiation of cell monolayers by monoenergetic ions has made it possible to establish survival curves at individual values of linear energy transfer. The two-step model of radiobiological mechanism proposed recently by Judas and Lokajicek…
This study focus on the correlation between entrance channel properties and incomplete fusion reaction. The dynamics of heavy-ion fusion reactions involved in the interaction of 12C and 16O with 169Tm and 75As targets were examined at…
The excitation functions for different fragments produced in the 27Al + 27Al dissipative collisions have been measured in steps of 250 keV in the energy range 122 - 132 MeV. Deep inelastic processes have been selected by integrating events…