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Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

Neurons and Cognition · Quantitative Biology 2012-03-06 Xuejuan Zhang , Jianfeng Feng

A central question in neuroscience is to understand how noisy firing patterns are used to transmit information. Because neural spiking is noisy, spiking patterns are often quantified via pairwise correlations, or the probability that two…

Neurons and Cognition · Quantitative Biology 2017-05-29 Andrea K. Barreiro , Cheng Ly

Brains learn to represent information from a large set of stimuli, typically by weak supervision. Unsupervised learning is therefore a natural approach for exploring the design of biological neural networks and their computations.…

Neurons and Cognition · Quantitative Biology 2025-10-17 Roy Urbach , Elad Schneidman

Different brain areas, such as the cortex and, more specifically, the prefrontal cortex, show great recurrence in their connections, even in early sensory areas. {Several approaches and methods based on trained networks have been proposed…

Neurons and Cognition · Quantitative Biology 2022-04-25 Cecilia Jarne

We introduce bio-inspired artificial neural networks consisting of neurons that are additionally characterized by spatial positions. To simulate properties of biological systems we add the costs penalizing long connections and the proximity…

Neural and Evolutionary Computing · Computer Science 2019-10-08 Maciej Wołczyk , Jacek Tabor , Marek Śmieja , Szymon Maszke

In this paper, we build a model for biological neural nets where the activity of the network is described by Hawkes processes having a variable length memory. The particularity of this paper is to deal with an infinite number of components.…

Probability · Mathematics 2015-09-18 Pierre Hodara , Eva Löcherbach

Motifs are patterns of subgraphs of complex networks. We studied the impact of such patterns of connectivity on the level of correlated, or synchronized, spiking activity among pairs of cells in a recurrent network model of integrate and…

Neurons and Cognition · Quantitative Biology 2015-06-05 Yu Hu , James Trousdale , Kresimir Josic , Eric Shea-Brown

Bayesian Networks may be appealing for clinical decision-making due to their inclusion of causal knowledge, but their practical adoption remains limited as a result of their inability to deal with unstructured data. While neural networks do…

Machine Learning · Computer Science 2022-11-16 Paloma Rabaey , Cedric De Boom , Thomas Demeester

In this work we study biological neural networks from an algorithmic perspective, focusing on understanding tradeoffs between computation time and network complexity. Our goal is to abstract real neural networks in a way that, while not…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-04-30 Nancy Lynch , Cameron Musco , Merav Parter

We present a general class of machine learning algorithms called parametric matrix models. In contrast with most existing machine learning models that imitate the biology of neurons, parametric matrix models use matrix equations that…

Machine Learning · Computer Science 2025-01-07 Patrick Cook , Danny Jammooa , Morten Hjorth-Jensen , Daniel D. Lee , Dean Lee

Next-item prediction is a a popular problem in the recommender systems domain. As the name suggests, the task is to recommend subsequent items that a user would be interested in given contextual information and historical interaction data.…

Information Retrieval · Computer Science 2022-05-12 Manoj Reddy Dareddy , Zijun Xue , Nicholas Lin , Junghoo Cho

Neural circuits in the brain perform a variety of essential functions, including input classification, pattern completion, and the generation of rhythms and oscillations that support processes such as breathing and locomotion. There is also…

Neurons and Cognition · Quantitative Biology 2024-10-16 Juliana Londono Alvarez

The study of neuronal morphology is important not only for its potential relationship with neuronal dynamics, but also as a means to classify diverse types of cells and compare than among species, organs, and conditions. In the present…

Neurons and Cognition · Quantitative Biology 2024-03-11 Alexandre Benatti , Henrique F. de Arruda , Luciano da F. Costa

Modeling uncertainty in deep neural networks, despite recent important advances, is still an open problem. Bayesian neural networks are a powerful solution, where the prior over network weights is a design choice, often a normal…

Machine Learning · Statistics 2019-10-29 Raanan Y. Rohekar , Yaniv Gurwicz , Shami Nisimov , Gal Novik

Computational methods for discovering patterns of local correlations in sequences are important in computational biology. Here we show how to determine the optimal partitioning of aligned sequences into non-overlapping segments such that…

Computational Engineering, Finance, and Science · Computer Science 2012-06-26 Joseph Bockhorst , Nebojsa Jojic

In "The Organization of Behavior" (Hebb, 1949), Hebb suggested that the propagation of activity between transiently grouped neurons plays an important role in behavior. Since then, multiple studies have provided evidence supporting Hebb's…

Neurons and Cognition · Quantitative Biology 2021-05-28 Ohad Felsenstein , Moshe Abeles

Hypergraphs serve as an effective tool widely adopted to characterize higher-order interactions in complex systems. The most intuitive and commonly used mathematical instrument for representing a hypergraph is the incidence matrix, in which…

Social and Information Networks · Computer Science 2026-04-22 Junhao Bian , Yilin Bi , Tao Zhou

When a neuron fires and the resulting action potential travels down its axon toward other neurons' dendrites, the effect on each of those neurons is mediated by the weight of the synapse that separates it from the firing neuron. This…

Neurons and Cognition · Quantitative Biology 2010-02-19 Andre Nathan , Valmir C. Barbosa

Traditional neural networks assume vectorial inputs as the network is arranged as layers of single line of computing units called neurons. This special structure requires the non-vectorial inputs such as matrices to be converted into…

Machine Learning · Computer Science 2016-12-12 Junbin Gao , Yi Guo , Zhiyong Wang

Attractor dynamics are a fundamental computational motif in neural circuits, supporting diverse cognitive functions through stable, self-sustaining patterns of neural activity. In these lecture notes, we review four key examples that…

Neurons and Cognition · Quantitative Biology 2026-01-30 Tala Fakhoury , Elia Turner , Sushrut Thorat , Athena Akrami
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