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We present a statistical perspective on boosting. Special emphasis is given to estimating potentially complex parametric or nonparametric models, including generalized linear and additive models as well as regression models for survival…

Methodology · Statistics 2008-12-18 Peter Bühlmann , Torsten Hothorn

Optunity is a free software package dedicated to hyperparameter optimization. It contains various types of solvers, ranging from undirected methods to direct search, particle swarm and evolutionary optimization. The design focuses on ease…

Machine Learning · Computer Science 2014-12-04 Marc Claesen , Jaak Simm , Dusan Popovic , Yves Moreau , Bart De Moor

The human nervous system utilizes synaptic plasticity to solve optimization problems. Previous studies have tried to add the plasticity factor to the training process of artificial neural networks, but most of those models require complex…

Neural and Evolutionary Computing · Computer Science 2022-04-13 Amir Valizadeh

Evolutionary algorithms (EAs) provide unique advantages for optimizing neural networks in complex search spaces. This paper introduces a new web platform, NeuroEvo (neuroevo.io), that allows users to interactively design and train neural…

Neural and Evolutionary Computing · Computer Science 2022-10-04 Philip Schroeder

Hyperparameter optimization and neural architecture search can become prohibitively expensive for regular black-box Bayesian optimization because the training and evaluation of a single model can easily take several hours. To overcome this,…

Optimization modeling via mixed-integer linear programming (MILP) is fundamental to industrial planning and scheduling, yet translating natural-language requirements into solver-executable models and maintaining them under evolving business…

Artificial Intelligence · Computer Science 2026-03-24 Yiliu He , Tianle Li , Binghao Ji , Zhiyuan Liu , Di Huang

Background: Clinical prediction models are increasingly used to inform healthcare decisions, but determining the minimum sample size for their development remains a critical and unresolved challenge. Inadequate sample sizes can lead to…

Machine Learning · Computer Science 2026-03-02 Diana Shamsutdinova , Felix Zimmer , Oyebayo Ridwan Olaniran , Sarah Markham , Daniel Stahl , Gordon Forbes , Ewan Carr

Applying DevOps practices to machine learning system is termed as MLOps and machine learning systems evolve on new data unlike traditional systems on requirements. The objective of MLOps is to establish a connection between different…

Software Engineering · Computer Science 2024-02-21 Pir Sami Ullah Shah , Naveed Ahmad , Mirza Omer Beg

Poor generalization performance caused by distribution shifts in unseen domains often hinders the trustworthy deployment of deep neural networks. Many domain generalization techniques address this problem by adding a domain invariant…

The optimization of composition and processing to obtain materials that exhibit desirable characteristics has historically relied on a combination of scientist intuition, trial and error, and luck. We propose a methodology that can…

Machine Learning · Statistics 2017-07-20 Julia Ling , Max Hutchinson , Erin Antono , Sean Paradiso , Bryce Meredig

Despite the rapid development of large language models (LLMs), a fundamental challenge persists: the lack of high-quality optimization modeling datasets hampers LLMs' robust modeling of practical optimization problems from natural language…

Artificial Intelligence · Computer Science 2025-02-24 Hongliang Lu , Zhonglin Xie , Yaoyu Wu , Can Ren , Yuxuan Chen , Zaiwen Wen

Many real-world problems require to optimise trajectories under constraints. Classical approaches are based on optimal control methods but require an exact knowledge of the underlying dynamics, which could be challenging or even out of…

Applications · Statistics 2021-02-08 Florent Dewez , Benjamin Guedj , Arthur Talpaert , Vincent Vandewalle

Numerical validation is at the core of machine learning research as it allows to assess the actual impact of new methods, and to confirm the agreement between theory and practice. Yet, the rapid development of the field poses several…

A body of work has been done to automate machine learning algorithm to highlight the importance of model choice. Automating the process of choosing the best forecasting model and its corresponding parameters can result to improve a wide…

Machine Learning · Computer Science 2021-09-02 Nadhir Hassen , Irina Rish

In all but the most trivial optimization problems, the structure of the solutions exhibit complex interdependencies between the input parameters. Decades of research with stochastic search techniques has shown the benefit of explicitly…

Neural and Evolutionary Computing · Computer Science 2017-03-23 Shumeet Baluja

Nervous systems, like any organismal structure, have been shaped by evolutionary processes to increase fitness. The resulting neural 'bauplan' has to account for multiple objectives simultaneously, including computational function as well…

Neurons and Cognition · Quantitative Biology 2021-05-05 Fabian Pallasdies , Philipp Norton , Jan-Hendrik Schleimer , Susanne Schreiber

Materials design can be cast as an optimization problem with the goal of achieving desired properties, by varying material composition, microstructure morphology, and processing conditions. Existence of both qualitative and quantitative…

Computational Physics · Physics 2019-07-08 Akshay Iyer , Yichi Zhang , Aditya Prasad , Siyu Tao , Yixing Wang , Linda Schadler , L Catherine Brinson , Wei Chen

Bayesian optimization is a sequential decision making framework for optimizing expensive-to-evaluate black-box functions. Computing a full lookahead policy amounts to solving a highly intractable stochastic dynamic program. Myopic…

Machine Learning · Computer Science 2020-06-30 Shali Jiang , Daniel R. Jiang , Maximilian Balandat , Brian Karrer , Jacob R. Gardner , Roman Garnett

Target-specific peptides, such as conotoxins, exhibit exceptional binding affinity and selectivity toward ion channels and receptors. However, their therapeutic potential remains underutilized due to the limited diversity of natural…

Biomolecules · Quantitative Biology 2025-05-07 Cheng Ge , Han-Shen Tae , Zhenqiang Zhang , Lu Lu , Zhijie Huang , Yilin Wang , Tao Jiang , Wenqing Cai , Shan Chang , David J. Adams , Rilei Yu

Adaptive Computing is an application-agnostic outer loop framework to strategically deploy simulations and experiments to guide decision making for scale-up analysis. Resources are allocated over successive batches, which makes the…

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