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Generalized estimating equation (GEE) is widely adopted for regression modeling for longitudinal data, taking account of potential correlations within the same subjects. Although the standard GEE assumes common regression coefficients among…
The method of generalized estimating equations (GEE) is popular in the biostatistics literature for analyzing longitudinal binary and count data. It assumes a generalized linear model (GLM) for the outcome variable, and a working…
In this article, we study a partially linear single-index model for longitudinal data under a general framework which includes both the sparse and dense longitudinal data cases. A semiparametric estimation method based on a combination of…
Generalized estimating equations (GEE) are widely used to analyze longitudinal data; however, they are not appropriate for heteroscedastic data, because they only estimate regressor effects on the mean response{\textemdash}and therefore do…
Generalized Estimation Equations (GEE) are a well-known method for the analysis of non-Gaussian longitudinal data. This method has computational simplicity and marginal parameter interpretation. However, in the presence of missing data, it…
The Generalized Estimating Equations (GEE) approach is a widely used statistical method for analyzing longitudinal data and clustered data in clinic studies. In dentistry, due to multiple outcomes obtained from one patient, the outcomes…
In this paper, we study estimation of nonlinear models with cross sectional data using two-step generalized estimating equations (GEE) in the quasi-maximum likelihood estimation (QMLE) framework. In the interest of improving efficiency, we…
Generalized estimating equations (GEE) are of great importance in analyzing clustered data without full specification of multivariate distributions. A recent approach jointly models the mean, variance, and correlation coefficients of…
Modeling correlated or highly stratified multiple-response data becomes a common data analysis task due to modern data monitoring facilities and methods. Generalized estimating equations (GEE) is one of the popular statistical methods for…
This paper presents a simulation study comparing the performance of generalized joint regression models (GJRM) with generalized linear mixed models (GLMM) and generalized estimating equations (GEE) for regression of longitudinal data with…
In an increasing number of neuroimaging studies, brain images, which are in the form of multidimensional arrays (tensors), have been collected on multiple subjects at multiple time points. Of scientific interest is to analyze such massive…
Powerful array-based single-nucleotide polymorphism--typing platforms have recently heralded a new era in which genome-wide studies are conducted with increasing frequency. A genetic polymorphism associated with population pharmacokinetics…
Regression models applied to network data where node attributes are the dependent variables poses a methodological challenge. As has been well studied, naive regression neither properly accounts for community structure, nor does it account…
The generalized exponential distribution is a well-known probability model in lifetime data analysis and several other research areas, including precipitation modeling. Despite having broad applications for independently and identically…
In clinical trials involving paired organs such as eyes, ears, and kidneys, binary outcomes may be collected bilaterally or unilaterally. In such combined datasets, bilateral outcomes exhibit intra-subject correlation, while unilateral…
In this paper, we consider the partially linear single-index models with longitudinal data. To deal with the variable selection problem in this context, we propose a penalized procedure combined with two bias correction methods, resulting…
Generalized Estimation Equations (GEE) are a well-known method for the analysis of categorical longitudinal responses. GEE method has computational simplicity and population parameter interpretation. In the presence of missing data it is…
Design and analysis of cluster randomized trials must take into account correlation among outcomes from the same clusters. When applying standard generalized estimating equations (GEE), the first-order (e.g. treatment) effects can be…
Generalized estimating equations (GEE) is one of the most commonly used methods for marginal regression analysis of longitudinal data, especially with discrete outcomes. The GEE method models the association among the responses of a subject…
In this article, we propose a new method for analyzing longitudinal data which contain responses that are missing at random. This method consists in solving the generalized estimating equation (GEE) of Liang and Zeger (1986) in which the…