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Geometric uncertainty can degrade treatment quality in radiation therapy. While margins and robust optimization mitigate these effects, they provide only implicit control over clinical goal fulfillment probability. We therefore develop a…

Medical Physics · Physics 2026-01-14 Albin Fredriksson , Erik Engwall , Jenneke de Jong , Johan Sundström

The challenge of removing cancerous cells lies in the limitation of organ at risk, which restricts the ability to increase the radiation dose adequately for enhancing treatment effectiveness. This survey provides a comprehensive overview of…

Medical Physics · Physics 2023-07-27 Amir Moslemi , Navid Khaledi

This study investigates the sensitivity and specificity of the MapCHECK phantom housed in MapPHAN to errors in conformal arc Stereotactic Ablative Body Radiotherapy (SABR). A specific focus is applied to Organ At Risk (OAR) dosimetry.…

Medical Physics · Physics 2025-08-22 Nathan I. N. Henry , Christopher M. Thompson , Steven Marsh , Jack D. Aylward

Superconducting, curved magnets can reduce accelerator footprints by producing strong fields (>3T) and reducing the total number of magnets through their capability for combined-function multipolar fields, making them an attractive choice…

Accelerator Physics · Physics 2025-02-10 Hannah X. Q. Norman , Robert B. Appleby , Elena Benedetto , Suzie L. Sheehy

Purpose: Proton vertebral body sparing craniospinal irradiation (VBS CSI) treats the thecal sac while avoiding the anterior vertebral bodies in effort to reduce myelosuppression and growth inhibition. However, robust treatment planning…

The majority of current research in deep learning based image registration addresses inter-patient brain registration with moderate deformation magnitudes. The recent Learn2Reg medical registration benchmark has demonstrated that…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Mattias P. Heinrich , Lasse Hansen

Automating the radiotherapy treatment planning process is a technically challenging problem. The majority of automated approaches have focused on customizing and inferring dose volume objectives to used in plan optimization. In this work we…

Medical Physics · Physics 2017-01-04 Chris McIntosh , Thomas G. Purdie

CBCT images suffer from acute shading artifacts primarily due to scatter. Numerous image-domain correction algorithms have been proposed in the literature that use patient-specific planning CT images to estimate shading contributions in…

Computer Vision and Pattern Recognition · Computer Science 2018-01-18 Awais Ashfaq , Jonas Adler

Positivity violations can complicate estimation and interpretation of causal dose-response curves (CDRCs) for continuous interventions. Weighting-based methods are designed to handle limited overlap, but the resulting weighted targets can…

Methodology · Statistics 2026-02-13 Han Bao , Michael Schomaker

Purpose: LATTICE, a form of spatially fractionated radiation therapy that delivers high-dose peaks and low-dose valleys within the target, has been clinically utilized for treating bulky tumors. However, its application to…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Weijie Zhang , Yuting Lin , Hao Gao

We give a scenario-based treatment plan optimization formulation that is equivalent to planning with geometric margins if the scenario doses are calculated using the static dose cloud approximation. If the scenario doses are instead…

Medical Physics · Physics 2016-03-23 Albin Fredriksson , Rasmus Bokrantz

Clinical fusion of Single Photon Emission Computed Tomography Myocardial Perfusion Imaging (SPECT MPI) and Computed Tomography Angiography (CTA) remains limited by cross-modality misregistration and reliance on manual landmarks, which can…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Ni Yao , Xiangyu Liu , Shaojie Tang , Danyang Sun , Chuang Han , Yanting Li , Jiaofen Nan , Chengyang Li , Fubao Zhu , Chen Zhao , Zhihui Xu , Weihua Zhou

The FLASH effect, characterized by potential sparing of organs at risk (OAR) through ultra-high dose rate irradiation, has garnered significant attention for its capability to address indications previously untreatable at conventional dose…

Medical Physics · Physics 2024-10-16 S. Wuyckens , M. Chocan Vera , R. Nilsson , V. Wase , D. Di Perri , X. Geets , E. Sterpin , J. A. Lee

We present an initial examination of a novel approach to accurately position a patient during head and neck intensity modulated radiotherapy (IMRT). Position-based visual-servoing of a radio-transparent soft robot is used to control the…

Robotics · Computer Science 2017-02-08 Olalekan Ogunmolu , Xuejun Gu , Steve Jiang , Nicholas Gans

Transcranial magnetic stimulation (TMS) is a technique for noninvasively stimulating a brain area for therapeutic, rehabilitation treatments and neuroscience research. Despite our understanding of the physical principles and experimental…

Neurons and Cognition · Quantitative Biology 2020-12-30 Jose Gomez-Tames , Ilkka Laakso , Akimasa Hirata

Delineating and planning with respect to regions suspected to contain microscopic tumor cells is an inherently uncertain task in radiotherapy. The recently proposed \textit{clinical target distribution} (CTD) is an alternative to the…

Medical Physics · Physics 2023-04-26 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson

View planning for the acquisition of cardiac magnetic resonance imaging (CMR) requires acquaintance with the cardiac anatomy and remains a challenging task in clinical practice. Existing approaches to its automation relied either on an…

Image and Video Processing · Electrical Eng. & Systems 2021-09-27 Dong Wei , Kai Ma , Yefeng Zheng

Advanced radiotherapy approaches such as FLASH irradiation and spatially fractionated radiotherapy (SFRT) show potential to improve the therapeutic ratio, yet their biological mechanisms and optimal delivery parameters remain uncertain.…

This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adapt the model to three different internal treatment planning…

Deep learning-based medical image segmentation is increasingly used to support clinical diagnosis and develop new treatment strategies. However, model performance remains limited by the scarcity of high-quality annotated data and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Nathan Molinier , Hendrik Möller , Thomas Dagonneau , Anna Curto-Vilalta , Robert Graf , Matan Atad , Daniel Rueckert , Jan S. Kirschke , Julien Cohen-Adad
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