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Massive data collection holds the promise of a better understanding of complex phenomena and, ultimately, better decisions. Representation learning has become a key driver of deep learning applications, as it allows learning latent spaces…

Machine Learning · Computer Science 2025-11-10 Caroline Uhler , Jiaqi Zhang

Knowledge representation has gained in relevance as data from the ubiquitous digitization of behaviors amass and academia and industry seek methods to understand and reason about the information they encode. Success in this pursuit has…

Computers and Society · Computer Science 2018-11-21 Zachary A. Pardos , Andrew Joo Hun Nam

Most pretrained language models rely on subword tokenization, which processes text as a sequence of subword tokens. However, different granularities of text, such as characters, subwords, and words, can contain different kinds of…

Computation and Language · Computer Science 2024-04-09 Yilin Wang , Xinyi Hu , Matthew R. Gormley

Imitation learning has emerged as a powerful paradigm in robot manipulation, yet its generalization capability remains constrained by object-specific dependencies in limited expert demonstrations. To address this challenge, we propose…

Robotics · Computer Science 2025-06-27 Zhuochen Miao , Jun Lv , Hongjie Fang , Yang Jin , Cewu Lu

Encoding facts as representations of entities and binary relationships between them, as learned by knowledge graph representation models, is useful for various tasks, including predicting new facts, question answering, fact checking and…

Machine Learning · Computer Science 2022-02-01 Ivana Balažević

Meta-learning approaches have shown great success in vision and language domains. However, few studies discuss the practice of meta-learning for large-scale industrial applications. Although e-commerce companies have spent many efforts on…

Machine Learning · Computer Science 2020-10-12 Hao Gong , Qifang Zhao , Tianyu Li , Derek Cho , DuyKhuong Nguyen

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…

Quantitative Methods · Quantitative Biology 2020-04-13 Thomas Gaudelet , Noel Malod-Dognin , Jon Sanchez-Valle , Vera Pancaldi , Alfonso Valencia , Natasa Przulj

Clinical Practice Guidelines (CPGs) for cancer diseases evolve rapidly due to new evidence generated by active research. Currently, CPGs are primarily published in a document format that is ill-suited for managing this developing knowledge.…

Artificial Intelligence · Computer Science 2023-07-21 Pralaypati Ta , Bhumika Gupta , Arihant Jain , Sneha Sree C , Arunima Sarkar , Keerthi Ram , Mohanasankar Sivaprakasam

Modern self-supervised predictive architectures excel at capturing complex statistical correlations from high-dimensional data but lack mechanisms to internalize verifiable human logic, leaving them susceptible to spurious correlations and…

Machine Learning · Computer Science 2026-03-17 Yongchao Huang , Hassan Raza

Today we have a good theoretical understanding of the representational power of Graph Neural Networks (GNNs). For example, their limitations have been characterized in relation to a hierarchy of Weisfeiler-Lehman (WL) isomorphism tests.…

Machine Learning · Computer Science 2023-03-08 Mohammad Sadegh Akhondzadeh , Vijay Lingam , Aleksandar Bojchevski

Biological foundation models have shown strong performance in single-cell representation learning by applying transformer architectures directly to gene-expression matrices. However, these approaches predominantly operate in static settings…

Machine Learning · Computer Science 2026-05-28 Manuel Dileo , Andrea Sottoriva

Knowledge graphs represent real-world entities and their relations in a semantically-rich structure supported by ontologies. Exploring this data with machine learning methods often relies on knowledge graph embeddings, which produce latent…

Machine Learning · Computer Science 2023-06-23 Rita T. Sousa , Sara Silva , Catia Pesquita

Representation learning has driven major advances in natural image analysis by enabling models to acquire high-level semantic features. In microscopy imaging, however, it remains unclear what current representation learning methods actually…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ivan Svatko , Maxime Sanchez , Ihab Bendidi , Gilles Cottrell , Auguste Genovesio

Despite their widespread utility across domains, basic network models face fundamental limitations when applied to complex biological systems, particularly in neuroscience. This paper critically examines these limitations and explores…

Other Quantitative Biology · Quantitative Biology 2024-11-07 Luiz Pessoa

This paper presents a novel approach that leverages domain variability to learn representations that are conditionally invariant to unwanted variability or distractors. Our approach identifies both spurious and invariant latent features…

Machine Learning · Computer Science 2023-07-04 Hananeh Aliee , Ferdinand Kapl , Soroor Hediyeh-Zadeh , Fabian J. Theis

Large contingency tables summarizing categorical variables arise in many areas. For example in biology when a large number of biomarkers are cross-tabulated according to their discrete expression level. Interactions of the variables are…

Methodology · Statistics 2009-11-17 Corinne Dahinden , Markus Kalisch , Peter Bühlmann

Machine learning methods adapt the parameters of a model, constrained to lie in a given model class, by using a fixed learning procedure based on data or active observations. Adaptation is done on a per-task basis, and retraining is needed…

Machine Learning · Computer Science 2021-10-22 Osvaldo Simeone , Sangwoo Park , Joonhyuk Kang

Clinical text classification is an important problem in medical natural language processing. Existing studies have conventionally focused on rules or knowledge sources-based feature engineering, but only a few have exploited effective…

Computation and Language · Computer Science 2018-07-23 Liang Yao , Chengsheng Mao , Yuan Luo

Graph neural networks (GNNs) demonstrate great performance in compound property and activity prediction due to their capability to efficiently learn complex molecular graph structures. However, two main limitations persist including…

Biomolecules · Quantitative Biology 2023-10-10 Apakorn Kengkanna , Masahito Ohue

Learning the underlying patterns in data goes beyond instance-based generalization to external knowledge represented in structured graphs or networks. Deep learning that primarily constitutes neural computing stream in AI has shown…

Artificial Intelligence · Computer Science 2023-09-04 Ugur Kursuncu , Manas Gaur , Amit Sheth
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