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Living systems, particularly multicellular systems, often seem hopelessly complex. But recent studies have suggested that beneath this complexity, there may be unifying quantitative principles that we are only now starting to unravel. All…

Molecular Networks · Quantitative Biology 2016-03-01 Eduardo P. Olimpio , Diego R. Gomez-Alvarez , Hyun Youk

Ordered polarity alignment of a cell population plays a vital role in biology, such as in hair follicle alignment and asymmetric cell division. Here, we propose a theoretical framework for the understanding of generic dynamical properties…

Pattern Formation and Solitons · Physics 2016-12-13 Kaori Sugimura , Hiroshi Kori

In this paper we analyze the stability of different coupling strategies for multidomain PDEs that arise in general circulation models used in climate simulations. We focus on fully coupled ocean-atmosphere models that are needed to…

Numerical Analysis · Mathematics 2019-09-18 Hong Zhang , Zhengyu Liu , Emil Constantinescu , Robert Jacob

Continuous-time neural processes are performant sequential decision-makers that are built by differential equations (DE). However, their expressive power when they are deployed on computers is bottlenecked by numerical DE solvers. This…

The ability of a cell to communicate with its environment is essential for key cellular functions like replication, metabolism, or cell fate decisions. The involved molecular mechanisms are highly dynamic and difficult to capture…

Human-Computer Interaction · Computer Science 2025-09-11 Lena Cibulski , Fiete Haack , Adelinde Uhrmacher , Stefan Bruckner

Decoupling is an important tool to prolong the coherence time of quantum systems. Most decoupling schemes have been assuming selective controls on the system and it is believed that with global pulses one can only decouple systems with…

Quantum Physics · Physics 2015-06-24 Haidong Yuan , Van D. M. Koroleva , Navin Khaneja

This paper deals with the numerical integration of well-posed multiscale systems of ODEs or evolutionary PDEs. As these systems appear naturally in engineering problems, time-subcycling techniques are widely used every day to improve…

Analysis of PDEs · Mathematics 2015-10-07 Guillaume Dujardin , Pauline Lafitte

The present work aims to show one of the advantages of using the property of closure under coupling in the DEVS specification. The advantage concerned in this paper attempts to address the need for memory resources during the simulation of…

Cellular Automata and Lattice Gases · Physics 2020-09-03 Youcef Dahmani , Maamar El Amine Hamri , Nesrine Driouche

This paper presents a backstepping solution for the output feedback control of general linear heterodirectional hyperbolic PDE-ODE systems with spatially-varying coefficients. Thereby, the coupling in the PDE is in-domain and at the…

Optimization and Control · Mathematics 2017-11-03 Joachim Deutscher , Nicole Gehring , Richard Kern

A complex system with cluttered observations may be a coupled mixture of multiple simple sub-systems corresponding to latent entities. Such sub-systems may hold distinct dynamics in the continuous-time domain; therein, complicated…

Machine Learning · Computer Science 2025-02-17 Zihan Zhou , Tianshu Yu

Computer simulation is an important tool for scientific progress, especially when lab experiments are either extremely costly and difficult or lack the required resolution. However, all of the simulation methods come with limitations. In…

Fluid Dynamics · Physics 2023-08-04 Edward R. Smith , Panagiotis E. Theodorakis

Ordinary differential equations (ODEs) are widely used to model biological, (bio-)chemical and technical processes. The parameters of these ODEs are often estimated from experimental data using ODE-constrained optimisation. This article…

Optimization and Control · Mathematics 2015-11-06 Anna Fiedler , Fabian J. Theis , Jan Hasenauer

Coordinated multi-point (CoMP) transmission has been widely recognized as a spectrally efficient technique in future cellular systems. To exploit the abundant patial resources provided by the cooperating base stations, however, considerable…

Networking and Internet Architecture · Computer Science 2012-09-03 Qian Zhang , Chenyang Yang

A numerical method for coupled 3D-1D problems with discontinuous solutions at the interfaces is derived and discussed. This extends a previous work on the subject where only continuous solutions were considered. Thanks to properly defined…

Numerical Analysis · Mathematics 2022-03-04 Stefano Berrone , Denise Grappein , Stefano Scialò

Ordinary differential equations (ODEs) can model the transition of cell states over time. Bifurcation theory is a branch of dynamical systems which studies changes in the behavior of an ODE system while one or more parameters are varied. We…

Cell Behavior · Quantitative Biology 2023-07-06 Brenda Delamonica , Gabor Balazsi , Michael Shub

Decoupling uplink (UL) and downlink (DL) is a new architectural paradigm where DL and UL are not constrained to be associated to the same base station (BS). Building upon this paradigm, the goal of the present paper is to provide lower,…

Information Theory · Computer Science 2016-10-11 Alexis I. Aravanis , Olga Munoz , Antonio Pascual-Iserte , Josep Vidal

By spreading phases on the unit circle, desynchronization algorithm is a powerful tool to achieve round-robin scheduling, which is crucial in applications as diverse as media access control of communication networks, realization of…

Systems and Control · Computer Science 2016-03-11 Huan Gao , Yongqiang Wang

We consider the downlink of a cellular network with multiple cells and multi-antenna base stations, including a realistic distance-dependent pathloss model, clusters of cooperating cells, and general "fairness" requirements. Beyond Monte…

Information Theory · Computer Science 2016-11-17 Hoon Huh , Giuseppe Caire , Sung-Hyun Moon , Young-Tae Kim , Inkyu Lee

We consider the problem of minimization of sum transmission energy in cellular networks where coupling occurs between cells due to mutual interference. The coupling relation is characterized by the signal-to-interference-and-noise-ratio…

Information Theory · Computer Science 2016-11-18 Chin Keong Ho , Di Yuan , Lei Lei , Sumei Sun

Biological systems are non-linear, include unobserved variables and the physical principles that govern their dynamics are partly unknown. This makes the characterization of their behavior very challenging. Notably, their activity occurs on…

Quantitative Methods · Quantitative Biology 2025-06-27 Andréa Ducos , Audrey Denizot , Thomas Guyet , Hugues Berry