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Collecting multiple types of data on the same set of subjects is common in modern scientific applications including, genomics, metabolomics, and neuroimaging. Joint and Individual Variance Explained (JIVE) seeks a low-rank approximation of…

Machine Learning · Statistics 2026-03-16 Raphiel J. Murden , Ganzhong Tian , Deqiang Qiu , Benajmin B. Risk

Estimating the number of distinct values (NDV) in a column is useful for many tasks in database systems, such as columnstore compression and data profiling. In this work, we focus on how to derive accurate NDV estimations from random…

Machine Learning · Computer Science 2022-02-08 Renzhi Wu , Bolin Ding , Xu Chu , Zhewei Wei , Xiening Dai , Tao Guan , Jingren Zhou

Modern neural network architectures have achieved remarkable accuracies but remain highly dependent on their training data, often lacking interpretability in their learned mappings. While effective on large datasets, they tend to overfit on…

Machine Learning · Computer Science 2025-03-19 Pavia Bera , Sanjukta Bhanja

As the large amount of sequencing data accumulated in past decades and it is still accumulating, we need to handle the more and more sequencing data. As the fast development of the computing technologies, we now can handle a large amount of…

Other Quantitative Biology · Quantitative Biology 2021-01-05 Songting Shi

Variance reduction is a family of powerful mechanisms for stochastic optimization that appears to be helpful in many machine learning tasks. It is based on estimating the exact gradient with some recursive sequences. Previously, many papers…

Optimization and Control · Mathematics 2025-11-07 Aleksandr Shestakov , Valery Parfenov , Aleksandr Beznosikov

Autoregressive (AR) decoding is a major latency bottleneck for large language models. Speculative decoding (SD) accelerates AR by letting a drafter propose multi-token blocks that a verifier accepts or rejects. However, many SD systems…

Machine Learning · Computer Science 2025-10-08 Shrenik Bhansali , Larry Heck

Gradient matching is a promising tool for learning parameters and state dynamics of ordinary differential equations. It is a grid free inference approach, which, for fully observable systems is at times competitive with numerical…

Machine Learning · Statistics 2018-04-11 Nico S. Gorbach , Stefan Bauer , Joachim M. Buhmann

Deep Gaussian processes (DGPs) enable expressive hierarchical Bayesian modeling but pose substantial challenges for posterior inference, especially over inducing variables. Denoising diffusion variational inference (DDVI) addresses this by…

Machine Learning · Computer Science 2026-02-13 Jian Xu , Qibin Zhao , John Paisley , Delu Zeng

The article develops a hybrid Variational Bayes algorithm that combines the mean-field and fixed-form Variational Bayes methods. The new estimation algorithm can be used to approximate any posterior without relying on conjugate priors. We…

Methodology · Statistics 2013-08-09 David J Nott , Minh-Ngoc Tran , Anthony Y. C. Kuk , Robert Kohn

With the wide adoption of machine learning techniques, requirements have evolved beyond sheer high performance, often requiring models to be trustworthy. A common approach to increase the trustworthiness of such systems is to allow them to…

Machine Learning · Computer Science 2023-11-16 Andrea Pugnana , Carlos Mougan , Dan Saattrup Nielsen

Linear mixed models are a versatile statistical tool to study data by accounting for fixed effects and random effects from multiple sources of variability. In many situations, a large number of candidate fixed effects is available and it is…

Methodology · Statistics 2022-09-09 Emanuele Degani , Luca Maestrini , Dorota Toczydłowska , Matt P. Wand

Many problems in Physics and Chemistry are formulated as the minimization of a functional. Therefore, methods for solving these problems typically require differentiating maps whose input and/or output are functions -- commonly referred to…

Mathematical Software · Computer Science 2024-06-25 Kangbo Li , Anil Damle

Current state-of-the-art optimizers are adaptive gradient-based optimization methods such as Adam. Recently, there has been an increasing interest in formulating gradient-based optimizers in a probabilistic framework for better modeling the…

Machine Learning · Computer Science 2025-04-21 Haotian Chen , Anna Kuzina , Babak Esmaeili , Jakub M Tomczak

Models of complex systems are often formalized as sequential software simulators: computationally intensive programs that iteratively build up probable system configurations given parameters and initial conditions. These simulators enable…

Machine Learning · Statistics 2015-06-02 Ardavan Saeedi , Vlad Firoiu , Vikash Mansinghka

Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

Biomolecules · Quantitative Biology 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

In this article, we propose a variational inference formulation of auto-associative memories, allowing us to combine perceptual inference and memory retrieval into the same mathematical framework. In this formulation, the prior probability…

Machine Learning · Computer Science 2022-10-18 Louis Annabi , Alexandre Pitti , Mathias Quoy

Estimating the structure of Bayesian networks as directed acyclic graphs (DAGs) from observational data is a fundamental challenge, particularly in causal discovery. Bayesian approaches excel by quantifying uncertainty and addressing…

Machine Learning · Computer Science 2026-02-17 Edwin V. Bonilla , Pantelis Elinas , He Zhao , Maurizio Filippone , Vassili Kitsios , Terry O'Kane

Bayesian inference has become an important tool to solve inverse problems and to quantify uncertainties in their solutions. Variational inference is a method that provides probabilistic, Bayesian solutions efficiently by using optimization.…

Geophysics · Physics 2025-10-15 Xin Zhang , Andrew Curtis

Symbolic regression discovers explicit, interpretable equations without assuming a functional form in advance. A Bayesian approach strengthens this through probability distributions over candidate expressions, thus quantifying uncertainty…

Machine Learning · Computer Science 2026-05-05 James Butterworth , Gevik Grigorian , Alejandro DiazDelaO

We present an exact Bayesian inference method for discrete statistical models, which can find exact solutions to a large class of discrete inference problems, even with infinite support and continuous priors. To express such models, we…

Programming Languages · Computer Science 2023-11-08 Fabian Zaiser , Andrzej S. Murawski , Luke Ong