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GP (for Graph Programs) is a rule-based, nondeterministic programming language for solving graph problems at a high level of abstraction, freeing programmers from handling low-level data structures. The core of GP consists of four…

Logic in Computer Science · Computer Science 2010-04-08 Detlef Plump , Sandra Steinert

A numerically effective procedure for determining weakly reversible chemical reaction networks that are linearly conjugate to a known reaction network is proposed in this paper. The method is based on translating the structural and…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

Large language models have evolved to process multiple modalities beyond text, such as images and audio, which motivates us to explore how to effectively leverage them for graph reasoning tasks. The key question, therefore, is how to…

The problem of molecular generation has received significant attention recently. Existing methods are typically based on deep neural networks and require training on large datasets with tens of thousands of samples. In practice, however,…

Machine Learning · Computer Science 2022-03-16 Minghao Guo , Veronika Thost , Beichen Li , Payel Das , Jie Chen , Wojciech Matusik

A graphical language addresses the need to communicate medical information in a synthetic way. Medical concepts are expressed by icons conveying fast visual information about patients' current state or about the known effects of drugs. In…

Computation and Language · Computer Science 2014-11-18 Pascal Vaillant , Jean-Baptiste Lamy

A ChatGPT-like system for drug compounds could be a game-changer in pharmaceutical research, accelerating drug discovery, enhancing our understanding of structure-activity relationships, guiding lead optimization, aiding drug repurposing,…

Biomolecules · Quantitative Biology 2023-09-11 Youwei Liang , Ruiyi Zhang , Li Zhang , Pengtao Xie

Many real networks can be understood as two complementary networks with two kind of nodes. This is the case of metabolic networks where the first network has chemical compounds as nodes and the second one has nodes as reactions. The second…

Molecular Networks · Quantitative Biology 2007-05-23 J. C. Nacher , N. Ueda , T. Yamada , M. Kanehisa , T. Akutsu

This paper describes a novel Python package, named causalgraph, for modeling and saving causal graphs embedded in knowledge graphs. The package has been designed to provide an interface between causal disciplines such as causal discovery…

Artificial Intelligence · Computer Science 2023-01-23 Sven Pieper , Carl Willy Mehling , Dominik Hirsch , Tobias Lüke , Steffen Ihlenfeldt

Node graph systems are used ubiquitously for material design in computer graphics. They allow the use of visual programming to achieve desired effects without writing code. As high-level design tools they provide convenience and…

Graphics · Computer Science 2023-04-27 Yiwei Hu , Paul Guerrero , Miloš Hašan , Holly Rushmeier , Valentin Deschaintre

The problem of accelerating drug discovery relies heavily on automatic tools to optimize precursor molecules to afford them with better biochemical properties. Our work in this paper substantially extends prior state-of-the-art on…

Chemical Physics · Physics 2019-10-22 Wengong Jin , Regina Barzilay , Tommi Jaakkola

The purpose of this review is to introduce the reader to graph kernels and the corresponding literature, with an emphasis on those with direct application to chemoinformatics. Graph kernels are functions that allow for the inference of…

Machine Learning · Statistics 2022-08-29 James Young

The dramatic increase of complex, multi-step, and rapidly evolving attacks in dynamic networks involves advanced cyber-threat detectors. The GPML (Graph Processing for Machine Learning) library addresses this need by transforming raw…

Machine Learning · Computer Science 2025-05-15 Majed Jaber , Julien Michel , Nicolas Boutry , Pierre Parrend

We describe a strategy language to control the application of graph rewriting rules, and show how this language can be used to write high-level declarative programs in several application areas. This language is part of a graph-based…

Programming Languages · Computer Science 2010-12-30 Maribel Fernández , Olivier Namet

Molecular property calculations are the bedrock of chemical physics. High-fidelity \textit{ab initio} modeling techniques for computing the molecular properties can be prohibitively expensive, and motivate the development of…

Machine Learning · Computer Science 2022-11-28 Hatem Helal , Jesun Firoz , Jenna Bilbrey , Mario Michael Krell , Tom Murray , Ang Li , Sotiris Xantheas , Sutanay Choudhury

In recent years, research on transforming natural language into graph query language (NL2GQL) has been increasing. Most existing methods focus on single-turn transformation from NL to GQL. In practical applications, user interactions with…

Artificial Intelligence · Computer Science 2025-08-05 Yuanyuan Liang , Lei Pan , Tingyu Xie , Yunshi Lan , Weining Qian

With the increase of the search for computational models where the expression of parallelism occurs naturally, some paradigms arise as options for the next generation of computers. In this context, dynamic Dataflow and Gamma - General…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-05 Rui R. Mello Junior , Leandro S. Araujo , Tiago A. O. Alves , Leandro A. J. Marzulo , Gabriel A. L. Paillard , Felipe M. G. França

String diagrams are a powerful tool for reasoning about physical processes, logic circuits, tensor networks, and many other compositional structures. Dixon, Duncan and Kissinger introduced string graphs, which are a combinatoric…

Category Theory · Mathematics 2014-04-02 Aleks Kissinger , Alex Merry , Matvey Soloviev

Graph representations of programs are commonly a central element of machine learning for code research. We introduce an open source Python library python_graphs that applies static analysis to construct graph representations of Python…

Machine Learning · Computer Science 2022-08-17 David Bieber , Kensen Shi , Petros Maniatis , Charles Sutton , Vincent Hellendoorn , Daniel Johnson , Daniel Tarlow

As a fundamental task in computational chemistry, retrosynthesis prediction aims to identify a set of reactants to synthesize a target molecule. Existing template-free approaches only consider the graph structures of the target molecule,…

Computation and Language · Computer Science 2024-01-29 Yifeng Liu , Hanwen Xu , Tangqi Fang , Haocheng Xi , Zixuan Liu , Sheng Zhang , Hoifung Poon , Sheng Wang

To design a drug given a biological molecule by using deep learning methods, there are many successful models published recently. People commonly used generative models to design new molecules given certain protein. LiGAN was regarded as…

Machine Learning · Computer Science 2022-11-15 Haotian Zhang , Linxiaoyi Wan